Characterization of emulgels formulated with phycocyanin and diutan gum as a novel approach for biocompatible delivery systems
Int J Biol Macromol. 2024 Apr 14:131599. doi: 10.1016/j.ijbiomac.2024.131599. Online ahead of print.ABSTRACTPhycocyanin (PC), a protein derived from algae, is non-toxic and biocompatible. Due to its environmental and sustainable properties, it has been studied as an alternative stabilizer for food emulsions. In this sense, the main objective of this work is to evaluate the effectiveness of PC and its use in combination with diutan gum (DG), a biological macromolecule, to prepare emulgels formulated with avocado oil. Z-potential measurements show that the optimum pH for working with PC is 2.5. Furthermore, the system exhibi...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Patricia Tello Jenifer Santos V íctor M Perez-Puyana Alberto Romero Luis A Trujillo-Cayado Source Type: research
Characterization of emulgels formulated with phycocyanin and diutan gum as a novel approach for biocompatible delivery systems
Int J Biol Macromol. 2024 Apr 14:131599. doi: 10.1016/j.ijbiomac.2024.131599. Online ahead of print.ABSTRACTPhycocyanin (PC), a protein derived from algae, is non-toxic and biocompatible. Due to its environmental and sustainable properties, it has been studied as an alternative stabilizer for food emulsions. In this sense, the main objective of this work is to evaluate the effectiveness of PC and its use in combination with diutan gum (DG), a biological macromolecule, to prepare emulgels formulated with avocado oil. Z-potential measurements show that the optimum pH for working with PC is 2.5. Furthermore, the system exhibi...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Patricia Tello Jenifer Santos V íctor M Perez-Puyana Alberto Romero Luis A Trujillo-Cayado Source Type: research
Rice starch modification by thermal treatments with avocado oil: Autoclave versus microwave methods
This study aimed to evaluate the physical and chemical alterations in rice starch modified by heat-moisture treatment (HMT) using an autoclave and a microwave, in association with avocado oil (AO), and evaluate the effects on thermal and structural properties, in vitro digestibility, and estimated glycemic index (eGI). Samples were adjusted to 30 % (w/w) moisture and 2, 4 and 8 % AO. HMT was conducted at 110 °C for 1 h in the autoclave (A0%, A2%, A4%, and A8%) and at 50 °C for 3 min in the microwave (M0%, M2%, M4%, and M8%). Both procedures did not alter the starch crystallinity pattern (type-A). Pasting viscosity, setba...
Source: International Journal of Biological Macromolecules - April 7, 2024 Category: Biochemistry Authors: Sabrina Feksa Frasson Rosana Colussi Helen Cristina Dos Santos Hackbart Caroline Dellinghausen Borges Wladimir Hernandez Flores Carla Rosane Barboza Mendon ça Source Type: research
Rice starch modification by thermal treatments with avocado oil: Autoclave versus microwave methods
This study aimed to evaluate the physical and chemical alterations in rice starch modified by heat-moisture treatment (HMT) using an autoclave and a microwave, in association with avocado oil (AO), and evaluate the effects on thermal and structural properties, in vitro digestibility, and estimated glycemic index (eGI). Samples were adjusted to 30 % (w/w) moisture and 2, 4 and 8 % AO. HMT was conducted at 110 °C for 1 h in the autoclave (A0%, A2%, A4%, and A8%) and at 50 °C for 3 min in the microwave (M0%, M2%, M4%, and M8%). Both procedures did not alter the starch crystallinity pattern (type-A). Pasting viscosity, setba...
Source: International Journal of Biological Macromolecules - April 7, 2024 Category: Biochemistry Authors: Sabrina Feksa Frasson Rosana Colussi Helen Cristina Dos Santos Hackbart Caroline Dellinghausen Borges Wladimir Hernandez Flores Carla Rosane Barboza Mendon ça Source Type: research
Advancing abiotic stress monitoring in plants with a wearable non-destructive real-time salicylic acid laser-induced-graphene sensor
Biosens Bioelectron. 2024 Mar 31;255:116261. doi: 10.1016/j.bios.2024.116261. Online ahead of print.ABSTRACTDrought and salinity stresses present significant challenges that exert a severe impact on crop productivity worldwide. Understanding the dynamics of salicylic acid (SA), a vital phytohormone involved in stress response, can provide valuable insights into the mechanisms of plant adaptation to cope with these challenging conditions. This paper describes and tests a sensor system that enables real-time and non-invasive monitoring of SA content in avocado plants exposed to drought and salinity. By using a reverse iontop...
