A Review on the use of Synthetic and Recombinant Antigens for the Immunodiagnosis of Tegumentary Leishmaniasis
Curr Med Chem. 2024 Mar 19. doi: 10.2174/0109298673298705240311114203. Online ahead of print.ABSTRACTImproving the diagnostic technology used to detect tegumentary leishmaniasis (TL) is essential in view of it being a widespread, often neglected tropical disease with cases reported from the southern United States to northern Argentina. Recombinant proteins, recombinant multiepitope proteins, and synthetic peptides have been extensively researched and used in disease diagnosis. One of the benefits of applying these antigens is a measurable increase in sensitivity and specificity, which improves test accuracy. The present re...
Source: Current Medicinal Chemistry - March 21, 2024 Category: Chemistry Authors: Kamila Silva Anna Julia Ribeiro Isadora Gandra Carlos Rezende Lucas Lopes Carolina Couto Ver ônica Freire Isabelle Barcelos Sabrina Pereira Sandra Xavier Mariana Campos-da-Paz Rodolfo Giunchetti Miguel Ch ávez-Fumagalli Ana Alice Gon çalves Eduardo Coe Source Type: research
A Review on the use of Synthetic and Recombinant Antigens for the Immunodiagnosis of Tegumentary Leishmaniasis
Curr Med Chem. 2024 Mar 19. doi: 10.2174/0109298673298705240311114203. Online ahead of print.ABSTRACTImproving the diagnostic technology used to detect tegumentary leishmaniasis (TL) is essential in view of it being a widespread, often neglected tropical disease with cases reported from the southern United States to northern Argentina. Recombinant proteins, recombinant multiepitope proteins, and synthetic peptides have been extensively researched and used in disease diagnosis. One of the benefits of applying these antigens is a measurable increase in sensitivity and specificity, which improves test accuracy. The present re...
Source: Current Medicinal Chemistry - March 21, 2024 Category: Chemistry Authors: Kamila Silva Anna Julia Ribeiro Isadora Gandra Carlos Rezende Lucas Lopes Carolina Couto Ver ônica Freire Isabelle Barcelos Sabrina Pereira Sandra Xavier Mariana Campos-da-Paz Rodolfo Giunchetti Miguel Ch ávez-Fumagalli Ana Alice Gon çalves Eduardo Coe Source Type: research
A Review on the use of Synthetic and Recombinant Antigens for the Immunodiagnosis of Tegumentary Leishmaniasis
Curr Med Chem. 2024 Mar 19. doi: 10.2174/0109298673298705240311114203. Online ahead of print.ABSTRACTImproving the diagnostic technology used to detect tegumentary leishmaniasis (TL) is essential in view of it being a widespread, often neglected tropical disease with cases reported from the southern United States to northern Argentina. Recombinant proteins, recombinant multiepitope proteins, and synthetic peptides have been extensively researched and used in disease diagnosis. One of the benefits of applying these antigens is a measurable increase in sensitivity and specificity, which improves test accuracy. The present re...
Source: Current Medicinal Chemistry - March 21, 2024 Category: Chemistry Authors: Kamila Silva Anna Julia Ribeiro Isadora Gandra Carlos Rezende Lucas Lopes Carolina Couto Ver ônica Freire Isabelle Barcelos Sabrina Pereira Sandra Xavier Mariana Campos-da-Paz Rodolfo Giunchetti Miguel Ch ávez-Fumagalli Ana Alice Gon çalves Eduardo Coe Source Type: research
A Review on the use of Synthetic and Recombinant Antigens for the Immunodiagnosis of Tegumentary Leishmaniasis
Curr Med Chem. 2024 Mar 19. doi: 10.2174/0109298673298705240311114203. Online ahead of print.ABSTRACTImproving the diagnostic technology used to detect tegumentary leishmaniasis (TL) is essential in view of it being a widespread, often neglected tropical disease with cases reported from the southern United States to northern Argentina. Recombinant proteins, recombinant multiepitope proteins, and synthetic peptides have been extensively researched and used in disease diagnosis. One of the benefits of applying these antigens is a measurable increase in sensitivity and specificity, which improves test accuracy. The present re...
