Trends, Patterns and Associated User Characteristics of Antidepressant Prescriptions in Older Adults: A Nationwide Descriptive Cohort Study in Denmark
ConclusionSSRIs were the most commonly redeemed antidepressants, with consistent trends in Danish older adults. Besides clinical conditions, sociodemographics, e.g., sex, age, ethnicity, and place of residence, may influence antidepressant use. (Source: Drugs and Aging)
Source: Drugs and Aging - March 15, 2023 Category: Geriatrics Source Type: research
Therapeutic potential of amitriptyline for paraquat-induced pulmonary fibrosis: Involvement of caveolin-1-mediated anti-epithelial-mesenchymal transition and inhibition of apoptosis
CONCLUSION: AMT inhibited PQ-induced EMT in A549 cells and improved lung histopathology and oxygenation in mice by up-regulating caveolin-1.PMID:36898313 | DOI:10.1016/j.ecoenv.2023.114732 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - March 10, 2023 Category: Environmental Health Authors: Jianshi Chen Xiangdong Jian Chunmei Li Bihuang Cheng Source Type: research
Anticancer Effects of Antidepressants in Hepatocellular Carcinoma Cells
CONCLUSION: According to previous and present findings, TCAs, SSRIs and mianserin may have anti-tumor activity in HCC. However, the appropriate dose, frequency, and route of the administration still need to be determined in future preclinical and clinical studies.PMID:36854516 | DOI:10.21873/anticanres.16266 (Source: Cell Research)
Source: Cell Research - February 28, 2023 Category: Cytology Authors: Ya-Hui Huang Chau-Ting Yeh Source Type: research
Neuromodulating agents in functional dyspepsia: a comprehensive review
CONCLUSION: Selected neuromodulators have an established efficacy in functional dyspepsia. The best supporting evidence is available for TCAs with a potential role for tetracyclic antidepressants, levosulpiride and anxiolytics.PMID:36842175 | DOI:10.51821/86.1.10998 (Source: Acta Gastro-Enterologica Belgica)
Source: Acta Gastro-Enterologica Belgica - February 26, 2023 Category: Gastroenterology Authors: L Bosman L Wauters T Vanuytsel Source Type: research
