Efficacy of catheter ablation for atrial fibrillation in heart failure: a meta ‐analysis of randomized controlled trials
AbstractThe study aims to evaluate whether rhythm control by catheter ablation is superior to medical therapy for the patients with atrial fibrillation (AF) and heart failure (HF). The literatures were searched by using PubMed, Cochrane Library, Embase, and Web of Science databases up to 12 October 2023. The randomized controlled trials (RCTs) comparing rhythm control using catheter ablation vs. medical therapy in AF patients with HF were pooled. The primary outcomes included all-cause mortality, HF re-hospitalization, and stroke, and the secondary outcomes included left ventricular ejection fraction (LVEF), atrial tachyar...
Source: ESC Heart Failure - April 26, 2024 Category: Cardiology Authors: Zhongyin Zhang,
Yan Zheng,
Wenxiu He,
Jiahe Wei,
Pengzhan Li,
Guoqiang Zhong,
Zhiyuan Jiang Tags: Review Source Type: research
Adjunctive low ‐voltage area ablation for patients with atrial fibrillation: An updated meta‐analysis of randomized controlled trials
ConclusionsAdjunctive LVA ablation is an effective and safe strategy for reducing recurrences of ATA among patients who undergo CA for AF. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - April 26, 2024 Category: Cardiology Authors: Andr é Rivera,
Douglas M. Gewehr,
Marcelo A. P. Braga,
Pedro E. P. Carvalho,
Caique M. P. Ternes,
Alexandre N. Pantaleao,
Daniela Hincapie,
Frans Serpa,
Jorge E. Romero,
André d'Avila Tags: ORIGINAL ARTICLE Source Type: research
Trends in percutaneous left atrial appendage occlusion and 1-year mortality 2013 –2021: A nationwide observational study
Percutaneous left atrial appendage occlusion (LAAO) is increasingly used for stroke prevention in patients with atrial fibrillation and anticoagulant-related complications. Yet, real-life studies evaluating changes in patient characteristics and indications for LAAO remain scarce. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 26, 2024 Category: Cardiology Authors: Olivia J. Madsen, Morten Lamberts, Jonas B. Olesen, Morten L. Hansen, Thomas K ümler, Erik L. Grove, Niels H. Andersen, Emil Fosbøl, Ole De Backer, Jarl E. Strange Source Type: research
Cancer and arterial thrombosis: therapeutic options
Res Pract Thromb Haemost. 2024 Mar 27;8(3):102393. doi: 10.1016/j.rpth.2024.102393. eCollection 2024 Mar.ABSTRACTA State of the Art lecture titled "Cancer and Arterial Thrombosis: Therapeutic Options" was presented at the International Society on Thrombosis and Haemostasis Congress in 2023. This State of the Art review delves into the complex relationship between cancer and arterial thromboembolism (ATE), encompassing acute coronary syndrome, ischemic strokes, and peripheral arterial disease. The burden of cancer-associated ATE is not well defined, but studies indicate elevated risks, particularly in the 6 months after a c...
Source: Thrombosis and Haemostasis - April 25, 2024 Category: Hematology Authors: May Anne Cheong Avi Leader Source Type: research
A young patient with Graves' disease presenting with a triad of heart failure, pancytopenia, and jaundice: A case report
We describe a case of a young man who presented with progressive cough, increased abdominal girth and ankle swelling for a few months. On examination, he had jaundice, bilateral exophthalmos, diffuse goiter, ascites, and significant lower limb edema. Laboratory investigations showed increased Thyroxin level with a suppressed thyroid stimulating hormone and positive anti-thyrotropin receptor antibodies. Also, the patient had pancytopenia, coagulopathy and cholestatic pattern of elevated liver enzymes. Echocardiography demonstrated mildly reduced left ventricular function with diastolic dysfunction, but electrocardiogram did...
Source: Clinical Case Reports - April 25, 2024 Category: General Medicine Authors: Mohamed Kamal Sabra,
Anwar Joudeh,
Mahmoud Al Niserat,
Riyadh Hammamy Tags: CASE REPORT Source Type: research
Birth cohort effect in atrial fibrillation: a matter of detection?
Atrial fibrillation (AF) is the most common sustained cardiac rhythm disorder, affecting an estimated 43 million people globally.1 In the last 20 years, the incidence of AF increased by 33% and it is expected to increase by threefold in the next three decades.1 Long-term AF management, including outpatient visits, hospitalisations and disabilities from stroke and heart failure (HF), adds substantial burden on healthcare resources and costs, accounting for 2.6% of the total annual healthcare expenditure of European countries.2 As a result, AF has emerged as a major public health concern and a potential future epidemic.1 The...
