Challenges in the management of new daily persistent headache at a tertiary headache center-A retrospective real-world evidence study
CONCLUSION: In this study we add real-world evidence to suggest that prophylactic drugs conventionally used for treating chronic migraine and chronic tension-type headache have limited utility for treating NDPH; however, a partial response in 26% of patients using candesartan and 15% of patients using mirtazapine warrants further investigation in randomized double-blinded placebo-controlled trials.PMID:38646979 | DOI:10.1111/head.14715 (Source: Headache)
Source: Headache - April 22, 2024 Category: Neurology Authors: Thor Linnet Marwa Hussein Henrik Winther Schytz Lars Bendtsen Faisal Mohammad Amin Source Type: research

Effectiveness of Antidepressants in Combination with Psychotherapy
This study reports the remission rates for the 14 most commonly prescribed single antidepressants (amitriptyline, bupropion, citalopram, desvenlafaxine, doxepin, duloxetine, escitalopram, fluoxetine, mirtazapine, nortriptyline, paroxetine, sertraline, trazodone, and venlafaxine) and a category named "Other" (other antidepressants/combination of antidepressants). The study used robust LASSO regressions to identify factors that affected remission rate and clinicians' selection of antidepressants. The selection bias in observational data was removed through stratification. We organized the data into 16,770 subgroups, of at le...
Source: Journal of Mental Health Policy and Economics - April 18, 2024 Category: Psychiatry Authors: Farrokh Alemi Tulay G Soylu Mary Cannon Conor McCandless Source Type: research

Spinal neuronal activity and neuroinflammatory component in a mouse model of CFA-induced vestibulodynia
In conclusion, our study provides a comprehensive understanding of the CFA-induced model of vestibulodynia, encompassing behavioral, neurophysiological and neuroinflammatory aspects. These data pave the way to investigate spinal cord first pain plasticity in vestibulodynia.PMID:38636564 | DOI:10.1016/j.bbi.2024.04.012 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - April 18, 2024 Category: Neurology Authors: Serena Boccella Michela Perrone Antimo Fusco Roozbe Bonsale Rosmara Infantino Silvia Nuzzo Giovanni Pecoraro Federica Ricciardi Andrea Maria Morace Gianluca Petrillo Ilaria Leone Monica Franzese Vito de Novellis Francesca Guida Marco Salvatore Sabatino Ma Source Type: research

Effectiveness of Antidepressants in Combination with Psychotherapy
This study reports the remission rates for the 14 most commonly prescribed single antidepressants (amitriptyline, bupropion, citalopram, desvenlafaxine, doxepin, duloxetine, escitalopram, fluoxetine, mirtazapine, nortriptyline, paroxetine, sertraline, trazodone, and venlafaxine) and a category named "Other" (other antidepressants/combination of antidepressants). The study used robust LASSO regressions to identify factors that affected remission rate and clinicians' selection of antidepressants. The selection bias in observational data was removed through stratification. We organized the data into 16,770 subgroups, of at le...
Source: Journal of Mental Health Policy and Economics - April 18, 2024 Category: Psychiatry Authors: Farrokh Alemi Tulay G Soylu Mary Cannon Conor McCandless Source Type: research

Clinical effects of combined use of carbamazepine and amitriptyline in the treatment of diabetic neuropathy with concurrent diabetic foot
. (Source: International Journal of Neuroscience)
Source: International Journal of Neuroscience - April 17, 2024 Category: Neuroscience Authors: Yi ChenLan LiuXiangjing KongJinshan SunHuijun LiXue ChangJianfang Chea Department of Anesthesiology, Nanjing Hospital of Chinese Medicine, Nanjing, Jiangsu, Chinab Department of Endocrinology, The Air Force Hospital from Eastern Theater of PLA, Nanjing, J Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Les meilleures études en 2023 adaptées aux soins primaires: De l’équipe du groupe PEER
CONCLUSION: La recherche publiée en 2023 a produit plusieurs articles de grande qualité sur divers sujets d’intérêt en soins primaires, dont les soins cardiovasculaires, le syndrome du côlon irritable, les soins aux aînés et la prise en charge de l’acné.PMID:38626994 | DOI:10.46747/cfp.7004e47 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Pain Physician)
Source: Pain Physician - April 16, 2024 Category: Anesthesiology Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Les meilleures études en 2023 adaptées aux soins primaires: De l’équipe du groupe PEER
CONCLUSION: La recherche publiée en 2023 a produit plusieurs articles de grande qualité sur divers sujets d’intérêt en soins primaires, dont les soins cardiovasculaires, le syndrome du côlon irritable, les soins aux aînés et la prise en charge de l’acné.PMID:38626994 | DOI:10.46747/cfp.7004e47 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research

Gastroenterology/Hepatology: What You May Have Missed in 2023
This article summarizes clinically important gastroenterology developments from 2023 for internal medicine specialists. In colorectal cancer screening, a new RNA fecal screening test is on the horizon, as well as a new analysis on the benefits of using artificial intelligence in screening colonoscopy to detect more polyps. There is new evidence for management of gastrointestinal bleeding, a new drug for treatment of recurrent small-intestinal angiodysplasia, and a new endoscopic treatment method in patients with gastrointestinal tumor bleeding. The authors feature a randomized trial about amitriptyline as treatment for pat...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Sama Anvari Kayla Dadgar Ciar án Galts Michael Bretthauer Source Type: research

Gastroenterology/Hepatology: What You May Have Missed in 2023
This article summarizes clinically important gastroenterology developments from 2023 for internal medicine specialists. In colorectal cancer screening, a new RNA fecal screening test is on the horizon, as well as a new analysis on the benefits of using artificial intelligence in screening colonoscopy to detect more polyps. There is new evidence for management of gastrointestinal bleeding, a new drug for treatment of recurrent small-intestinal angiodysplasia, and a new endoscopic treatment method in patients with gastrointestinal tumor bleeding. The authors feature a randomized trial about amitriptyline as treatment for pat...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Sama Anvari Kayla Dadgar Ciar án Galts Michael Bretthauer Source Type: research

Gastroenterology/Hepatology: What You May Have Missed in 2023
This article summarizes clinically important gastroenterology developments from 2023 for internal medicine specialists. In colorectal cancer screening, a new RNA fecal screening test is on the horizon, as well as a new analysis on the benefits of using artificial intelligence in screening colonoscopy to detect more polyps. There is new evidence for management of gastrointestinal bleeding, a new drug for treatment of recurrent small-intestinal angiodysplasia, and a new endoscopic treatment method in patients with gastrointestinal tumor bleeding. The authors feature a randomized trial about amitriptyline as treatment for pat...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Sama Anvari Kayla Dadgar Ciar án Galts Michael Bretthauer Source Type: research