Knowledge of and stated adherence to the 2020 ACR Guideline for Gout Management: Results of a survey of US rheumatologists
CONCLUSION: The self-reported practice of the surveyed US rheumatologists was generally concordant with the 2020 ACR Guideline for the Management of Gout. However, there were gaps in guideline knowledge and stated adherence among rheumatologists, mainly concerning the dosing of treatment regimens.PMID:38621796 | DOI:10.3899/jrheum.2023-0981 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Naomi Schlesinger Michael H Pillinger Peter E Lipsky Source Type: research

Knowledge of and stated adherence to the 2020 ACR Guideline for Gout Management: Results of a survey of US rheumatologists
CONCLUSION: The self-reported practice of the surveyed US rheumatologists was generally concordant with the 2020 ACR Guideline for the Management of Gout. However, there were gaps in guideline knowledge and stated adherence among rheumatologists, mainly concerning the dosing of treatment regimens.PMID:38621796 | DOI:10.3899/jrheum.2023-0981 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Naomi Schlesinger Michael H Pillinger Peter E Lipsky Source Type: research

Knowledge of and stated adherence to the 2020 ACR Guideline for Gout Management: Results of a survey of US rheumatologists
CONCLUSION: The self-reported practice of the surveyed US rheumatologists was generally concordant with the 2020 ACR Guideline for the Management of Gout. However, there were gaps in guideline knowledge and stated adherence among rheumatologists, mainly concerning the dosing of treatment regimens.PMID:38621796 | DOI:10.3899/jrheum.2023-0981 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Naomi Schlesinger Michael H Pillinger Peter E Lipsky Source Type: research

Knowledge of and stated adherence to the 2020 ACR Guideline for Gout Management: Results of a survey of US rheumatologists
CONCLUSION: The self-reported practice of the surveyed US rheumatologists was generally concordant with the 2020 ACR Guideline for the Management of Gout. However, there were gaps in guideline knowledge and stated adherence among rheumatologists, mainly concerning the dosing of treatment regimens.PMID:38621796 | DOI:10.3899/jrheum.2023-0981 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Naomi Schlesinger Michael H Pillinger Peter E Lipsky Source Type: research

Knowledge of and stated adherence to the 2020 ACR Guideline for Gout Management: Results of a survey of US rheumatologists
CONCLUSION: The self-reported practice of the surveyed US rheumatologists was generally concordant with the 2020 ACR Guideline for the Management of Gout. However, there were gaps in guideline knowledge and stated adherence among rheumatologists, mainly concerning the dosing of treatment regimens.PMID:38621796 | DOI:10.3899/jrheum.2023-0981 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Naomi Schlesinger Michael H Pillinger Peter E Lipsky Source Type: research

Knowledge of and stated adherence to the 2020 ACR Guideline for Gout Management: Results of a survey of US rheumatologists
CONCLUSION: The self-reported practice of the surveyed US rheumatologists was generally concordant with the 2020 ACR Guideline for the Management of Gout. However, there were gaps in guideline knowledge and stated adherence among rheumatologists, mainly concerning the dosing of treatment regimens.PMID:38621796 | DOI:10.3899/jrheum.2023-0981 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Naomi Schlesinger Michael H Pillinger Peter E Lipsky Source Type: research

Knowledge of and stated adherence to the 2020 ACR Guideline for Gout Management: Results of a survey of US rheumatologists
CONCLUSION: The self-reported practice of the surveyed US rheumatologists was generally concordant with the 2020 ACR Guideline for the Management of Gout. However, there were gaps in guideline knowledge and stated adherence among rheumatologists, mainly concerning the dosing of treatment regimens.PMID:38621796 | DOI:10.3899/jrheum.2023-0981 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2024 Category: Rheumatology Authors: Naomi Schlesinger Michael H Pillinger Peter E Lipsky Source Type: research

Knowledge of and stated adherence to the 2020 ACR Guideline for Gout Management: Results of a survey of US rheumatologists
CONCLUSION: The self-reported practice of the surveyed US rheumatologists was generally concordant with the 2020 ACR Guideline for the Management of Gout. However, there were gaps in guideline knowledge and stated adherence among rheumatologists, mainly concerning the dosing of treatment regimens.PMID:38621796 | DOI:10.3899/jrheum.2023-0981 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2024 Category: Rheumatology Authors: Naomi Schlesinger Michael H Pillinger Peter E Lipsky Source Type: research

