Alopecia Areata Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Review of global epidemiology data for Alopecia Areata highlights gaps and a call for action
Br J Dermatol. 2024 Mar 1:ljae088. doi: 10.1093/bjd/ljae088. Online ahead of print.NO ABSTRACTPMID:38426530 | DOI:10.1093/bjd/ljae088 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - March 1, 2024 Category: Dermatology Authors: Cathryn Sibbald Leslie Castelo-Soccio Source Type: research

Role of systemic minoxidil in the treatment of alopecia areata: a scoping review to direct future research
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - February 27, 2024 Category: Dermatology Authors: Emadodin Darchini-Maragheh, Huw Rees, Anthony Moussa, Laita Bokhari, Leslie Jones, Rodney Sinclair Source Type: research

Clinical and sociodemographic features of alopecia areata in five Colombian cities: an analysis of the RENAAC registry
Conclusions: AA was slightly predominant in women. As seen in other populations, this disease had an earlier onset in men vs women. Presentation in pediatric age was uncommon. The previous history of other dermatological diseases was checked in almost one third of the patients. Analysis of the co-presentation of AA with other autoimmune diseases is biased due to excluding patients with systemic erythematous lupus from the study.PMID:38395225 | DOI:10.1016/j.ad.2024.02.018 (Source: Actas Dermo-Sifiliograficas)
Source: Actas Dermo-Sifiliograficas - February 23, 2024 Category: Dermatology Authors: J C Pineda N R Alvis-Zakzuka L Moyano-T ámara J Fierro-Lozada C Cera-Coll W Celorio-Murillo N J Alvis-Zakzuk J Zapata-Ospina J F Ruiz-G ómez J Zakzuk N Alvis-Guzm ána D Castillo-Molina Source Type: research

Etrasimod: First Approval
This article summarises the milestones in the development of etrasimod leading to this first approval for the treatment of ulcer ative colitis in adults. (Source: Drugs)
Source: Drugs - February 23, 2024 Category: Drugs & Pharmacology Source Type: research

The role of laser and energy-assisted drug delivery in the treatment of alopecia
AbstractIt has been recently established that laser treatment can be combined with topical or intralesional medications to enhance the delivery of drugs and improve overall results in a variety of different dermatological disorders. The aim of this review is to evaluate the use of laser and energy-assisted drug delivery (LEADD) for the treatment of alopecia with a specific focus on ablative fractional lasers (AFL), non-ablative fractional lasers (NAFL), and radiofrequency microneedling (RFMN). A comprehensive PubMed search was performed in December 2022 for “laser-assisted drug delivery” as well as “laser” and “a...
Source: Lasers in Medical Science - February 21, 2024 Category: Laser Surgery Source Type: research

Decreased CD19+CD24hiCD38hi Regulatory B cells in Alopecia Areata
Regulatory B cells (Bregs) produce anti-inflammatory factors, such as IL-10, IL-35, and TGF- β, and exert immunosuppressive effects in autoimmune diseases by inducing regulatory T cells.(Rosser and Mauri, 2015) Deficiency of Bregs, particularly the IL-10-producing subset, has been implicated in several autoimmune diseases involving cutaneous manifestations, such as lupus erythematosus, pso riasis and atopic dermatitis.(Wang et al., 2020) However, their role in alopecia areata (AA), an autoimmune disease involving hair follicles, is unclear. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - February 20, 2024 Category: Dermatology Authors: Jong Yeong Lee, Hyo Jung Lim, Sang-Hyun Kim, Geon-Jong Lee, Kyung-Hwa Nam, Jin Park, Jin Kyeong Choi Tags: Letters to the Editor Source Type: research

Alopecia areata and comorbidities associated with it in Germany
Br J Dermatol. 2024 Feb 16;190(3):e32. doi: 10.1093/bjd/ljae027.NO ABSTRACTPMID:38366836 | DOI:10.1093/bjd/ljae027 (Source: The British Journal of Dermatology)
Source: The British Journal of Dermatology - February 17, 2024 Category: Dermatology Source Type: research

Moving Beyond Boundaries: Utilization of Longitudinal Exposure –Response Model for Bounded Outcome Score to Inform Decision Making in the Accelerated Drug Development Paradigm
ConclusionThe CBO modeling approach and simulation supported the single pivotal trial strategy and guided dose selection in the accelerated drug development program of ritlecitinib, which can be applied to many indications where efficacy is measured on a bounded scale. (Source: Clinical Pharmacokinetics)
Source: Clinical Pharmacokinetics - February 15, 2024 Category: Drugs & Pharmacology Source Type: research

Dupliumab therapy for alopecia areata: a case series and review of the literature
CONCLUSIONS: Overall, our research supports dupilumab as another candidate that possesses potential benefits for AA. High levels of IgE may be not prerequisites for dupilumab's successful treatment response.PMID:38342501 | DOI:10.1080/09546634.2024.2312245 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - February 11, 2024 Category: Dermatology Authors: Jundong Huang Jia Jian Tingting Li Min Li Kaifu Luo Sihan Deng Yan Tang Fangfen Liu Zhixiang Zhao Wei Shi Ji Li Source Type: research