Potential Indications of Dupilumab in Th-2 Inflammatory Disease
Rev Recent Clin Trials. 2023 Dec 20. doi: 10.2174/0115748871263396231121060901. Online ahead of print.ABSTRACTDupilumab is a fully humanized IgG4 monoclonal antibody, inhibiting IL-4 and IL-13 signaling, which are the main cytokines involved in type 2 inflammatory diseases. Its introduction was a breakthrough in the treatment of moderate-to-severe atopic dermatitis, but it is also used in other inflammatory diseases, including asthma, eosinophilic esophagitis and chronic rhinosinusitis with nasal polyposis. Recent advances in the understanding of inflammatory pathways have revealed that Th2-type inflammation is involved in...
Source: Reviews on Recent Clinical Trials - December 23, 2023 Category: Cancer & Oncology Authors: Proietti Ilaria Skroza Nevena Tolino Ersilia Bernardini Nicoletta Federica Trovato Marco Di Fraia Dybala Agniezska Potenza Concetta Source Type: research

Potential Indications of Dupilumab in Th-2 Inflammatory Disease
Rev Recent Clin Trials. 2023 Dec 20. doi: 10.2174/0115748871263396231121060901. Online ahead of print.ABSTRACTDupilumab is a fully humanized IgG4 monoclonal antibody, inhibiting IL-4 and IL-13 signaling, which are the main cytokines involved in type 2 inflammatory diseases. Its introduction was a breakthrough in the treatment of moderate-to-severe atopic dermatitis, but it is also used in other inflammatory diseases, including asthma, eosinophilic esophagitis and chronic rhinosinusitis with nasal polyposis. Recent advances in the understanding of inflammatory pathways have revealed that Th2-type inflammation is involved in...
Source: Reviews on Recent Clinical Trials - December 23, 2023 Category: Cancer & Oncology Authors: Proietti Ilaria Skroza Nevena Tolino Ersilia Bernardini Nicoletta Federica Trovato Marco Di Fraia Dybala Agniezska Potenza Concetta Source Type: research

Potential Indications of Dupilumab in Th-2 Inflammatory Disease
Rev Recent Clin Trials. 2023 Dec 20. doi: 10.2174/0115748871263396231121060901. Online ahead of print.ABSTRACTDupilumab is a fully humanized IgG4 monoclonal antibody, inhibiting IL-4 and IL-13 signaling, which are the main cytokines involved in type 2 inflammatory diseases. Its introduction was a breakthrough in the treatment of moderate-to-severe atopic dermatitis, but it is also used in other inflammatory diseases, including asthma, eosinophilic esophagitis and chronic rhinosinusitis with nasal polyposis. Recent advances in the understanding of inflammatory pathways have revealed that Th2-type inflammation is involved in...
Source: Reviews on Recent Clinical Trials - December 23, 2023 Category: Cancer & Oncology Authors: Proietti Ilaria Skroza Nevena Tolino Ersilia Bernardini Nicoletta Federica Trovato Marco Di Fraia Dybala Agniezska Potenza Concetta Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

Application of validated UV spectrophotometric and colorimetric method to quantify minoxidil in the development of trilayer dissolving microneedle: Proof of concept in ex vivo and in vivo studies in rats
In conclusion, TDMN holds promise for enhancing MNX delivery, mitigating bioavailability and side effect challenges. The validated UV-Vis Spectrophotometer method effectively analyzes MNX in skin tissues, providing insights into AA treatment and establishing a robust analytical foundation for future studies.PMID:38135037 | DOI:10.1016/j.pharma.2023.12.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 22, 2023 Category: Drugs & Pharmacology Authors: Nur Afika Afifah Fadhilah Saniy Athaullah Akmal Fawwaz D Christopher Kosasi Ko Rayu Kamran Andi Dian Permana Source Type: research

Cutaneous manifestations of the COVID-19 pandemic in schoolchildren and adolescents
Acta Dermatovenerol Alp Pannonica Adriat. 2023 Dec;32(4):173-181.ABSTRACTThis review article focuses on cutaneous manifestations in schoolchildren and adolescents 6 to 18 years old connected with various aspects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, including personal protective equipment (PPE), SARS-CoV-2 infection, and the SARS-CoV-2 vaccine. The use of PPE has been associated with mask-related acne due to microbiome dysbiosis and disruption of skin homeostasis, leading to the emergence of new acne or exacerbation of preexisting acne. Chilblain-like lesions, erythema multiforme-lik...
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - December 21, 2023 Category: Dermatology Authors: Daniela Franuli ć Ena Para ć Lorena Dola čki Iva Topalu šić Liborija Lugovi ć-Mihić Source Type: research