Source: Heart - April 25, 2024 Category: Cardiology Authors: Samuel, M., Rienstra, M. Tags: Editorials Source Type: research
Birth cohort effects on diagnosed atrial fibrillation incidence: nationwide cohort study from 1980 to 2018
Conclusion
Substantial birth cohort effects, independent of age and calendar period, influence trends in diagnosed AF incidence. (Source: Heart)
Source: Heart - April 25, 2024 Category: Cardiology Authors: Vinter, N., Cordsen, P., Johnsen, S. P., Benjamin, E. J., Frost, L., Trinquart, L. Tags: Arrhythmias and sudden death Source Type: research
Predictors of outcome in patients with moderate mixed aortic valve disease
Conclusions
Patients with truly moderate MAVD have a high incidence of death and heart failure hospitalisation (43% at 3.5 (2.5–4.7) years). Within this group, a high-risk group characterised by disproportionately low aortic Vmax (≤2.8 m/s) and adverse remodelling (LVEF ≤50%) have the worst outcomes. (Source: Heart)
Source: Heart - April 25, 2024 Category: Cardiology Authors: Patel, K. P., McKenna, M., Thornton, G. D., Vandermolen, S., Abdulelah, Z. A., Awad, W., Baumbach, A., Mathur, A., Treibel, T. A., Lloyd, G., Mullen, M. J., Bhattacharyya, S. Tags: Valvular heart disease Source Type: research
Novel electrocardiographic classification for stroke prediction in atrial fibrillation patients undergoing cardioversion
Abnormal conduction, structure and function of the atrial myocardium predispose to atrial fibrillation (AF) and stroke. Usefulness of electrocardiographic (ECG) indices in predicting stroke or systemic embolism (SSE) in patients undergoing cardioversion for AF remains unknown, especially in those at low estimated risk. (Source: Heart Rhythm)
Source: Heart Rhythm - April 25, 2024 Category: Cardiology Authors: Arto Relander, Ilkka Ruohonen, Samuli Jaakkola, Tuija Vasankari, Ilpo Nuotio, Juhani Airaksinen, Tuomas Kiviniemi Source Type: research
Periodontal treatment reduces AF recurrence
Nature Reviews Cardiology, Published online: 25 April 2024; doi:10.1038/s41569-024-01036-8Treatment for periodontal disease might reduce the recurrence of atrial fibrillation (AF) in patients undergoing ablation, suggesting that periodontitis is a modifiable risk factor for AF. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - April 25, 2024 Category: Cardiology Authors: Gregory B. Lim Source Type: research
The foundation for investigating factor XI as a target for inhibition in human cardiovascular disease
AbstractAnticoagulant therapy is a mainstay in the management of patients with cardiovascular disease and related conditions characterized by a heightened risk for thrombosis. Acute coronary syndrome, chronic coronary syndrome, ischemic stroke, and atrial fibrillation are the most common. In addition to their proclivity for thrombosis, each of these four conditions is also characterized by local and systemic inflammation, endothelial/endocardial injury and dysfunction, oxidative stress, impaired tissue-level reparative capabilities, and immune dysregulation that plays a critical role in linking molecular events, environmen...
Source: Journal of Thrombosis and Thrombolysis - April 25, 2024 Category: Hematology Source Type: research
Randomised controlled trial of population screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the SAFER trial
Introduction
There is a lack of evidence that the benefits of screening for atrial fibrillation (AF) outweigh the harms. Following the completion of the Screening for Atrial Fibrillation with ECG to Reduce stroke (SAFER) pilot trial, the aim of the main SAFER trial is to establish whether population screening for AF reduces incidence of stroke risk.
Methods and analysis
Approximately 82 000 people aged 70 years and over and not on oral anticoagulation are being recruited from general practices in England. Patients on the palliative care register or residents in a nursing home are excluded. Eligible people are identified u...
Source: BMJ Open - April 25, 2024 Category: General Medicine Authors: Mant, J., Modi, R. N., Dymond, A., Armstrong, N., Burt, J., Calvert, P., Cowie, M., Ding, W. Y., Edwards, D., Freedman, B., Griffin, S. J., Hoare, S., Hobbs, F. D. R., Johnson, R., Kaptoge, S., Lip, G. Y. H., Lobban, T., Lown, M., Lund, J., McManus, R. J. Tags: Open access, Cardiovascular medicine Source Type: research
Identification of common mechanisms and biomarkers of atrial fibrillation and heart failure based on machine learning
ConclusionsWe identified four biological markers that are highly correlated with AF and HF, namely,GLUL,NCF2,S100A12, andSRGN. Our findings provide theoretical basis for the clinical diagnosis and treatment of AF and HF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 24, 2024 Category: Cardiology Authors: Zhijun Zhang,
Jianying Ding,
Xiaolong Mi,
Yuanyuan Lin,
Xinjian Li,
Jun Lian,
Jinwen Liu,
Lijuan Qu,
Bingye Zhao,
Xuewen Li Tags: Original Article Source Type: research
Preserving the Right Ventricular Function: Early Rhythm Control Through Ablation of Persistent Atrial Fibrillation
Korean Circ J. 2024 Apr;54(4):218-220. doi: 10.4070/kcj.2024.0102.NO ABSTRACTPMID:38654568 | DOI:10.4070/kcj.2024.0102 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Min-Su Jung Hyoung-Seob Park Source Type: research
The Effects of Radiofrequency Catheter Ablation for Atrial Fibrillation on Right Ventricular Function
CONCLUSIONS: RV systolic function is more impaired in patients with PeAF and LSPeAF than in those with PAF. RV systolic function is more improved after RFCA in patients with PeAF than in those with PAF or LSPeAF.PMID:38654567 | DOI:10.4070/kcj.2023.0312 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - April 24, 2024 Category: Cardiology Authors: Minkwan Kim Jae-Sun Uhm Je-Wook Park SungA Bae In Hyun Jung Seok-Jae Heo Daehoon Kim Hee Tae Yu Tae-Hoon Kim Boyoung Joung Moon-Hyoung Lee Source Type: research
