Lb-469809-03 short- and long-term clinical outcomes of radiofrequency catheter ablation in paroxysmal atrial fibrillation: results from the prospective multicenter real-af registry
The impact of contemporary techniques and technologies to optimize ablation delivery, reduce fluoroscopy use, and improve clinical outcomes using radiofrequency catheter ablation (RF-CA) for paroxysmal atrial fibrillation (PAF) has not been assessed in systematic, large, prospective, multicenter registries. We aimed to assess the contemporary real-world practice approach, procedural and long-term clinical outcomes of RF-CA for PAF through a large prospective multicenter registry. (Source: Heart Rhythm)
Source: Heart Rhythm - May 2, 2024 Category: Cardiology Authors: Paul C. Zei, Jose Osorio, Andr és F. Miranda-Arboleda, Joshua R. Silverstein, Saumil R. Oza, Anthony R. Magnano, Jorge Romero, Carlos D. Matos, Carolina Hoyos, Fernando Moreno, Daniela Hincapie Tabares, Anil Rajendra, Gustavo X. Morales, Alexandru I. Cos Source Type: research
Lb-469809-01 mediterranean diet enriched with extra-virgin olive oil reduced risk of tachyarrhythmia recurrence after atrial fibrillation ablation: the predimar trial
AF ablation has limited success. The PREDIMED trial showed that a Mediterranean diet(MeDiet) enriched with extra-virgin olive oil (EVOO) reduces incidental AF. The PREDIMAR trial assessed the effect of this dietary pattern on arrhythmia recurrence after ablation. (Source: Heart Rhythm)
Source: Heart Rhythm - May 2, 2024 Category: Cardiology Authors: Maria T. Barrio-Lopez, Miguel Angel Martinez Gonzalez, Jesus Almendral, Pablo Ramos Ardanaz, Luis Tercedor, Jose L. Iba ñez Criado, Leticia Goni, Victor de la O, Ignacio Garcia-Bolao, Rosa Macias, Alicia Ibañez Criado, Miguel Ruiz-Canela Source Type: research
Lb-469807-05 outcomes with and without oral anticoagulation in patients with prior stroke and device-detected atrial fibrillation: the noah-afnet 6 trial
Patients with a prior stroke are at high risk of recurrent strokes. In patients with ECG-documented atrial fibrillation (AF), anticoagulation reduces subsequent strokes. Detection of short and rare episodes of atrial fibrillation using implanted devices (device-detected AF, DDAF) is common in patients with a prior stroke and these patients are often treated with an anticoagulant when DDAF is detected. Data on the effectiveness and safety of oral anticoagulation in patients a prior stroke and DDAF but no ECG-documented AF are lacking. (Source: Heart Rhythm)
Source: Heart Rhythm - May 2, 2024 Category: Cardiology Authors: Hans Diener, Gregory Lip, Julius Nikorowitsch, Nina Becher, Carina Blomstr öm-Lundqvist, A. John Camm, Gregory Chlouverakis, Andreas Goette, Ulrich Schotten, Emmanuel Simantirakis, Tobias Toennis, Panos Vardas, Antonia Zapf, Susanne Sehner, Renate B. Sch Source Type: research
Lb-469807-04 efficacy and safety of apixaban versus aspirin according to cha2ds2-vasc score in patients with subclinical atrial fibrillation in artesia
ARTESiA showed that apixaban, compared to aspirin, significantly reduced stroke or systemic embolism (SE) but increased major bleeding in patients with subclinical atrial fibrillation (SCAF). To better inform benefit-to-risk decision-making for the use of apixaban, we evaluated the benefits and hazards of apixaban according to baseline CHA2DS2-VASc score. (Source: Heart Rhythm)
Source: Heart Rhythm - May 2, 2024 Category: Cardiology Authors: Jeffrey S. Healey, Christopher Granger, William F. McIntyre, Marco Alings, Daniel Wojdyla, Chinthanie Ramasundarahettige, Lena Rivard, Dan Atar, David H. Birnie, Giuseppe Boriani, Guy Amit, Peter Leong-Sit, Claus H. Rinne, Gabor Duray, Michael R. Gold, St Source Type: research
2023 Cardiac Society of Australia and New Zealand Expert Position Statement on Catheter and Surgical Ablation for Atrial Fibrillation
Catheter ablation for atrial fibrillation (AF) has increased exponentially in many developed countries, including Australia and New Zealand. This Expert Position Statement on Catheter and Surgical Ablation for Atrial Fibrillation from the Cardiac Society of Australia and New Zealand (CSANZ) recognises healthcare factors, expertise and expenditure relevant to the Australian and New Zealand healthcare environments including considerations of potential implications for First Nations Peoples. The statement is cognisant of international advice but tailored to local conditions and populations, and is intended to be used by elect...
