18. Case of an adolescent girl with familial vulvar leiomyoma
While uterine leiomyomas remain a common occurrence affecting nearly 30% of adult women above 35yo, leiomyomas can arise anywhere smooth muscle cells are located in the body. Vulvar leiomyomas are a particularly rare diagnosis, often misdiagnosed as Bartholin gland cyst, comprising 0.07% of vulvar tumors, and thought to arise from smooth muscle within the round ligament, erectile tissue, and dartos muscle. Even more rare is the presentation of vulvar leiomyoma in the adolescent population and family history of vulvar leiomyoma. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Madeline Ross, Charlene Dekonenko, Rebecca Rentea, Tazim Dowlut-McElroy Source Type: research

Symptomatic Vaginal Masses Mimicking Prolapse: Varied Clinical Course, Diagnosis and Their Management
ConclusionVaginal masses are rare and often asymptomatic, but may present with varied clinical symptoms. They can be managed conservatively and surgically with good outcome. Follow-up is very essential to understand different clinical symptoms of vaginal masses. (Source: The Journal of Obstetrics and Gynecology of India)
Source: The Journal of Obstetrics and Gynecology of India - March 25, 2024 Category: OBGYN Source Type: research

Vaginal bulge is not always prolapse; could be a cyst
34yo G0 referred to Urogynecology for a vaginal bulge and occasional dyspareunia. On the exam she had a 4 cm anterior vaginal cystic mass without pelvic organ prolapse. The differential diagnosis for benign vaginal cysts is broad including M üllerian or Gartner’s (mesonephric) ducts, Skene’s, Bartholin gland, epidermal inclusion, or endometriotic cysts, adenosis, or urethral diverticulum. Vaginal cysts may present with or without symptoms. Most are secondary to embryological remnants or trauma. Müllerian ducts form the fallopian t ubes, broad ligament, uterus, cervix and upper part of the vagina. (Source: American Jo...
Source: American Journal of Obstetrics and Gynecology - March 21, 2024 Category: OBGYN Authors: A Trikhacheva, K Dengler, T Murdock, D Gruber Source Type: research

Vulvar Cancer, Version 3.2024, NCCN Clinical Practice Guidelines in Oncology
J Natl Compr Canc Netw. 2024 Mar;22(2):117-135. doi: 10.6004/jnccn.2024.0013.ABSTRACTVulvar cancer is annually diagnosed in an estimated 6,470 individuals and the vast majority are histologically squamous cell carcinomas. Vulvar cancer accounts for 5% to 8% of gynecologic malignancies. Known risk factors for vulvar cancer include increasing age, infection with human papillomavirus, cigarette smoking, inflammatory conditions affecting the vulva, and immunodeficiency. Most vulvar neoplasias are diagnosed at early stages. Rarer histologies exist and include melanoma, extramammary Paget's disease, Bartholin gland adenocarcinom...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - March 19, 2024 Category: Cancer & Oncology Authors: Nadeem R Abu-Rustum Catheryn M Yashar Rebecca Arend Emma Barber Kristin Bradley Rebecca Brooks Susana M Campos Junzo Chino Hye Sook Chon Marta Ann Crispens Shari Damast Christine M Fisher Peter Frederick David K Gaffney Stephanie Gaillard Robert Giuntoli Source Type: research