Source: Biosensors and Bioelectronics - April 2, 2024 Category: Biotechnology Authors: Sammy A Perdomo Drochss Pettry Valencia Gabriel Esteban Velez Andres Jaramillo-Botero Source Type: research
Advancing abiotic stress monitoring in plants with a wearable non-destructive real-time salicylic acid laser-induced-graphene sensor
Biosens Bioelectron. 2024 Mar 31;255:116261. doi: 10.1016/j.bios.2024.116261. Online ahead of print.ABSTRACTDrought and salinity stresses present significant challenges that exert a severe impact on crop productivity worldwide. Understanding the dynamics of salicylic acid (SA), a vital phytohormone involved in stress response, can provide valuable insights into the mechanisms of plant adaptation to cope with these challenging conditions. This paper describes and tests a sensor system that enables real-time and non-invasive monitoring of SA content in avocado plants exposed to drought and salinity. By using a reverse iontop...
Source: Biosensors and Bioelectronics - April 2, 2024 Category: Biotechnology Authors: Sammy A Perdomo Drochss Pettry Valencia Gabriel Esteban Velez Andres Jaramillo-Botero Source Type: research
Suppression of Inflammation in Ulcerative Colitis Rats by Avocado and Pomegranate
Pomegranate seed oil (PSO) and avocado seed oil (ASO) are natural polyphenols with established anti-inflammatory activity. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - April 2, 2024 Category: Nutrition Authors: Nahla E. El-Ashmawy, Eman G. Khedr, Enas A. El-Zamarany, Sarah M. Ahmed Tags: Original article Source Type: research
Co-Processed Crystalline Solids of Ivermectin with Span < sup > ® < /sup > 60 as Solubility Enhancers of Ivermectin in Natural Oils
In this study, polymorphic and co-crystal screening was used to see if such solid-state modifications can improve the oil solubility of ivermectin. Span® 60, a lipophilic non-ionic surfactant, was chosen as co-former. The rationale behind attempting to improve oil solubility was to use ivermectin in future topical and transdermal preparations to treat a range of skin conditions like scabies and head lice. Physical mixtures were also prepared in the same molar ratios as the co-crystal candidates, to serve as controls. Solid-state characterization was performed using X-ray powder diffraction (XRPD), Fourier-transform infrar...
Source: AAPS PharmSciTech - March 23, 2024 Category: Drugs & Pharmacology Authors: Luandri de Vos Minja Gerber Wilna Liebenberg Johanna C Wessels Hendrik J R Lemmer Source Type: research
Co-Processed Crystalline Solids of Ivermectin with Span < sup > ® < /sup > 60 as Solubility Enhancers of Ivermectin in Natural Oils
In this study, polymorphic and co-crystal screening was used to see if such solid-state modifications can improve the oil solubility of ivermectin. Span® 60, a lipophilic non-ionic surfactant, was chosen as co-former. The rationale behind attempting to improve oil solubility was to use ivermectin in future topical and transdermal preparations to treat a range of skin conditions like scabies and head lice. Physical mixtures were also prepared in the same molar ratios as the co-crystal candidates, to serve as controls. Solid-state characterization was performed using X-ray powder diffraction (XRPD), Fourier-transform infrar...
Source: AAPS PharmSciTech - March 23, 2024 Category: Drugs & Pharmacology Authors: Luandri de Vos Minja Gerber Wilna Liebenberg Johanna C Wessels Hendrik J R Lemmer Source Type: research
Co-Processed Crystalline Solids of Ivermectin with Span < sup > ® < /sup > 60 as Solubility Enhancers of Ivermectin in Natural Oils
In this study, polymorphic and co-crystal screening was used to see if such solid-state modifications can improve the oil solubility of ivermectin. Span® 60, a lipophilic non-ionic surfactant, was chosen as co-former. The rationale behind attempting to improve oil solubility was to use ivermectin in future topical and transdermal preparations to treat a range of skin conditions like scabies and head lice. Physical mixtures were also prepared in the same molar ratios as the co-crystal candidates, to serve as controls. Solid-state characterization was performed using X-ray powder diffraction (XRPD), Fourier-transform infrar...
Source: AAPS PharmSciTech - March 23, 2024 Category: Drugs & Pharmacology Authors: Luandri de Vos Minja Gerber Wilna Liebenberg Johanna C Wessels Hendrik J R Lemmer Source Type: research
Co-Processed Crystalline Solids of Ivermectin with Span < sup > ® < /sup > 60 as Solubility Enhancers of Ivermectin in Natural Oils
In this study, polymorphic and co-crystal screening was used to see if such solid-state modifications can improve the oil solubility of ivermectin. Span® 60, a lipophilic non-ionic surfactant, was chosen as co-former. The rationale behind attempting to improve oil solubility was to use ivermectin in future topical and transdermal preparations to treat a range of skin conditions like scabies and head lice. Physical mixtures were also prepared in the same molar ratios as the co-crystal candidates, to serve as controls. Solid-state characterization was performed using X-ray powder diffraction (XRPD), Fourier-transform infrar...
