Serotype diversity and antimicrobial susceptibility profiles of Actinobacillus pleuropneumoniae isolated in Italian pig farms from 2015 to 2022
AbstractActinobacillus pleuropneumoniae (APP) is a bacterium frequently associated with porcine pleuropneumonia. The acute form of the disease is highly contagious and often fatal, resulting in significant economic losses for pig farmers. Serotype diversity and antimicrobial resistance (AMR) of APP strains circulating in north Italian farms from 2015 to 2022 were evaluated retrospectively to investigate APP epidemiology in the area. A total of 572 strains isolated from outbreaks occurring in 337 different swine farms were analysed. The majority of isolates belonged to serotypes 9/11 (39.2%) and 2 (28.1%) and serotype diver...
Source: Veterinary Research - April 9, 2024 Category: Veterinary Research Source Type: research

Antibiotics efficacy in clinical and microbiological cure of uncomplicated urinary tract infection: a systematic review and network meta-analysis
ConclusionThe network meta-analysis demonstrated that Fosfomycin is the most effective antibiotic in treating uncomplicated UTIs with respect to clinical cure, microbiological cure, and adverse events profile. (Source: World Journal of Urology)
Source: World Journal of Urology - April 8, 2024 Category: Urology & Nephrology Source Type: research

Antibiotic resistance profiling and phylotyping of human-diarrheagenic Escherichia coli pathotypes detected from diarrheic and non-diarrheic calves in Iran
CONCLUSIONS: The prevalence of VG-positive E. coli isolates was higher in healthy calves compared to diarrheic cases. AR was widespread among VG-positive isolates. These findings suggest that calves may serve as potential reservoirs of antimicrobial-resistant hybrid pathotypes of E. coli.PMID:38581525 | DOI:10.1007/s11033-024-09494-6 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 6, 2024 Category: Molecular Biology Authors: Zahede Naderi Reza Ghanbarpour Maziar Jajarmi Sanaz Dehdashti Mahboube Bagheri Neda Eskandarzade Parvin Mohseni Hesam Alizade Source Type: research

Antibiotic resistance profiling and phylotyping of human-diarrheagenic Escherichia coli pathotypes detected from diarrheic and non-diarrheic calves in Iran
CONCLUSIONS: The prevalence of VG-positive E. coli isolates was higher in healthy calves compared to diarrheic cases. AR was widespread among VG-positive isolates. These findings suggest that calves may serve as potential reservoirs of antimicrobial-resistant hybrid pathotypes of E. coli.PMID:38581525 | DOI:10.1007/s11033-024-09494-6 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 6, 2024 Category: Molecular Biology Authors: Zahede Naderi Reza Ghanbarpour Maziar Jajarmi Sanaz Dehdashti Mahboube Bagheri Neda Eskandarzade Parvin Mohseni Hesam Alizade Source Type: research

Prolonged suppressive antibiotic therapy for inferior vena cava filter infection following emphysematous pyelonephritis and cystitis: a case report
CONCLUSION: Infections of implanted devices, such as IVC filters, secondary to severe infections can cause persistent bacteremia. PSAT may be an alternative option to treat IVC filter infection, when the IVC filter is considered difficult to remove.PMID:38576969 | PMC:PMC10990323 | DOI:10.1097/MS9.0000000000001886 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Yasuhiro Suzuki Akira Kuriyama Source Type: research

