Potential and prospects for utilization of avocado by-products in integrated biorefineries
Bioresour Technol. 2022 Sep 26:128034. doi: 10.1016/j.biortech.2022.128034. Online ahead of print.ABSTRACTThe industrial processing of avocado to extract oil, and produce guacamole or sauces generates enormous quantities of peels and seeds (around 2 million tons worldwide in 2019) without commercially valuable applications. However, various studies have suggested the presence of a wide range of interesting compounds in the composition of these by-products. This review depicts a thorough outline of the capacity of avocado residues to be converted into a portfolio of commodities that can be employed in sectors such as the fo...
Source: Bioresource Technology - September 29, 2022 Category: Biotechnology Authors: Beatriz Rodr íguez-Martínez Aloia Roman í Gemma Eibes Gil Garrote Beatriz Gull ón Pablo G Del R ío Source Type: research

Identification of antifungal compounds from avocado rhizobacteria (Bacillus spp.) against Fusarium spp., by a bioassay-guided  fractionation approach
Chem Biodivers. 2022 Sep 23. doi: 10.1002/cbdv.202200687. Online ahead of print.ABSTRACTAntimicrobial compounds produced by bacteria have been increasingly acknowledged as an important resource for the control of phytopathogens. In this work, through a bioassay-guided fractionation approach we identify antifungal metabolites produced by two avocado rhizobacteria (INECOL-4742 and INECOL-5927) both members of the Bacillus subtilis/B. amyloliquefaciens species complex, against Fusarium solani and F. kuroshium, causal agent of Fusarium dieback in avocado and other hosts. The n-butanol (n-BuOH) organic extract from INECOL-4742 ...
Source: Chemistry and Biodiversity - September 23, 2022 Category: Biochemistry Authors: Edgar Guevara-Avenda ño Mayra Lizette P érez-Molina Juan Luis Monribot-Villanueva Elvis Marian Cortazar-Murillo M ónica Ramírez-Vázquez Fr édérique Reverchon Jos é A Guerrero-Analco Source Type: research

Identification of antifungal compounds from avocado rhizobacteria (Bacillus spp.) against Fusarium spp., by a bioassay-guided  fractionation approach
Chem Biodivers. 2022 Sep 23. doi: 10.1002/cbdv.202200687. Online ahead of print.ABSTRACTAntimicrobial compounds produced by bacteria have been increasingly acknowledged as an important resource for the control of phytopathogens. In this work, through a bioassay-guided fractionation approach we identify antifungal metabolites produced by two avocado rhizobacteria (INECOL-4742 and INECOL-5927) both members of the Bacillus subtilis/B. amyloliquefaciens species complex, against Fusarium solani and F. kuroshium, causal agent of Fusarium dieback in avocado and other hosts. The n-butanol (n-BuOH) organic extract from INECOL-4742 ...
Source: Chemistry and Biodiversity - September 23, 2022 Category: Biochemistry Authors: Edgar Guevara-Avenda ño Mayra Lizette P érez-Molina Juan Luis Monribot-Villanueva Elvis Marian Cortazar-Murillo M ónica Ramírez-Vázquez Fr édérique Reverchon Jos é A Guerrero-Analco Source Type: research

Oligomeric Proanthocyanidin Complex from Avocado Seed as A Promising α-glucosidase Inhibitor: Characteristics and Mechanisms
In this study, through bioassay-guided isolation of the main α-glucosidase inhibitors in avocado seed, we discovered the major α-glucosidase inhibitor to be avocado seed oligomeric proanthocyanidin complex (ASOPC). Thiolysis and UPLC-DAD-HRESIMS showed the presence of A- and B-type procyanidins, and B-type propelargonidin with (epi)afzelechin as extension unit. Mean degree of polymerization (mDP) of ASOPC was calculated as 7.3±1. Furthermore, ASOPC appeared to be a strong, reversible, competitive inhibitor of α-glucosidase, with IC50 value of 0.1 µg/mL, which was significantly lower than Acarbose (IC50 = 75.6 µg/mL),...
Source: Planta Medica - September 22, 2022 Category: Drugs & Pharmacology Authors: Nguyen, Thien Huu Amen, Yhiya Othman, Ahmed Wang, Dongmei Masako, Matsumoto Maki, Nagata Shimizu, Kuniyoshi Tags: Original Papers Source Type: research

