Accelerator-based neutron sources for BNCT
ConclusionsThe use of exothermal deuteron-induced Be(d,n) and13C(d,n) reactions allows us to use the smallest energy machine, at 1.45  MeV, for AB-BNCT. It is shown that among the systems proposed the13C(d,n) solution is the one with the lowest overall activation (target  + BSA). Coupled to an AlF3 BSA (which undergoes no long term activation), a 30 mA deuteron beam on a13C target can deliver a good quality BNCT treatment for a deep seated brain tumor in one hour. (Source: Health and Technology)
Source: Health and Technology - March 18, 2024 Category: Information Technology Source Type: research

Integrated biomarker responses in wild populations of the intertidal sea anemone Bunodosoma zamponii living under different anthropogenic pressures
Environ Sci Pollut Res Int. 2024 Mar 16. doi: 10.1007/s11356-024-32926-6. Online ahead of print.ABSTRACTBunodosoma zamponii is the most abundant anemone in Mar del Plata (Buenos Aires, Argentina). Given that the presence of persistent organic pollutants (organochlorine pesticides and PCBs) and the organophosphate pesticide chlorpyrifos has recently been reported in this species, two wild populations living under different anthropogenic pressures were studied and compared regarding basic aspects of their ecology and physiological response to oxidative stress. A population from an impacted site (Las Delicias, LD) and another...
Source: Environmental Science and Pollution Research International - March 16, 2024 Category: Environmental Health Authors: Nicolas D Vazquez Andrea C Crupkin Melisa A Chierichetti Fabi án H Acuña Karina S B Miglioranza Source Type: research

Integrated biomarker responses in wild populations of the intertidal sea anemone Bunodosoma zamponii living under different anthropogenic pressures
Environ Sci Pollut Res Int. 2024 Mar 16. doi: 10.1007/s11356-024-32926-6. Online ahead of print.ABSTRACTBunodosoma zamponii is the most abundant anemone in Mar del Plata (Buenos Aires, Argentina). Given that the presence of persistent organic pollutants (organochlorine pesticides and PCBs) and the organophosphate pesticide chlorpyrifos has recently been reported in this species, two wild populations living under different anthropogenic pressures were studied and compared regarding basic aspects of their ecology and physiological response to oxidative stress. A population from an impacted site (Las Delicias, LD) and another...
Source: Environmental Science and Pollution Research International - March 16, 2024 Category: Environmental Health Authors: Nicolas D Vazquez Andrea C Crupkin Melisa A Chierichetti Fabi án H Acuña Karina S B Miglioranza Source Type: research

Comparative evaluation of four rapid diagnostic tests that detect human < i > Trypanosoma cruzi- < /i > specific antibodies to support diagnosis of Chagas Disease in urban population of Argentina
ConclusionsOur study demonstrates that, under controlled laboratory conditions, commercially available RDTs for CD have a performance comparable to the Argentinian diagnostic algorithm, which is based on laboratory-based serological tests. For the next stage of our work, the RDTs will be evaluated in real-world settings. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - March 15, 2024 Category: Tropical Medicine Authors: Roc ío Rivero Source Type: research

Validating the implementation of an indicator reporting policies and laws on free public maternal health-related services in the era of universal health coverage: A multi-country cross-sectional study
ConclusionsFree care laws were largely accurately reported in the global MNCAH policy database. Notably, we found that women absorbed both direct and indirect costs and made both formal and informal payments for services designated as free. Therefore, the policy indicator does not provide a valid reflection of UHC in the three settings. (Source: PLoS One)
Source: PLoS One - March 13, 2024 Category: Biomedical Science Authors: Magdalene A. Odikro Source Type: research

Inhibitory action of antibiotics on Kluyveromyces marxianus
Rev Argent Microbiol. 2024 Mar 11:S0325-7541(24)00006-3. doi: 10.1016/j.ram.2023.12.004. Online ahead of print.ABSTRACTA bioassay containing Kluyveromyces marxianus in microtiter plates was used to determine the inhibitory action of 28 antibiotics (aminoglycosides, beta-lactams, macrolides, quinolones, tetracyclines and sulfonamides) against this yeast in whey. For this purpose, the dose-response curve for each antibiotic was constructed using 16 replicates of 12 different concentrations of the antibiotic. The plates were incubated at 40°C until the negative samples exhibited their indicator (5-7h). Subsequently, the abso...
Source: Revista Argentina de Microbiologia - March 12, 2024 Category: Microbiology Authors: Rafael Lisandro Althaus Orlando Guillermo Nagel Dafna Eluk Source Type: research

Viruses, Vol. 16, Pages 432: Torque Teno Virus (TTV) in Renal Transplant Recipients: Species Diversity and Variability
This study aimed to determine the TTV species diversity and variability in renal transplant recipients and to associate species diversity with the corresponding TTV viral load. From 27 recipients, 30 plasma samples were selected. Viral load was determined using two real-time PCR assays, followed by RCA-NGS and ORF1 phylogenetic analysis. The TTV diversity was determined in all samples. Variability was determined in three patients with two sequential samples (pre- and post-transplantation). Most of the samples presented multiple TTV species, up to 15 different species were detected. In the pre-transplant samples (n = 12), t...
Source: Viruses - March 11, 2024 Category: Virology Authors: Noelia Soledad Reyes Pietro Giorgio Spezia Raquel Jara Fabio Filippini Natalia Boccia Gonzalo Garc ía Eliana Hermida Fernando Adrian Poletta Mauro Pistello Gustavo Laham Fabrizio Maggi Marcela Echavarria Tags: Article Source Type: research

The first molecular characterization of Sarcocystis cameli in the Indian dromedary camels (Camelus dromedarius)
AbstractIn the present study, tissue samples (tongue, esophagus and heart) were investigated from dromedary camels of India for identification and characterization ofSarcocystis spp. using histopathology, PCR and gene sequencing. Genomic DNA extracted from these tissue samples was used for PCR amplification of the cytochrome c oxidase subunit I gene (cox1) ofSarcocystis spp. and the partial sequence of small subunit ribosomal RNA (18S rRNA) gene of theS. cameli. The PCR products were purified, sequenced and analyzed using bioinformatics tools. Based on phylogenetic analysis of thecox1 gene, the sequences of the present stu...
Source: Veterinary Research Communications - March 11, 2024 Category: Veterinary Research Source Type: research

Association of PD ‐L1 expression with driver gene mutations and clinicopathological characteristics in non‐small cell lung cancer: A real‐world study of 10 441 patients
ConclusionsPD-L1 expression was associated with well-defined clinicopathological and genomic features. These findings provide a comprehensive view of the expression of PD-L1 in patients with advanced NSCLC in a large Latin American cohort. (Source: Thoracic Cancer)
Source: Thoracic Cancer - March 9, 2024 Category: Cancer & Oncology Authors: Gonzalo Ruiz, Diego Enrico, Yamil D. Mahmoud, Alan Ruiz, Mar ía Florencia Cantarella, Laura Leguina, Mariana Barberis, Asunción Beña, Esteban Brest, Solange Starapoli, Andrea Mendoza Bertelli, Florencia Tsou, Carmen Pupareli, María Pía C Tags: ORIGINAL ARTICLE Source Type: research