Antimicrobial Resistance Patterns in Patients with Vaginal Discharge: A 2019-2022 Analysis at the National Health Laboratory in Eritrea
CONCLUSION: Most gram-negative bacteria displayed higher resistance of >45% to ampicillin, trimethoprim-sulfamethoxazole, and tetracycline. Among gram-positive bacteria, a higher resistance rate with ampicillin, trimethoprim-sulfamethoxazole, tetracycline, oxacillin, vancomycin, and penicillin G was recorded. S. aureus showed no resistance to rifampicin and clindamycin, and Strep. spp. indicated 100% resistance to rifampicin and vancomycin. This study highlights critical gaps and areas for further exploration. Expanding the spectrum of antibiotics tested and investigating underlying multidrug resistance mechanisms would...
Source: Biomed Res - April 5, 2024 Category: Research Authors: Khalid Hussein Berhe Tesfai Okbu Frezgi Hagos Hayelom Yosan Gebremeskel Azania Werede Hailemichael Gebremariam Fitsum Kibreab Mohammed Elfatih Hamida Source Type: research

Prolonged suppressive antibiotic therapy for inferior vena cava filter infection following emphysematous pyelonephritis and cystitis: a case report
CONCLUSION: Infections of implanted devices, such as IVC filters, secondary to severe infections can cause persistent bacteremia. PSAT may be an alternative option to treat IVC filter infection, when the IVC filter is considered difficult to remove.PMID:38576969 | PMC:PMC10990323 | DOI:10.1097/MS9.0000000000001886 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Yasuhiro Suzuki Akira Kuriyama Source Type: research

Antimicrobial Resistance Patterns in Patients with Vaginal Discharge: A 2019-2022 Analysis at the National Health Laboratory in Eritrea
CONCLUSION: Most gram-negative bacteria displayed higher resistance of >45% to ampicillin, trimethoprim-sulfamethoxazole, and tetracycline. Among gram-positive bacteria, a higher resistance rate with ampicillin, trimethoprim-sulfamethoxazole, tetracycline, oxacillin, vancomycin, and penicillin G was recorded. S. aureus showed no resistance to rifampicin and clindamycin, and Strep. spp. indicated 100% resistance to rifampicin and vancomycin. This study highlights critical gaps and areas for further exploration. Expanding the spectrum of antibiotics tested and investigating underlying multidrug resistance mechanisms would...
Source: Biomed Res - April 5, 2024 Category: Research Authors: Khalid Hussein Berhe Tesfai Okbu Frezgi Hagos Hayelom Yosan Gebremeskel Azania Werede Hailemichael Gebremariam Fitsum Kibreab Mohammed Elfatih Hamida Source Type: research

Prolonged suppressive antibiotic therapy for inferior vena cava filter infection following emphysematous pyelonephritis and cystitis: a case report
CONCLUSION: Infections of implanted devices, such as IVC filters, secondary to severe infections can cause persistent bacteremia. PSAT may be an alternative option to treat IVC filter infection, when the IVC filter is considered difficult to remove.PMID:38576969 | PMC:PMC10990323 | DOI:10.1097/MS9.0000000000001886 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Yasuhiro Suzuki Akira Kuriyama Source Type: research

Antimicrobial Resistance Patterns in Patients with Vaginal Discharge: A 2019-2022 Analysis at the National Health Laboratory in Eritrea
CONCLUSION: Most gram-negative bacteria displayed higher resistance of >45% to ampicillin, trimethoprim-sulfamethoxazole, and tetracycline. Among gram-positive bacteria, a higher resistance rate with ampicillin, trimethoprim-sulfamethoxazole, tetracycline, oxacillin, vancomycin, and penicillin G was recorded. S. aureus showed no resistance to rifampicin and clindamycin, and Strep. spp. indicated 100% resistance to rifampicin and vancomycin. This study highlights critical gaps and areas for further exploration. Expanding the spectrum of antibiotics tested and investigating underlying multidrug resistance mechanisms would...
Source: Biomed Res - April 5, 2024 Category: Research Authors: Khalid Hussein Berhe Tesfai Okbu Frezgi Hagos Hayelom Yosan Gebremeskel Azania Werede Hailemichael Gebremariam Fitsum Kibreab Mohammed Elfatih Hamida Source Type: research

