Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

Amitriptyline as Second-Line Therapy Improves Symptoms in Adults With Irritable Bowel Syndrome
Am Fam Physician. 2024 Mar;109(3):Online.NO ABSTRACTPMID:38574228 (Source: American Family Physician)
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Henry C Barry Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

Amitriptyline as Second-Line Therapy Improves Symptoms in Adults With Irritable Bowel Syndrome
Am Fam Physician. 2024 Mar;109(3):Online.NO ABSTRACTPMID:38574228 (Source: American Family Physician)
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Henry C Barry Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

Amitriptyline as Second-Line Therapy Improves Symptoms in Adults With Irritable Bowel Syndrome
Am Fam Physician. 2024 Mar;109(3):Online.NO ABSTRACTPMID:38574228 (Source: American Family Physician)
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Henry C Barry Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

Amitriptyline as Second-Line Therapy Improves Symptoms in Adults With Irritable Bowel Syndrome
Am Fam Physician. 2024 Mar;109(3):Online.NO ABSTRACTPMID:38574228 (Source: American Family Physician)
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Henry C Barry Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

Amitriptyline as Second-Line Therapy Improves Symptoms in Adults With Irritable Bowel Syndrome
Am Fam Physician. 2024 Mar;109(3):Online.NO ABSTRACTPMID:38574228 (Source: American Family Physician)
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Henry C Barry Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

Use of antidepressants in the treatment of chronic orofacial pain caused by temporomandibular disorders: A randomized controlled clinical trial
CONCLUSIONS: Low doses of amitriptyline appear to be a good therapeutic option in patients with TMDs suffering from chronic orofacial pain.PMID:38570297 | DOI:10.1016/j.medcli.2024.02.002 (Source: Medicina Clinica)
Source: Medicina Clinica - April 3, 2024 Category: General Medicine Authors: Bruno Macedo de Sousa Antonio L ópez-Valverde Francisco Caramelo Maria Joao Rodrigues Nansi L ópez-Valverde Source Type: research

Chinese herbal medicines for the treatment of depression: a systematic review and network meta-analysis
Conclusion: Our findings elucidate the promising therapeutic potential of Chinese herbal medicines as viable alternatives in the treatment of depression, with certain herbs demonstrating enhanced efficacy and safety profiles. The outcomes of this study advocate for the integration of these alternative modalities into contemporary depression management paradigms. However, it underscores the necessity for larger, methodologically robust trials to further validate and refine these preliminary findings.Systematic review registration:https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42023452109. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - April 3, 2024 Category: Drugs & Pharmacology Source Type: research

Combination of pregabalin and Amitriptyline in management of chronic idiopathic pain following penile prosthesis implantation: a pilot study
ConclusionThe combination of pregabalin and amitriptyline is very effective in the management of chronic idiopathic pain following penile prosthesis implantation. However, due to the ambiguity and lack of reporting of the condition, we recommend a multicentric contribution to acknowledge the condition, and weigh its prevalence accurately, whilst evaluating the efficacy of our approach.This study received ethical approval from Ain Shams University Research Ethics Committee (REC) FWA 000017585, on 04/13/2023 (REC-FMASU@med.asu.edu.eg).Trial registrationno FMASU R98/2023. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - April 2, 2024 Category: Urology & Nephrology Source Type: research