Acetogenin-induced fibrotic heart disease from avocado (Persea americana, Lauraceae) poisoning in horses
Toxicon. 2022 Sep 16:S0041-0101(22)00266-5. doi: 10.1016/j.toxicon.2022.09.007. Online ahead of print.ABSTRACTPoisoning by avocado (Persea americana) has been confirmed in sheep, goats, dogs, rabbits and ostriches. The clinical signs and lesions are attributed to the acetogenin, persin. Little is known regarding the epidemiology, clinical signs, lesions and therapy caused by acetogenin-induced heart damage. During the two-year study, we investigated a horse farm with six horses that often fed themselves with P. americana leaves or mature fruit pulp and skin on the ground. Two horses died, and one underwent necropsy, histop...
Source: Toxicon - September 19, 2022 Category: Toxicology Authors: Marina S Freitas Asheley H B Pereira Gabriela O Pereira Islaine S Menezes Alessandra R Lucena Carolina R F Almeida Erinaldo G Pereira Leandro A Santos Luiz R S Tozin Fl ávio M Alves Arthur L Macedo Denise B Silva Daniel G Ubiali Source Type: research

Acetogenin-induced fibrotic heart disease from avocado (Persea americana, Lauraceae) poisoning in horses
Toxicon. 2022 Sep 16:S0041-0101(22)00266-5. doi: 10.1016/j.toxicon.2022.09.007. Online ahead of print.ABSTRACTPoisoning by avocado (Persea americana) has been confirmed in sheep, goats, dogs, rabbits and ostriches. The clinical signs and lesions are attributed to the acetogenin, persin. Little is known regarding the epidemiology, clinical signs, lesions and therapy caused by acetogenin-induced heart damage. During the two-year study, we investigated a horse farm with six horses that often fed themselves with P. americana leaves or mature fruit pulp and skin on the ground. Two horses died, and one underwent necropsy, histop...
Source: Toxicon - September 19, 2022 Category: Toxicology Authors: Marina S Freitas Asheley H B Pereira Gabriela O Pereira Islaine S Menezes Alessandra R Lucena Carolina R F Almeida Erinaldo G Pereira Leandro A Santos Luiz R S Tozin Fl ávio M Alves Arthur L Macedo Denise B Silva Daniel G Ubiali Source Type: research

Response Surface Methodology Applied to the Optimization of the Preparation of Antioxidant and Antidiabetic Extracts from < em > Phragmanthera capitata < /em > (Spreng.) Balle: Effect of Particle Size, Powder-to-Solvent Ratio, and Temperature
Evid Based Complement Alternat Med. 2022 Sep 1;2022:8397250. doi: 10.1155/2022/8397250. eCollection 2022.ABSTRACTPhragmanthera capitata is a medicinal plant used in traditional medicine to treat several diseases, including diabetes. Its antioxidant properties and inhibitory effects on enzyme-carbohydrate digestion activities have been demonstrated. The present study aimed to provide data that can contribute to rationalizing the preparation of antioxidant and antidiabetic extracts from this plant. P. capitata (whole plant) growing on Persea americana was harvested at the fruiting stage. A response surface design-type centra...
Source: Evidence-based Complementary and Alternative Medicine - September 12, 2022 Category: Complementary Medicine Authors: C ésaire Feudjio Guy Sedar Singor Njateng Mathilde Julie Klang Muhammad Arfat Yameen Muhammad Ahsan Khan Jules-Roger Kuiate Source Type: research

Comparative sub-cellular proteome analyses reveals metabolic differentiation and production of effector-like molecules in the dieback phytopathogen Phytophthora cinnamomi
This study highlights the differential metabolism and cellular processes between the sub-proteomes. Proteins associated with metabolism, nutrient transport and cellular proliferation were over represented in the mycelia. The zoospores have a specialised proteome showing increased energy generation geared towards motility. Candidate effectors and effector-like secreted proteins were also identified, which can be exploited for genetic resistance. This demonstrates a better understanding of the biology and pathogenicity of P. cinnamomi infection that can subsequently be used to develop effective methods of disease management....
Source: Journal of Proteomics - September 12, 2022 Category: Biochemistry Authors: Christina E Andronis Silke Jacques Richard Lipscombe Kar-Chun Tan Source Type: research

Response Surface Methodology Applied to the Optimization of the Preparation of Antioxidant and Antidiabetic Extracts from < em > Phragmanthera capitata < /em > (Spreng.) Balle: Effect of Particle Size, Powder-to-Solvent Ratio, and Temperature
Evid Based Complement Alternat Med. 2022 Sep 1;2022:8397250. doi: 10.1155/2022/8397250. eCollection 2022.ABSTRACTPhragmanthera capitata is a medicinal plant used in traditional medicine to treat several diseases, including diabetes. Its antioxidant properties and inhibitory effects on enzyme-carbohydrate digestion activities have been demonstrated. The present study aimed to provide data that can contribute to rationalizing the preparation of antioxidant and antidiabetic extracts from this plant. P. capitata (whole plant) growing on Persea americana was harvested at the fruiting stage. A response surface design-type centra...
Source: Evidence-based Complementary and Alternative Medicine - September 12, 2022 Category: Complementary Medicine Authors: C ésaire Feudjio Guy Sedar Singor Njateng Mathilde Julie Klang Muhammad Arfat Yameen Muhammad Ahsan Khan Jules-Roger Kuiate Source Type: research