Source: Current Medicinal Chemistry - March 21, 2024 Category: Chemistry Authors: Kamila Silva Anna Julia Ribeiro Isadora Gandra Carlos Rezende Lucas Lopes Carolina Couto Ver ônica Freire Isabelle Barcelos Sabrina Pereira Sandra Xavier Mariana Campos-da-Paz Rodolfo Giunchetti Miguel Ch ávez-Fumagalli Ana Alice Gon çalves Eduardo Coe Source Type: research
Epidemiology and outcomes of pediatric cardiac arrest in a cardiovascular unit at a public hospital in Argentina
CONCLUSIONS: 4.1% of patients presented CRA, with a rate of 3.4 CRA per 1,000 patient-days. Survival at hospital discharge (n = 50) was 46%. Resuscitation > 6 min and the use of vasoactive drugs were independent predictors of mortality. At six months, 63% had normal neurological development for age.PMID:38507335 | DOI:10.24875/ACM.22000237 (Source: Archivos de Cardiologia de Mexico)
Source: Archivos de Cardiologia de Mexico - March 20, 2024 Category: Cardiology Authors: Ricardo Rodr íguez Mar ía Althabe Mar ía Ballestrini Paula Lombardi Ma Bel én Desocio Mariela Krynski Ana M Lenz Mercedes Montonati Guillermo Moreno Ma Lu ísa Pilan Ma Laura Polo Juan C Vassallo Source Type: research
Epidemiology and outcomes of pediatric cardiac arrest in a cardiovascular unit at a public hospital in Argentina
CONCLUSIONS: 4.1% of patients presented CRA, with a rate of 3.4 CRA per 1,000 patient-days. Survival at hospital discharge (n = 50) was 46%. Resuscitation > 6 min and the use of vasoactive drugs were independent predictors of mortality. At six months, 63% had normal neurological development for age.PMID:38507335 | DOI:10.24875/ACM.22000237 (Source: Archivos de Cardiologia de Mexico)
Source: Archivos de Cardiologia de Mexico - March 20, 2024 Category: Cardiology Authors: Ricardo Rodr íguez Mar ía Althabe Mar ía Ballestrini Paula Lombardi Ma Bel én Desocio Mariela Krynski Ana M Lenz Mercedes Montonati Guillermo Moreno Ma Lu ísa Pilan Ma Laura Polo Juan C Vassallo Source Type: research
Epidemiology and outcomes of pediatric cardiac arrest in a cardiovascular unit at a public hospital in Argentina
CONCLUSIONS: 4.1% of patients presented CRA, with a rate of 3.4 CRA per 1,000 patient-days. Survival at hospital discharge (n = 50) was 46%. Resuscitation > 6 min and the use of vasoactive drugs were independent predictors of mortality. At six months, 63% had normal neurological development for age.PMID:38507335 | DOI:10.24875/ACM.22000237 (Source: Archivos de Cardiologia de Mexico)
Source: Archivos de Cardiologia de Mexico - March 20, 2024 Category: Cardiology Authors: Ricardo Rodr íguez Mar ía Althabe Mar ía Ballestrini Paula Lombardi Ma Bel én Desocio Mariela Krynski Ana M Lenz Mercedes Montonati Guillermo Moreno Ma Lu ísa Pilan Ma Laura Polo Juan C Vassallo Source Type: research
Epidemiology and outcomes of pediatric cardiac arrest in a cardiovascular unit at a public hospital in Argentina
CONCLUSIONS: 4.1% of patients presented CRA, with a rate of 3.4 CRA per 1,000 patient-days. Survival at hospital discharge (n = 50) was 46%. Resuscitation > 6 min and the use of vasoactive drugs were independent predictors of mortality. At six months, 63% had normal neurological development for age.PMID:38507335 | DOI:10.24875/ACM.22000237 (Source: Archivos de Cardiologia de Mexico)
Source: Archivos de Cardiologia de Mexico - March 20, 2024 Category: Cardiology Authors: Ricardo Rodr íguez Mar ía Althabe Mar ía Ballestrini Paula Lombardi Ma Bel én Desocio Mariela Krynski Ana M Lenz Mercedes Montonati Guillermo Moreno Ma Lu ísa Pilan Ma Laura Polo Juan C Vassallo Source Type: research