Antimicrobial Resistance Patterns in Patients with Vaginal Discharge: A 2019-2022 Analysis at the National Health Laboratory in Eritrea
CONCLUSION: Most gram-negative bacteria displayed higher resistance of >45% to ampicillin, trimethoprim-sulfamethoxazole, and tetracycline. Among gram-positive bacteria, a higher resistance rate with ampicillin, trimethoprim-sulfamethoxazole, tetracycline, oxacillin, vancomycin, and penicillin G was recorded. S. aureus showed no resistance to rifampicin and clindamycin, and Strep. spp. indicated 100% resistance to rifampicin and vancomycin. This study highlights critical gaps and areas for further exploration. Expanding the spectrum of antibiotics tested and investigating underlying multidrug resistance mechanisms would...
Source: Biomed Res - April 5, 2024 Category: Research Authors: Khalid Hussein Berhe Tesfai Okbu Frezgi Hagos Hayelom Yosan Gebremeskel Azania Werede Hailemichael Gebremariam Fitsum Kibreab Mohammed Elfatih Hamida Source Type: research

Analysis of Clinical, Immunological and Molecular Features of Leukocyte Adhesion Deficiency Type I in Egyptian Children
ConclusionThis study highlights the importance of early diagnosis and distribution ofITG ß2 gene mutation in Egyptian children. Further molecular studies, however, remain a challenging necessity for better disease characterization in the region. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - April 5, 2024 Category: Allergy & Immunology Source Type: research

Pathogenic characteristics of an aggregated diarrhea event caused by < i > Plesiomonas shigelloides < /i > from stream
This study aimed to investigate the cause of a foodborne disease outbreak in Huzhou on August 14, 2023. Multiple enteropathogens were detected using FilmArray, and the pathogen was subsequently isolated and cultured from anal swabs of the cases and stream water. The isolated strains were identifie d using VITEK MS, and antimicrobial susceptibility test, pulsed field gel electrophoresis (PFGE) molecular typing, and whole genome sequencing (WGS) were performed on the isolates ofPlesiomonas shigelloides. Gene annotation and sequence alignment were used to analyze the virulence genes and drug resistance genes of the strains. A...
Source: PLoS One - April 4, 2024 Category: Biomedical Science Authors: Peng Zhang Source Type: research

Increased Risk of Nocardia Infection with Atovaquone Prophylaxis in Cardiac Transplant Patients: A Critical Analysis
Purpose: Prophylactic measures are essential to minimize the risk of opportunistic infections in transplant recipients. Traditionally, sulfamethoxazole-trimethoprim (Bactrim) has been the preferred prophylactic agent for pneumocystis jirovecii pneumonia (PJP). However, use comes with risk of hyperkalemia and caution in patients with kidney impairment or sulfa allergy. Use of alternative agents, such as atovaquone and dapsone, may not offer as broad of protection against other infections. Nocardia infections are a rare but serious complication in heart transplant recipients. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: A. Robbins, J. Conway, R. Singh, Source Type: research

The Prevalence and Antimicrobial Susceptibility of Methicillin-Resistant Staphylococcus aureus Before and After the COVID-19 Pandemic in a Tertiary Saudi Hospital
CONCLUSION: It was concluded that the prevalence rates of MRSA have not increased in 2020 when compared to 2019. Vancomycin, linezolid, trimethoprim-sulfamethoxazole, and doxycycline remain susceptible to the positive collected MRSA strains. There was no significant difference between the prevalence and antimicrobial resistance rates of MRSA between 2019 and 2020. Continued research efforts are needed to address this persistent public health threat. Strategies to control the spread of MRSA should include early detection of MRSA and surveillance, even during pandemics.PMID:38529437 | PMC:PMC10962010 | DOI:10.7759/cureus.548...
Source: Cancer Control - March 26, 2024 Category: Cancer & Oncology Authors: Omar B Ahmed Fayez S Bahwerth Radi Alsafi Eman A Elsebaei Gamal T Ebid Abdulrhaman Theyab Hamza Assaggaf Source Type: research