Tumor lysis syndrome in induction therapy for acute myeloid leukemia before the rasburicase era
Int J Hematol. 2024 Apr 5. doi: 10.1007/s12185-024-03752-w. Online ahead of print.ABSTRACTGuidelines recommend rasburicase for high-risk patients to prevent tumor lysis syndrome (TLS). However, little information is available on the incidence and outcome of TLS in AML patients. We analyzed 145 patients with AML who underwent induction therapy before the approval of rasburicase to evaluate the incidence of TLS and the necessity of rasburicase as prophylaxis. Three patients had already developed clinical TLS (CTLS) at diagnosis of AML, and another three developed CTLS after the initiation of chemotherapy. In patients without...
Source: International Journal of Hematology - April 4, 2024 Category: Hematology Authors: Yumiko Toda Masahiro Ashizawa Rui Murahashi Hirotomo Nakashima Takashi Ikeda Shin-Ichiro Kawaguchi Takashi Nagayama Kento Umino Daisuke Minakata Kaoru Morita Chihiro Yamamoto Kaoru Hatano Kazuya Sato Shin-Ichiro Fujiwara Ken Ohmine Yoshinobu Kanda Source Type: research

Tumor lysis syndrome in induction therapy for acute myeloid leukemia before the rasburicase era
Int J Hematol. 2024 Apr 5. doi: 10.1007/s12185-024-03752-w. Online ahead of print.ABSTRACTGuidelines recommend rasburicase for high-risk patients to prevent tumor lysis syndrome (TLS). However, little information is available on the incidence and outcome of TLS in AML patients. We analyzed 145 patients with AML who underwent induction therapy before the approval of rasburicase to evaluate the incidence of TLS and the necessity of rasburicase as prophylaxis. Three patients had already developed clinical TLS (CTLS) at diagnosis of AML, and another three developed CTLS after the initiation of chemotherapy. In patients without...
Source: International Journal of Hematology - April 4, 2024 Category: Hematology Authors: Yumiko Toda Masahiro Ashizawa Rui Murahashi Hirotomo Nakashima Takashi Ikeda Shin-Ichiro Kawaguchi Takashi Nagayama Kento Umino Daisuke Minakata Kaoru Morita Chihiro Yamamoto Kaoru Hatano Kazuya Sato Shin-Ichiro Fujiwara Ken Ohmine Yoshinobu Kanda Source Type: research

Anti-gouty arthritis and anti-inflammatory effects of curcumin nanoparticles in monosodium urate crystals induced Balb/C mice
This study aimed to investigate anti-gout and anti-inflammatory properties of curcumin nanoparticles (CNPs). For this purpose, CNPs were prepared by dissolving curcumin into dichloromethane. Then, gout was induced by injecting monosodium urate crystals (MSU) in the ankle joint and in the intra-per itoneal cavity which caused ankle swelling and increased blood uric acid levels. CNPs in different concentrations (5, 10, and 20 ppm) and allopurinol were orally administered. The MSU crystals increased the xanthine oxidase levels both in serum and the liver. Moreover, MSU crystals increased the se rum levels of interleukin 1β,...
Source: Inflammopharmacology - March 31, 2024 Category: Drugs & Pharmacology Source Type: research

Stevens-Johnson syndrome and toxic epidermal necrolysis in Hong Kong
CONCLUSION: This study showed that SJS/TEN are uncommon in Hong Kong but can cause substantial morbidity and mortality. Early recognition, prompt withdrawal of offending agents, and multidisciplinary supportive management are essential for improving clinical outcomes.PMID:38531617 | DOI:10.12809/hkmj2210131 (Source: Hong Kong Medical Journal)
Source: Hong Kong Medical Journal - March 26, 2024 Category: General Medicine Authors: C M T Cheung M M Chang J J X Li A W S Chan Source Type: research

Stevens-Johnson syndrome and toxic epidermal necrolysis in Hong Kong
CONCLUSION: This study showed that SJS/TEN are uncommon in Hong Kong but can cause substantial morbidity and mortality. Early recognition, prompt withdrawal of offending agents, and multidisciplinary supportive management are essential for improving clinical outcomes.PMID:38531617 | DOI:10.12809/hkmj2210131 (Source: Hong Kong Med J)
Source: Hong Kong Med J - March 26, 2024 Category: General Medicine Authors: C M T Cheung M M Chang J J X Li A W S Chan Source Type: research

Stevens-Johnson syndrome and toxic epidermal necrolysis in Hong Kong
CONCLUSION: This study showed that SJS/TEN are uncommon in Hong Kong but can cause substantial morbidity and mortality. Early recognition, prompt withdrawal of offending agents, and multidisciplinary supportive management are essential for improving clinical outcomes.PMID:38531617 | DOI:10.12809/hkmj2210131 (Source: Hong Kong Medical Journal)
Source: Hong Kong Medical Journal - March 26, 2024 Category: General Medicine Authors: C M T Cheung M M Chang J J X Li A W S Chan Source Type: research

Stevens-Johnson syndrome and toxic epidermal necrolysis in Hong Kong
CONCLUSION: This study showed that SJS/TEN are uncommon in Hong Kong but can cause substantial morbidity and mortality. Early recognition, prompt withdrawal of offending agents, and multidisciplinary supportive management are essential for improving clinical outcomes.PMID:38531617 | DOI:10.12809/hkmj2210131 (Source: Hong Kong Med J)
Source: Hong Kong Med J - March 26, 2024 Category: General Medicine Authors: C M T Cheung M M Chang J J X Li A W S Chan Source Type: research