A persistent mass: A case of aggressive Angiomyxoma of the vulva
We present a case of aggressive angiomyxoma of the vulva. The patient presented with a persistent, enlarging vulvar mass, initially misdiagnosed as a Bartholin gland cyst. The patient underwent wide local excision, which resulted in total resection of the mass. Final pathology was consistent with aggressive angiomyxoma, a rare soft tissue tumor with a predilection for the female pelvis. Though rare, it is important to consider in the differential diagnosis of a pelvic mass, given the locally aggressive nature of this tumor and propensity for recurrence. (Source: Gynecologic Oncology Reports)
Source: Gynecologic Oncology Reports - July 5, 2018 Category: OBGYN Source Type: research
Spontaneous de novo vaginal adenosis resembling Bartholin’s cyst: A case report
ConclusionExcision and histology is required in suspicious cases of paravaginal cyst to rule out vaginal adenosis, a potential precursor of vaginal adenocarcinoma. Counseling and follow up will help detect early occurrence of adenocarcinoma. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - July 5, 2018 Category: General Medicine Source Type: research
Immune therapies in pancreatic ductal adenocarcinoma: Where are we now?
Abstract
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, mostly due to its resistance to treatment. Of these, checkpoint inhibitors (CPI) are inefficient when used as monotherapy, except in the case of a rare subset of tumors harboring microsatellite instability (< 2%). This inefficacy mainly resides in the low immunogenicity and non-inflamed phenotype of PDAC. The abundant stroma generates a hypoxic microenvironment and drives the recruitment of immunosuppressive cells through cancer-associated-fibroblast activation and transforming growth factor β secretion. Several strategie...
Source: World Journal of Gastroenterology : WJG - May 28, 2018 Category: Gastroenterology Authors: Hilmi M, Bartholin L, Neuzillet C Tags: World J Gastroenterol Source Type: research
Cauda equina syndrome following an uneventful spinal anesthesia in a patient undergoing drainage of the Bartholin abscess: A case report
We present a case of cauda equina syndrome following spinal anesthesia in a patient who underwent Bartholin abscess drainage.
Patient concerns:
A 23-year old female scheduled to undergo surgical drainage of Bartholin abscess. Spinal anesthesia was performed with bupivacaine and fentanyl. There were no perioperative adverse events reported. On postoperative day 1, the patient went to the emergency department describing bilateral weakness and pain of the lower extremities (LE).
Diagnoses:
Lumbar magnetic resonance imaging showed increased gadolinium accumulation in the neural sheath at the level of the cauda equina tra...
Source: Medicine - May 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Potential delay in the diagnosis of vulvar cancer and associated risk factors in women treated in German gynecological practices.
Authors: Muigai J, Jacob L, Dinas K, Kostev K, Kalder M
Abstract
The goal of this study was to estimate a potential delay in the diagnosis of vulvar cancer and identify associated risk factors in women treated in gynecological practices in Germany. The current study sample included 1,652 women from 218 gynecological practices who received an initial diagnosis of vulvar cancer (ICD 10: C51) between January 2000 and December 2015 (index date). After applying several exclusion criteria, 505 non-cancer controls were matched (1:1) to 505 vulvar cancer cases based on age, health insurance status, and index date....
Source: Oncotarget - March 3, 2018 Category: Cancer & Oncology Tags: Oncotarget Source Type: research
A persistent mass: A case of aggressive angiomyxoma of the vulva
We present a case of aggressive angiomyxoma of the vulva. The patient presented with a persistent, enlarging vulvar mass, initially misdiagnosed as a Bartholin gland cyst. The patient underwent wide local excision, which resulted in total resection of the mass. Final pathology was consistent with aggressive angiomyxoma, a rare soft tissue tumor with a predilection for the female pelvis. Though rare, it is important to consider in the differential diagnosis of a pelvic mass, given the locally aggressive nature of this tumor and propensity for recurrence. (Source: Gynecologic Oncology Reports)
Source: Gynecologic Oncology Reports - February 10, 2018 Category: OBGYN Source Type: research
Bartholin's abscess due to Dialister micraerophilus in a woman presenting with repetitive bartholinitis episodes.
Authors: Cobo F, Rodríguez-Granger J, Sampedro A, Navarro-Marí JM
PMID: 29397243 [PubMed - as supplied by publisher] (Source: Medecine et Maladies Infectieuses)
Source: Medecine et Maladies Infectieuses - February 6, 2018 Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
[Retroperitoneal Cellular Angiofibroma: A Rare Gynecological Entity].
We present the case of a woman with a heterogeneous tumor in the right adnexial region. At the surgery, a retroperitoneal tumor was excised and the histopathological tissue analysis revealed a cellular angiofibroma.
PMID: 29364801 [PubMed - in process] (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - January 26, 2018 Category: General Medicine Tags: Acta Med Port Source Type: research
Asymptomatic Bartholin Cyst: Evaluation With Multidetector Row Computed Tomography
Conclusions
High-attenuation Bartholin cysts are more common than previously thought and are usually seen in older women. The size and attenuation of Bartholin cysts show only minimal changes over time. (Source: Journal of Computer Assisted Tomography)
Source: Journal of Computer Assisted Tomography - January 1, 2018 Category: Radiology Tags: Abdominal Imaging Source Type: research
An unusually large ciliated cyst of the vulva in an adolescent patient
A 16-year-old presented with a painless, cystic left labial mass that had grown over 3 years (Figure 1). The differential diagnosis of a cystic vulvar mass includes a Bartholin duct cyst, epidermal inclusion cyst, mucinous or ciliated cyst, canal of Nuck cyst, Gartner duct cyst, or perineal hernia. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - December 22, 2017 Category: OBGYN Authors: Jessica A. Horne, Lena L. Merjanian, Adrian C. Balica Tags: Images in Gynecology Source Type: research
Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling
Transforming growth factor beta (TGFB) superfamily signaling is implicated in the development of sex cord-stromal tumors, a category of poorly defined gonadal tumors. The aim of this study was to determine pot... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - December 8, 2017 Category: Endocrinology Authors: Yang Gao, Xin Fang, David F. Vincent, David W. Threadgill, Laurent Bartholin and Qinglei Li Tags: Research Source Type: research
Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling.
CONCLUSIONS: These results reinforce the role of constitutively active TGFBR1 in promoting ovarian tumorigenesis in mice. The mouse model created in this study may be further exploited to define the cellular and molecular mechanisms of TGFB/activin downstream signaling in granulosa cell tumor development. Future studies are needed to test whether activation of TGFB/activin signaling contributes to the development of human granulosa cell tumors.
PMID: 29221447 [PubMed - in process] (Source: Reproductive Biology)
Source: Reproductive Biology - December 8, 2017 Category: Reproduction Medicine Authors: Gao Y, Fang X, Vincent DF, Threadgill DW, Bartholin L, Li Q Tags: Reprod Biol Endocrinol Source Type: research
Transarterial Embolization of a Bartholin Cyst Prior to Resection
Publication date: Available online 28 November 2017 Source:Journal of Minimally Invasive Gynecology Author(s): Joshua Cornman-Homonoff, Nigel Pereira, Tamatha B. Fenster, Marc H. Schiffman (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - December 5, 2017 Category: OBGYN Source Type: research