Source: Heart, Lung and Circulation - May 2, 2024 Category: Cardiology Authors: Peter M. Kistler, Prash Sanders, John V. Amarena, Chris R. Bain, Karin M. Chia, Wai-Kah Choo, Adam T. Eslick, Tanya Hall, Ingrid K. Hopper, Emily Kotschet, Han S. Lim, Liang-Han Ling, Rajiv Mahajan, Silvana F. Marasco, Mark A. McGuire, Alex J. McLellan, R Tags: Position Statement Source Type: research
Apixaban Reduces Risk of Stroke or Systemic Embolism in Subclinical AF
Dr. Watson
Clinical question: Does oral anti-coagulation reduce stroke or systemic embolism risk in subclinical atrial fibrillation (AF)?
Background: Studies have shown an increased risk of stroke and systemic embolism in subclinical AF (short, asymptomatic episodes detected by permanent pacemakers and implantable cardiac defibrillators). While oral anti-coagulation has a well-recognized role in the treatment of clinical AF, its role in subclinical AF is uncertain.
Study design: Randomized controlled trial
Setting: 247 clinical sites in 16 European and North American countries
Synopsis: The study included 4,012 patients w...
Source: The Hospitalist - May 1, 2024 Category: Hospital Management Authors: Ronda Whitaker Tags: Cardiology In the Literature Source Type: research
High Frequency of AF Recurrence in Hospitalized Patients with New-onset AF
Dr. Watson
Clinical question: What is the frequency of atrial fibrillation (AF) recurrence in patients with new-onset AF, detected while hospitalized for a noncardiac medical illness or surgery, that returns to sinus rhythm prior to discharge?
Background: AF is frequently detected for the first time in patients hospitalized for a noncardiac medical illness or surgery and may be considered a provoked and transient phenomenon (rather than a paroxysmal one) in these instances. The frequency of AF recurrence and appropriate medical management in this population is unclear.
Study design: Matched cohort study
Setting: Three aca...
Source: The Hospitalist - May 1, 2024 Category: Hospital Management Authors: Ronda Whitaker Tags: Cardiology In the Literature Source Type: research
Elevated cardiovascular risk and acute events in hospitalized colon cancer survivors: A decade-apart study of two nationwide cohorts
CONCLUSION: Colon cancer survivors hospitalized 10 years apart in the United States showed an increased CVD risk with an increased risk of acute cardiovascular events (stroke 28%, PE 47%, arrhythmia 41%, and cardiac arrest 63%). It is vital to regularly screen colon cancer survivors with concomitant CVD risk factors to curtail long-term cardiovascular complications.PMID:38689632 | PMC:PMC11056864 | DOI:10.5306/wjco.v15.i4.548 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - May 1, 2024 Category: Cancer & Oncology Authors: Rupak Desai Avilash Mondal Vivek Patel Sandeep Singh Shaylika Chauhan Akhil Jain Source Type: research
Ertugliflozin for Functional Mitral Regurgitation Associated With Heart Failure: EFFORT Trial
CONCLUSIONS: Among patients with functional MR associated with HF, ertugliflozin significantly improved LV global longitudinal strain and left atrial remodeling, and reduced functional MR. Sodium-glucose cotransporter 2 inhibitors may be considered for patients with functional MR.REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT04231331.PMID:38690659 | DOI:10.1161/CIRCULATIONAHA.124.069144 (Source: Circulation)
Source: Circulation - May 1, 2024 Category: Cardiology Authors: Duk-Hyun Kang Sung-Ji Park Sung-Hee Shin In-Chang Hwang Yeonyee Elizabeth Yoon Hyung-Kwan Kim Mijin Kim Min-Seok Kim Sung-Cheol Yun Jong-Min Song Seok-Min Kang Source Type: research
Ziprasidone triggers inflammasome signaling via PI3K-Akt-mTOR pathway to promote atrial fibrillation
CONCLUSIONS: Our findings suggest ziprasidone induces atrial arrhythmia, potentially through upregulation of the NLRP3 inflammasome and enhancement of reactive oxygen species production via the PI3K/Akt/mTOR pathway.PMID:38692059 | DOI:10.1016/j.biopha.2024.116649 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 1, 2024 Category: Drugs & Pharmacology Authors: Ming-Kun Lu Yen-Nien Huo Buh-Yuan Tai Chih-Yuan Lin Hsiang-Yu Yang Chien-Sung Tsai Source Type: research
