Antibiotic-resistant urinary tract infections are on the rise
There is a global crisis of antibiotic resistance, and urinary tract infections (UTIs) may be the canary in the coal mine. UTIs are one of the most common types of infections; at least one in two women and one in 10 men will experience a UTI in their lifetime.
Like many human infections, UTIs are usually caused by bacteria living on or in our bodies, and require treatment with antibiotics. What’s alarming the medical community now is that UTIs are becoming ever harder to treat with common antibiotics.
Antibiotic overuse leads to antibiotic resistance
At some point, most people have taken a course of trimethoprim/sulfamet...
Source: Harvard Health Blog - October 14, 2019 Category: Consumer Health News Authors: Lisa Bebell, MD Tags: Drugs and Supplements Health Infectious diseases Kidney and urinary tract Women's Health Source Type: blogs
Co-trimoxazole
CLASS 2 antibiotics (sulfamethoxazole and trimethoprim) MECHANISM OF ACTION sulfamethoxazole -> inhibits bacterial synthesis of dihydrofolic acid trimethoprim -> blocks production of tetrahydrofolic acid -> blocks two consecutive steps in the biosythesis of nucleic acids and proteins essential to bacteria. PHARMACEUTICS PO – each tablet = 80mg trimethoprim and 400mg sulfamethoxazole IV – 5mL contains […]
The post Co-trimoxazole appeared first on Life in the Fast Lane • LITFL • Medical Blog. (Source: Life in the Fast Lane)
Source: Life in the Fast Lane - April 13, 2019 Category: Emergency Medicine Authors: Hamish Cadogan Tags: CCC Source Type: blogs
Pediatric Conjunctivitis a Simple Diagnosis Until It Isn’t
Conjunctivitis is a common condition and easy enough to treat, but several uncommon conjunctivitis syndromes require more care and should not be missed.Conjunctivitis is either infectious (viral or bacterial) or noninfectious (allergic or nonallergic). Viral infections are more common in adults, bacterial ones in children, usually caused by Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Adults tend to have more S. aureus infections, while the other pathogens are more common in children. An adenovirus is typically responsible for viral-associated infections in conjunct...
Source: M2E Too! Mellick's Multimedia EduBlog - March 1, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
Acute Angle Closure: Mastering Tonometry
Identifying and managing disease often requires the delicate and skillful use of temperamental emergency department machinery. The ability to apply these may appropriately help determine a difficult diagnosis.Glaucoma, we all know, can cause blindness, and acute narrow angle glaucoma refers to the angles within the eye that are not as wide and open as normal. People with acute angle glaucoma have abnormal anatomy within the eye where the angle changes as the eye is dilated. This can cause blockages of fluid drainage from the anterior to posterior changes resulting in increased intraocular pressure. It ca lead to acute a...
Source: The Procedural Pause - November 9, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
MKSAP: 35-year-old woman is evaluated for intermittent fever
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 35-year-old woman is evaluated for intermittent fever, sweats, fatigue, and dull midchest pain of 2 weeks’ duration. Medical history is significant for liver transplantation 6 months ago for primary biliary cirrhosis; she was seronegative for cytomegalovirus and Epstein-Barr virus, and her donor was positive for both. Results of pretransplant testing for tuberculosis were negative. She received valganciclovir prophylaxis for 3 months after transplantation. Medications are tacrolimus, prednisone, mycophen...
Source: Kevin, M.D. - Medical Weblog - May 12, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Allergies & Immunology Infectious Disease Source Type: blogs
MKSAP: 32-year-old man with a rash on his face and midchest
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 32-year-old man is evaluated for a 2-week history of a rash on his face and midchest. He describes the rash as consisting of small, reddish “lumps” that are intensely itchy; they develop and begin to resolve with development of new lesions. He otherwise feels well. Medical history is significant for a recent diagnosis of HIV infection. Medications are tenofovir, emtricitabine, efavirenz, and trimethoprim-sulfamethoxazole. On physical examination, vital signs are normal.
The patient has 1- to 3-mm papules a...
Source: Kevin, M.D. - Medical Weblog - November 11, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Dermatology Infectious Disease Source Type: blogs
MKSAP: 20-year-old male college student with a superficial skin infection
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 20-year-old male college student on the wrestling team is evaluated for a superficial skin infection. He has a history of several episodes of folliculitis and furunculosis over the past year that has required systemic treatment. His recurrent infections were treated with various oral antibiotics, including cephalexin, clindamycin, and trimethoprim-sulfamethoxazole. He currently takes no medications, has no drug allergies, and is otherwise in good health.
On physical examination, vital signs are normal. There a...
Source: Kevin, M.D. - Medical Weblog - July 15, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Infectious disease Source Type: blogs
Celiac Disease: A Serious, Life-Changing Condition
I met Paul Graham courtesy of one of his essays. Then, we talked by phone and I read – no devoured – his book, In Memory of Bread: A Memoir. Pardon the pun. Paul is a professor of English Department at St. Lawrence University in Canton, NY and on July 1 becomes Department Chair. He focuses on fiction and non-fiction creative writing and lives with his wife, Bec and their German shepherds.
