Effectiveness and Predictive Factors of Response to Tofacitinib Therapy in 125 Patients with Alopecia Areata: A Single-centre Real-world Retrospective Study
This study suggests that tofacitinib provides an effective treatment option for patients with alopecia areata, and that earlier intervention in the treatment of severe alopecia areata with tofacitinib may lead to better outcomes.PMID:38112208 | DOI:10.2340/actadv.v103.12425 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - December 19, 2023 Category: Dermatology Authors: Jundong Huang Pei Qian Yan Tang Ji Li Fangfen Liu Wei Shi Source Type: research
Effectiveness and Predictive Factors of Response to Tofacitinib Therapy in 125 Patients with Alopecia Areata: A Single-centre Real-world Retrospective Study
This study suggests that tofacitinib provides an effective treatment option for patients with alopecia areata, and that earlier intervention in the treatment of severe alopecia areata with tofacitinib may lead to better outcomes.PMID:38112208 | DOI:10.2340/actadv.v103.12425 (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - December 19, 2023 Category: Dermatology Authors: Jundong Huang Pei Qian Yan Tang Ji Li Fangfen Liu Wei Shi Source Type: research
Effectiveness and Predictive Factors of Response to Tofacitinib Therapy in 125 Patients with Alopecia Areata: A Single-centre Real-world Retrospective Study
This study suggests that tofacitinib provides an effective treatment option for patients with alopecia areata, and that earlier intervention in the treatment of severe alopecia areata with tofacitinib may lead to better outcomes.PMID:38112208 | DOI:10.2340/actadv.v103.12425 (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - December 19, 2023 Category: Dermatology Authors: Jundong Huang Pei Qian Yan Tang Ji Li Fangfen Liu Wei Shi Source Type: research
Effectiveness and Predictive Factors of Response to Tofacitinib Therapy in 125 Patients with Alopecia Areata: A Single-centre Real-world Retrospective Study
This study suggests that tofacitinib provides an effective treatment option for patients with alopecia areata, and that earlier intervention in the treatment of severe alopecia areata with tofacitinib may lead to better outcomes.PMID:38112208 | DOI:10.2340/actadv.v103.12425 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - December 19, 2023 Category: Dermatology Authors: Jundong Huang Pei Qian Yan Tang Ji Li Fangfen Liu Wei Shi Source Type: research
Editors ’ Picks
Alopecia areata (AA) is a CD8+ T-cell –mediated chronic inflammatory disease that results in rapid onset of hair loss, although the specific CD8+ T cells involved in pathogenesis remain unknown. To delineate the responsible cell type, Seok et al (2023) investigated the role of virtual memory T (TVM) cells, which exhibit a memory phen otype in the absence of foreign antigen exposure and are thought to promote antibacterial, antiviral, and antitumor immunity. The TVM population from mice with AA yielded 2 subsets: CD44super hi (s-hi)CD49dloCD8+ T cells and CD44hiCD49dloCD8+ conventional TVM cells. (Source: Journal of Inve...
Source: Journal of Investigative Dermatology - December 15, 2023 Category: Dermatology Tags: Editors' Picks Source Type: research
Molecules, Vol. 28, Pages 8064: Novel Janus Kinase Inhibitors in the Treatment of Dermatologic Conditions
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Janus kinase inhibitors, also known as JAK inhibitors, JAKinibs or JAKi, are a new group of disease-modifying drugs. They work by inhibiting enzymes involved in the transmission of information from receptors located in the cell membrane to the cell interior, specifically to the cell nucleus, thus disrupting the JAK-STAT pathway. This pathway plays a role in key cellular processes such as the immune response and cell growth. This feature is used in the treatment of patients with rheumatological, gastroenterological and hematological diseases. Recently, it has been discovered that JAK-STAT pathway inhibitors also sho...
Source: Molecules - December 13, 2023 Category: Chemistry Authors: Izabella Rygu ła Wojciech Pikiewicz Konrad Kamini ów Tags: Review Source Type: research
Hair Regrowth Outcomes of Superficial Cryotherapy in Patients with Alopecia Areata: A Systematic Review
Ann Dermatol. 2023 Dec;35(6):464-467. doi: 10.5021/ad.22.095.NO ABSTRACTPMID:38086361 | DOI:10.5021/ad.22.095 (Source: Annals of Dermatology)
Source: Annals of Dermatology - December 12, 2023 Category: Dermatology Authors: Sung Ha Lim Won-Soo Lee Source Type: research