Elevated cardiovascular risk and acute events in hospitalized colon cancer survivors: A decade-apart study of two nationwide cohorts
CONCLUSION: Colon cancer survivors hospitalized 10 years apart in the United States showed an increased CVD risk with an increased risk of acute cardiovascular events (stroke 28%, PE 47%, arrhythmia 41%, and cardiac arrest 63%). It is vital to regularly screen colon cancer survivors with concomitant CVD risk factors to curtail long-term cardiovascular complications.PMID:38689632 | PMC:PMC11056864 | DOI:10.5306/wjco.v15.i4.548 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - May 1, 2024 Category: Cancer & Oncology Authors: Rupak Desai Avilash Mondal Vivek Patel Sandeep Singh Shaylika Chauhan Akhil Jain Source Type: research
Ziprasidone triggers inflammasome signaling via PI3K-Akt-mTOR pathway to promote atrial fibrillation
CONCLUSIONS: Our findings suggest ziprasidone induces atrial arrhythmia, potentially through upregulation of the NLRP3 inflammasome and enhancement of reactive oxygen species production via the PI3K/Akt/mTOR pathway.PMID:38692059 | DOI:10.1016/j.biopha.2024.116649 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 1, 2024 Category: Drugs & Pharmacology Authors: Ming-Kun Lu Yen-Nien Huo Buh-Yuan Tai Chih-Yuan Lin Hsiang-Yu Yang Chien-Sung Tsai Source Type: research
Chinese guidelines for the diagnosis and management of atrial fibrillation
AbstractAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia, significantly impacting patients' quality of life and increasing the risk of death, stroke, heart failure, and dementia. Over the past two decades, there have been significant breakthroughs in AF risk prediction and screening, stroke prevention, rhythm control, catheter ablation, and integrated management. During this period, the scale, quality, and experience of AF management in China have greatly improved, providing a solid foundation for the development of the guidelines for the diagnosis and management of AF. To further promote standardiz...
Source: Pacing and Clinical Electrophysiology : PACE - May 1, 2024 Category: Cardiology Authors: Changsheng Ma,
Shulin Wu,
Shaowen Liu,
Yaling Han Tags: ELECTROPHYSIOLOGY Source Type: research
Rheumatic heart disease of the mitral valve alongside the papillary fibroelastoma of the aortic valve: A case report
We present the case of a 47-year-old woman who was admitted to the hospital due to worsening dyspnea and fatigue, during which time she discovered an aortic valve papillary fibroelastoma. Further investigations revealed two thrombi in her left atrium and left atrial appendage, along with significant rheumatic mitral valve stenosis. The patient underwent thrombectomy, mitral valve replacement, and valve-sparing aortic valve tumor resection. Following surgery, the patient's recovery was unremarkable. This case report emphasizes the need for a comprehensive evaluation in patients with rheumatic mitral stenosis, considering al...
Source: Clinical Case Reports - May 1, 2024 Category: General Medicine Authors: Naser Khezerlouy Aghdam,
Mitra Delkhah,
Saeid Danayi,
Navid Sobhi Tags: CASE REPORT Source Type: research
Treating Atrial Fibrillation Is No MAZE: A Reminder To Heart Teams For Concomitant Surgical Ablation For Atrial Fibrillation With Cardiac Surgery
Atrial fibrillation (AF) is the most prevalent arrythmia and is often found during time of other cardiac pathologies which require surgical management including coronary revascularization and valve surgery. Surgical ablation of AF, most frequently performed via the Cox-Maze IV procedure, is highly effective in restoring sinus rhythm. Despite robust society guideline recommendations for concomitant surgical ablation (CSA) for AF, the practice has yet to be widely adopted. In this review, we discuss the current indications for CSA, its efficacy in maintaining freedom from atrial tachyarrhythmias, stroke, and adverse long-ter...
Source: The American Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Raghav Chandra, Jason Guo, Jewon Sohn, Michael E. Jessen, Christopher A. Heid Source Type: research