Comparative sub-cellular proteome analyses reveals metabolic differentiation and production of effector-like molecules in the dieback phytopathogen Phytophthora cinnamomi
This study highlights the differential metabolism and cellular processes between the sub-proteomes. Proteins associated with metabolism, nutrient transport and cellular proliferation were over represented in the mycelia. The zoospores have a specialised proteome showing increased energy generation geared towards motility. Candidate effectors and effector-like secreted proteins were also identified, which can be exploited for genetic resistance. This demonstrates a better understanding of the biology and pathogenicity of P. cinnamomi infection that can subsequently be used to develop effective methods of disease management....
Source: Journal of Proteomics - September 12, 2022 Category: Biochemistry Authors: Christina E Andronis Silke Jacques Richard Lipscombe Kar-Chun Tan Source Type: research

Response Surface Methodology Applied to the Optimization of the Preparation of Antioxidant and Antidiabetic Extracts from < em > Phragmanthera capitata < /em > (Spreng.) Balle: Effect of Particle Size, Powder-to-Solvent Ratio, and Temperature
Evid Based Complement Alternat Med. 2022 Sep 1;2022:8397250. doi: 10.1155/2022/8397250. eCollection 2022.ABSTRACTPhragmanthera capitata is a medicinal plant used in traditional medicine to treat several diseases, including diabetes. Its antioxidant properties and inhibitory effects on enzyme-carbohydrate digestion activities have been demonstrated. The present study aimed to provide data that can contribute to rationalizing the preparation of antioxidant and antidiabetic extracts from this plant. P. capitata (whole plant) growing on Persea americana was harvested at the fruiting stage. A response surface design-type centra...
Source: Evidence-based Complementary and Alternative Medicine - September 12, 2022 Category: Complementary Medicine Authors: C ésaire Feudjio Guy Sedar Singor Njateng Mathilde Julie Klang Muhammad Arfat Yameen Muhammad Ahsan Khan Jules-Roger Kuiate Source Type: research

Avocados, bananas, and pancakes: Does the oocyte maturity ratio predict live birth rates in in  vitro fertilization/intracytoplasmic sperm injection?
When I try to explain oocyte maturity to patients in the daily practice of assisted reproductive technology, I often talk about avocados and bananas. Most people can relate to the joy of eating a perfectly ripe banana or avocado and the dissatisfaction of biting into a green banana, a hard avocado, or a mushy version of either. Striving for the perfect ripeness of these fruits [yes, avocado is a fruit (1)] is similar to the quest to harvest oocytes at their “ripest,” most mature point in in vitro fertilization (IVF). (Source: Fertility and Sterility)
Source: Fertility and Sterility - September 4, 2022 Category: Reproduction Medicine Authors: Alexander M. Quaas Tags: Reflections Source Type: research

Baking from the stockroom and an artistic avocado substitute
(Source: Chemical and Engineering News)
Source: Chemical and Engineering News - September 1, 2022 Category: Chemistry Authors: Alex Scott Source Type: research

Avocado consumption is associated with a reduction in hypertension incidence in Mexican women
Br J Nutr. 2022 Aug 18:1-24. doi: 10.1017/S0007114522002690. Online ahead of print.ABSTRACTAvocado is a fruit rich in dietary fiber, potassium, magnesium, mono and polyunsaturated fatty acids, and bioactive phytochemicals, which are nutritional components that have been associated with cardiovascular health. Yet, despite the boom in avocado consumption, we lack evidence on its association with cardiovascular disease risk in the general population. To estimate the prospective association between avocado consumption and incident hypertension in Mexican women. We estimated the association in participants from the Mexican Teac...
Source: The British Journal of Nutrition - August 18, 2022 Category: Nutrition Authors: Adriana Monge Dalia Stern Adrian Cort és-Valencia Andr és Catzín-Kuhlmann Mart ín Lajous Edgar Denova-Guti érrez Source Type: research

Avocado consumption is associated with a reduction in hypertension incidence in Mexican women
Br J Nutr. 2022 Aug 18:1-24. doi: 10.1017/S0007114522002690. Online ahead of print.ABSTRACTAvocado is a fruit rich in dietary fiber, potassium, magnesium, mono and polyunsaturated fatty acids, and bioactive phytochemicals, which are nutritional components that have been associated with cardiovascular health. Yet, despite the boom in avocado consumption, we lack evidence on its association with cardiovascular disease risk in the general population. To estimate the prospective association between avocado consumption and incident hypertension in Mexican women. We estimated the association in participants from the Mexican Teac...
Source: The British Journal of Nutrition - August 18, 2022 Category: Nutrition Authors: Adriana Monge Dalia Stern Adrian Cort és-Valencia Andr és Catzín-Kuhlmann Mart ín Lajous Edgar Denova-Guti érrez Source Type: research