Source: AAPS PharmSciTech - March 23, 2024 Category: Drugs & Pharmacology Authors: Luandri de Vos Minja Gerber Wilna Liebenberg Johanna C Wessels Hendrik J R Lemmer Source Type: research
Avocado seed starch utilized in eco-friendly, UV-blocking, and high-barrier polylactic acid (PLA) biocomposites for active food packaging applications
This study can show the great potential of extracting starch from biowaste resources and transforming it into sustainable bio-based composites as a promising solution for food packaging applications.PMID:38503372 | DOI:10.1016/j.ijbiomac.2024.130837 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - March 19, 2024 Category: Biochemistry Authors: Marcela Mar ía Godoy Zúniga Ruonan Ding Eunyoung Oh Tan Binh Nguyen Tien Tran Trung Jae-Do Nam Jonghwan Suhr Source Type: research
Avocado-derived extracellular vesicles loaded with ginkgetin and berberine prevent inflammation and macrophage foam cell formation
J Cell Mol Med. 2024 Apr;28(7):e18177. doi: 10.1111/jcmm.18177.ABSTRACTAtherosclerosis, a chronic inflammatory disease of aorta, remains the major cause of morbidity and mortality among cardiovascular disease patients. Macrophage foam cell formation and inflammation are critically involved in early stages of atherosclerosis, hence chemopreventive targeting of foam cell formation by nutraceuticals may be a promising approach to curbing the progression of atherosclerosis. However, many nutraceuticals including berberine and ginkgetin have low stability, tissue/cell penetration and bioavailability resulting in inadequate chem...
Source: J Cell Mol Med - March 18, 2024 Category: Molecular Biology Authors: Shweta Sharma Manisha Mahanty Suneha G Rahaman Pritha Mukherjee Bidisha Dutta Mohammad Imran Khan Karunakaran Reddy Sankaran Xiaoming He Lakshmyya Kesavalu Wei Li Shaik O Rahaman Source Type: research
Avocado-derived extracellular vesicles loaded with ginkgetin and berberine prevent inflammation and macrophage foam cell formation
J Cell Mol Med. 2024 Apr;28(7):e18177. doi: 10.1111/jcmm.18177.ABSTRACTAtherosclerosis, a chronic inflammatory disease of aorta, remains the major cause of morbidity and mortality among cardiovascular disease patients. Macrophage foam cell formation and inflammation are critically involved in early stages of atherosclerosis, hence chemopreventive targeting of foam cell formation by nutraceuticals may be a promising approach to curbing the progression of atherosclerosis. However, many nutraceuticals including berberine and ginkgetin have low stability, tissue/cell penetration and bioavailability resulting in inadequate chem...
Source: J Cell Mol Med - March 18, 2024 Category: Molecular Biology Authors: Shweta Sharma Manisha Mahanty Suneha G Rahaman Pritha Mukherjee Bidisha Dutta Mohammad Imran Khan Karunakaran Reddy Sankaran Xiaoming He Lakshmyya Kesavalu Wei Li Shaik O Rahaman Source Type: research
Avocado-derived extracellular vesicles loaded with ginkgetin and berberine prevent inflammation and macrophage foam cell formation
J Cell Mol Med. 2024 Apr;28(7):e18177. doi: 10.1111/jcmm.18177.ABSTRACTAtherosclerosis, a chronic inflammatory disease of aorta, remains the major cause of morbidity and mortality among cardiovascular disease patients. Macrophage foam cell formation and inflammation are critically involved in early stages of atherosclerosis, hence chemopreventive targeting of foam cell formation by nutraceuticals may be a promising approach to curbing the progression of atherosclerosis. However, many nutraceuticals including berberine and ginkgetin have low stability, tissue/cell penetration and bioavailability resulting in inadequate chem...
Source: Molecular Medicine - March 18, 2024 Category: Molecular Biology Authors: Shweta Sharma Manisha Mahanty Suneha G Rahaman Pritha Mukherjee Bidisha Dutta Mohammad Imran Khan Karunakaran Reddy Sankaran Xiaoming He Lakshmyya Kesavalu Wei Li Shaik O Rahaman Source Type: research