Epidemiology and outcomes of pediatric cardiac arrest in a cardiovascular unit at a public hospital in Argentina
CONCLUSIONS: 4.1% of patients presented CRA, with a rate of 3.4 CRA per 1,000 patient-days. Survival at hospital discharge (n = 50) was 46%. Resuscitation > 6 min and the use of vasoactive drugs were independent predictors of mortality. At six months, 63% had normal neurological development for age.PMID:38507335 | DOI:10.24875/ACM.22000237 (Source: Archivos de Cardiologia de Mexico)
Source: Archivos de Cardiologia de Mexico - March 20, 2024 Category: Cardiology Authors: Ricardo Rodr íguez Mar ía Althabe Mar ía Ballestrini Paula Lombardi Ma Bel én Desocio Mariela Krynski Ana M Lenz Mercedes Montonati Guillermo Moreno Ma Lu ísa Pilan Ma Laura Polo Juan C Vassallo Source Type: research
Fundus topographical distribution patterns of ocular toxoplasmosis
Conclusion
The 1° lesions were larger than 2° lesions. The 2° lesions were not significantly closer to fovea than 1° lesions. Temporal quadrant and macular region were found to be densely affected underlining the vision threatening nature of the disease. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Hasanreisoglu, M., Halim, M. S., Cakar Ozdal, P., Ormaechea, M. S., Kesim, C., Ozdemir, H. B., Uludag, G., Sredar, N., Cankurtaran, M., Liu, X., Denniston, A. K., Rudzinski, M. N., Colombero, D. N., Schlaen, B. A., Keane, P. A., Pavesio, C., Nguyen, Q. D. Tags: Inflammatory eye disease Source Type: research
Genome sequencing and analysis of black flounder (Paralichthys orbignyanus) reveals new insights into Pleuronectiformes genomic size and structure
Black flounder (Paralichthys orbignyanus, Pleuronectiformes) is a commercially significant marine fish with promising aquaculture potential in Argentina. Despite extensive studies on Black flounder aquaculture, i... (Source: BMC Genomics)
Source: BMC Genomics - March 20, 2024 Category: Genetics & Stem Cells Authors: Fernando Villarreal, Germ án F. Burguener, Ezequiel J. Sosa, Nicolas Stocchi, Gustavo M. Somoza, Adrián G. Turjanski, Andrés Blanco, Jordi Viñas and Alejandro S. Mechaly Tags: Research Source Type: research
Scientists in Antarctica track ‘baffling’ virus that could decimate penguins and other polar animals
A 23-meter-long sailboat set off last week from Argentina for Antarctica’s Weddell Sea with eight scientists, lots of cloacal swabs, and a genetic fingerprinting machine aboard. The
Australis
is headed for the southern continent’s teeming colonies of Adélie penguins, other seabirds, and marine mammals. The
goal
: to search for signs of a deadly virus that has nearly circled the world over the past 4 years, leaving behind a trail of devastated wildlife.
Last month, Spanish researchers
confirmed
that H5N1, the highly pathogenic form of avian influenza, had finally turned up—as long ...
Source: Science of Aging Knowledge Environment - March 18, 2024 Category: Geriatrics Source Type: research
Acute viral hepatitis: What we do know and still do not know about hepatitis A and E in Argentina
Rev Argent Microbiol. 2024 Jan-Mar;56(1):1-3. doi: 10.1016/j.ram.2024.03.001.NO ABSTRACTPMID:38499433 | DOI:10.1016/j.ram.2024.03.001 (Source: Revista Argentina de Microbiologia)
Source: Revista Argentina de Microbiologia - March 18, 2024 Category: Microbiology Authors: Maria Laura Minassian Source Type: research
