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Molecular typing of clinical multidrug-resistant Klebsiella pneumoniae isolates
CONCLUSION: Both PCR-typing methods with phenotypic patterns can be useful for the epidemiological typing of K. pneumoniae isolates with the highest performance in discriminating isolates.PMID:38478145 | DOI:10.1007/s11033-024-09278-y (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 13, 2024 Category: Molecular Biology Authors: Mehdi Kashefieh Habib Zeighami Hossein Samadi Kafil Pourya Gholizadeh Javid Sadeghi Mohammad Hossein Soroush Barhaghi Hamed Ebrahimzadeh Leylabadlo Reza Ghotaslou Source Type: research

Serotype distribution and antimicrobial resistance of pediatric Streptococcus pneumoniae isolated from inpatients and outpatients at Beijing Children's Hospital
CONCLUSIONS: Pneumococcal vaccine-related serotypes are prevalent among both inpatients and outpatients, especially among inpatients, who exhibit more severe antibiotic resistance. Therefore, universal immunization with PCV13 would decrease the hospitalization rate due to S. pneumoniae and the antibiotic resistance rate of S. pneumoniae.PMID:38471654 | DOI:10.1016/j.bjid.2024.103734 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - March 12, 2024 Category: Infectious Diseases Authors: Shuang Lyu Wei Shi Fang Dong Bao Ping Xu Gang Liu Quan Wang Kai Hu Yao Yong Hong Yang Source Type: research

A rare urinary tract infection of multidrug-resistant Chryseobacterium urinae sp. nov. isolated from a diabetic, non-catheterized patient
This report underscores the vital importance of elucidating susceptibility patterns of rare pathogens like Chryseobacterium, particularly in immunocompromised individuals. It advocates for further analyses to understand the functional significance of identified genes and their implications in treatment and pathogenesis.PMID:38466448 | DOI:10.1007/s00203-024-03881-0 (Source: Cell Research)
Source: Cell Research - March 11, 2024 Category: Cytology Authors: Agrima Bhatt Sujata Pujari Shailesh Mantri Kiran Kirdat Lucky Thakkar Reshma Poojary Sunil Kuyare Kritika Patil Amit Yadav Source Type: research

A rare urinary tract infection of multidrug-resistant Chryseobacterium urinae sp. nov. isolated from a diabetic, non-catheterized patient
This report underscores the vital importance of elucidating susceptibility patterns of rare pathogens like Chryseobacterium, particularly in immunocompromised individuals. It advocates for further analyses to understand the functional significance of identified genes and their implications in treatment and pathogenesis.PMID:38466448 | DOI:10.1007/s00203-024-03881-0 (Source: Archives of Microbiology)
Source: Archives of Microbiology - March 11, 2024 Category: Microbiology Authors: Agrima Bhatt Sujata Pujari Shailesh Mantri Kiran Kirdat Lucky Thakkar Reshma Poojary Sunil Kuyare Kritika Patil Amit Yadav Source Type: research

KPC-2 and VIM-1 producing Klebsiella pneumoniae ST39 high-risk clone isolated from a clinical sample in Volos, Greece
In this study, we analyzed A165 strain K. pneumoniae ST39 isolated from a blood culture in November 2020. Whole-genome sequencing (WGS) was performed using Ion Torrent Platform, and resistance genes, virulence determinants, capsular types, insertion sequences, phage regions, and clustered regularly interspaced palindromic repeats (CRISPR) regions were detected by bioinformatic analysis. The molecular characterization revealed antimicrobial resistance genes, including sul2 for sulfamethoxazole; dfrA1 for trimethoprim; blaVIM-1 and blaKPC-2 for carbapenems; aac(6')-II for aminoglycosides; fosA for fosfomycin and aad1 for str...
Source: Acta Microbiologica et Immunologica Hungarica - March 7, 2024 Category: Microbiology Authors: Maria Chatzidimitriou Pandora Tsolakidou Chatzivasileiou Panagiota Eleni Mylona Stella Mitka Source Type: research

Antimicrobial resistance and genomic investigation of Salmonella isolated from retail foods in Guizhou, China
IntroductionSalmonella is a major foodborne pathogen worldwide that causes severe morbidity and mortality. It is mainly caused by consuming contaminated food, with retail food considered the primary source.MethodsIn Guizhou, China, 102 Salmonella strains isolated from 2016 to 2021 underwent phenotypic antimicrobial resistance testing and whole-genome sequencing (WGS) to understand Salmonella diversity, including serotypes, sequencing types (STs), antimicrobial genes, virulence genes, plasmid types, multi-locus sequence types (MLST), and core genome MLST (cgMLST).Results and discussionS.Typhimurium was the dominant serotype...
Source: Frontiers in Microbiology - March 6, 2024 Category: Microbiology Source Type: research

Unusual Finding in a Boy with Recurrent Epididymo-Orchitis and Normal External Genitalia
A 1-year-old boy with Down syndrome presented to the emergency department due to his third episode of epididymo-orchitis (EO). He was previously treated with trimethoprim-sulfamethoxazole. His parents reported irritability, fever, and inflammation of the right testis. Scrotal examination revealed an enlarged, tender right testicle without overlying skin changes, hypospadias, or cryptorchidism. Testicular ultrasound showed signs suggestive of right EO, and urine culture was positive for Pseudomonas Aeruginosa. (Source: Urology)
Source: Urology - March 6, 2024 Category: Urology & Nephrology Authors: Julio C ésar Moreno-Alfonso, María San Basilio Berenguer, Borja Nava, Virginia Amesty, Roberto Lobato, María José Martínez Urrutia, Pedro López Pereira, Susana Rivas Vila Source Type: research

Antimicrobial resistance and public and animal health risks associated with pathogenic Escherichia coli isolated from calves
Comp Immunol Microbiol Infect Dis. 2024 Feb 19;107:102149. doi: 10.1016/j.cimid.2024.102149. Online ahead of print.ABSTRACTWe aimed to determine the antimicrobial susceptibility profile of pathogenic Escherichia coli strains isolated from fecal samples of calves and buffalo calves (2008-2013), in Minas Gerais, Brazil, as well as the frequency of O157 gene and strains carrying extended-spectrum beta-lactamases (ESBL) and mobile colistin resistance (mcr) genes. E. coli strains (n=518) were tested for susceptibility against ten antimicrobials. Tetracycline was the antimicrobial with the highest resistance rate (382/518), foll...
Source: Comparative immunology, microbiology and infectious diseases. - March 5, 2024 Category: Allergy & Immunology Authors: Dirc éia Aparecida da Costa Custódio Carine Rodrigues Pereira Maysa Serpa Gon çalves Anna Cec ília Trolesi Reis Borges Costa Pedro Felipe Rodrigues de Oliveira Bruna Henrique Pinto da Silva Giovanna Botelho Carneiro Fernanda Morcatti Coura Andrey Pere Source Type: research

Combination of trimethoprim-sulfamethoxazole and clindamycin in the treatment of relapsing toxoplasmic encephalitis
J Microbiol Immunol Infect. 2024 Feb 28:S1684-1182(24)00045-8. doi: 10.1016/j.jmii.2024.02.008. Online ahead of print.NO ABSTRACTPMID:38443217 | DOI:10.1016/j.jmii.2024.02.008 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - March 5, 2024 Category: Microbiology Authors: Shih-Wen Ting Jien-Wei Liu Source Type: research