Paul, your book is the best description I’ve read about the challenges of being diagnosed with celiac. Can you summarize what happened? Given your experience, what recommendations would you have for clinicians? Should celiac be su...
Source: Disruptive Women in Health Care - June 5, 2017 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: Uncategorized Source Type: blogs
Welcome to my World: Perpetual Alarm Fatigue
By HANS DUVEFELT, MD
Part of a series on primary care challenges and their solutions.
I missed a drug interaction warning the other day when I prescribed a sulfa antibiotic to Barton, a COPD patient who is also taking dofetilide, an uncommon antiarrhythmic.
The pharmacy called me to question the prescription, and I quickly changed it to a cephalosporin.
The big red warning had popped up on my computer screen, but I x-ed it away with my right thumb on the trackball without reading the warning. Quite honestly, I am so used to getting irrelevant warnings that it has become a reflex to bring the cursor to the spot where I can ...
Source: The Health Care Blog - August 15, 2016 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs
MKSAP: 32-year-old man with a rash on his face and midchest
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 32-year-old man is evaluated for a 2-week history of a rash on his face and midchest. He describes the rash as consisting of small, reddish “lumps” that are intensely itchy; they develop and begin to resolve with development of new lesions. He otherwise feels well.
Medical history is significant for a recent diagnosis of HIV infection. Medications are tenofovir, emtricitabine, efavirenz, and trimethoprim-sulfamethoxazole. On physical examination, vital signs are normal. The patient has 1- to 3-mm p...
Source: Kevin, M.D. - Medical Weblog - June 4, 2016 Category: Journals (General) Authors: mksap Tags: Conditions Dermatology Source Type: blogs
LITFL Review 226
Welcome to the 226th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chuck of FOAM.
The Most Fair Dinkum Ripper Beauts of the Week
Core EM features a surprisingly valuable video this week on how to set up an arterial line. A great post teaching the logistics of resuscitation. [AS]
Here’s a really great case, with even better images. Become more aware of this life-threaten...
Source: Life in the Fast Lane - April 3, 2016 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs
Research and Reviews in the Fastlane 127
This study didn’t look at simple abscesses but rather at ones that most clinicians would have given antibiotics to and in spite of that, they found only a relatively modest benefit. Despite the headline, this is NOT practice changing.
Recommended by: Anand Swaminathan
Further reading: Are Antibiotics Back in Favor for Abscesses? (EM Literature of Note), Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscesses? (R.E.B.E.L. EM)
The Best of the Rest
Emergency Medicine
Martin SP, et al. Double-dorsal single-volar digital subcutaneous anaesthetic injection for finger injuries in the emergency department: A r...
Source: Life in the Fast Lane - March 23, 2016 Category: Emergency Medicine Authors: Jeremy Fried Tags: Airway Anaesthetics Emergency Medicine Infectious Disease Neurology R&R in the FASTLANE Resuscitation EBM Education literature recommendations research and reviews Source Type: blogs
LITFL Review 222
Welcome to the 222nd LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chuck of FOAM.
The Most Fair Dinkum Ripper Beauts of the Week
Josh Farkas explains his top 10 issues/problems with the new Sepsis-3 definitions. [SR]
The Best of #FOAMed Emergency Medicine
First 10 EM drops their articles of the month as February comes to a close. [AS]
Cameron Berg discusses another way ...
Source: Life in the Fast Lane - March 6, 2016 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs
The Limitations of Healthcare Science
By SIDNEY LE
Every once in awhile on the wards, one of the attending physicians will approach me and ask me to perform a literature review on a particular clinical question. It might be a question like “What does the evidence say about how long should Bactrim should be given for a UTI?” or “Which is more effective in the management of atrial fibrillation, rate control or rhythm control?” A chill usually runs down my spine, like that feeling one gets when a cop siren wails from behind while one is driving. But thankfully, summarizing what we know about a subject is actually a pretty formulaic exercise, involving a...
Source: The Health Care Blog - November 21, 2015 Category: Consumer Health News Authors: Simon Nath Tags: THCB Healthcare Science Journals Negative Studies Population Health Publication Research Sidney Le Source Type: blogs
Funtabulously Frivolous Friday Five 122
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia…introducing Funtabulously Frivolous Friday Five 122
Question 1
What is a Clay-shoveler’s fracture and how do you get one?
+ Reveal the Funtabulous Answer
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Fracture through the spinous process of a vertebra occurring at any of the lower cervical or upper thoracic vertebrae, classically at C6 or C7.
Originally described in Australia associated with (no prizes for...
Source: Life in the Fast Lane - October 23, 2015 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five adrenal crisis adrenal insufficiency botulism clay shoveler's fracture erythema multiforme rhabdomyolysis Source Type: blogs
