Uric Acid Control in Advanced CKD Uric Acid Control in Advanced CKD
Does conventional allopurinol dosing achieve adequate serum uric acid goals in advanced CKD?Southern Medical Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 12, 2018 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Study: No Link Between Gout Drug, Kidney Disease
Taking the drug allopurinol to manage gout, a painful form of arthritis, is not only safe, but also potentially beneficial in reducing risk of kidney disease, researchers say. (Source: WebMD Health)
Source: WebMD Health - October 8, 2018 Category: Consumer Health News Source Type: news

Gout Drug May Protect Against Chronic Kidney Disease Gout Drug May Protect Against Chronic Kidney Disease
Allopurinol, used to manage gout, was not associated with renal function decline and may protect against development of chronic kidney disease.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 8, 2018 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Study Sees No Link Between Gout Drug, Kidney Disease
MONDAY, Oct. 8, 2018 -- The gout drug allopurinol may offer some protection from kidney disease, according to a new study that upends traditional beliefs. Some doctors hesitate to prescribe the drug to patients because of concerns it may raise... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 8, 2018 Category: General Medicine Source Type: news

Allopurinol Dose Escalation for Gout Doesn't Improve Mortality
THURSDAY, Sept. 20, 2018 -- Allopurinol dose escalation is not associated with reductions in mortality risk among patients with gout, according to a study published in the August issue of Arthritis& Rheumatology. Brian W. Coburn, Ph.D., from... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 20, 2018 Category: Pharmaceuticals Source Type: news

FREED: Febuxostat in Hyperuricemia Shields Kidneys, CV Risk Unclear FREED: Febuxostat in Hyperuricemia Shields Kidneys, CV Risk Unclear
Cardiovascular concerns about the xanthine oxidase inhibitor persist despite reassurances in the trial. Febuxostat's superior uric acid lowering vs allopurinol could work against it, a signal suggests.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 29, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Daily text message may improve adherence and treatment outcomes in patients with gout
(European League Against Rheumatism) The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate significant improvements in adherence and clinical outcomes in gout patients who received a daily text message to remind them to take allopurinol. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 14, 2018 Category: International Medicine & Public Health Source Type: news

Duzallo (Lesinurad and Allopurinol Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 7, 2018 Category: Drugs & Pharmacology Source Type: news

Adding Allopurinol Safe, Effective in IBD (CME/CE)
(MedPage Today) -- Option for those with thiopurine hypermethylation (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 20, 2018 Category: Gastroenterology Source Type: news

Allopurinol: Extra Caution Urged in High-Risk Groups Allopurinol: Extra Caution Urged in High-Risk Groups
The risk for severe cutaneous adverse reactions to allopurinol was much higher among those who were black, Asian, Native Hawaiian/Pacific Islander, women, older, or receiving higher starting doses.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 18, 2018 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Ethnicity Matters in Allopurinol Reactions (CME/CE)
(MedPage Today) -- Blacks, Asians, and Native Hawaiians had greater risk of severe cutaneous reactions than did whites/Hispanics (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 17, 2018 Category: Primary Care Source Type: news

Allopurinol/lesinurad cost effective for gout/hyperuricaemia
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - April 1, 2018 Category: Drugs & Pharmacology Source Type: news

CARES Hints Mortality Risk in CV Patients on Gout Med Febuxostat CARES Hints Mortality Risk in CV Patients on Gout Med Febuxostat
The mortality signal was something of a mystery as a secondary result. Febuxostat was primarily'noninferior'to allopurinol for safety in the patients with a history of cardiovascular disease.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 13, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Does Dose Escalation Help in Gout?
(MedPage Today) -- Given the way allopurinol is used, the question can't really be answered (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 13, 2018 Category: Primary Care Source Type: news

One Gout Medication Comes Out on Top for CV Risk
(MedPage Today) -- Allopurinol the loser in retrospective comparison of two drugs (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 26, 2018 Category: Cardiology Source Type: news

Factors Influencing Allopurinol Initiation in Primary Care Factors Influencing Allopurinol Initiation in Primary Care
Why do only a minority of eligible patients with gout receive timely treatment with allopurinol?Annals of Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 11, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Optimal gout treatment requires ongoing monitoring for urate lowering therapy
(American Academy of Family Physicians) Managing gout as a chronic, rather than an acute, condition could help prevent recurrences. A new study of more than 8,000 medical records found a positive association between starting treatment with allopurinol, a medication that helps prevent gout by lowering production of uric acid, and recurring doctor visits for the condition. Clinicians may therefore be more likely to offer allopurinol, or patients may be more likely to accept it, after multiple acute gout attacks. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2017 Category: International Medicine & Public Health Source Type: news

Gout Drug Febuxostat (Uloric) Subject of FDA Safety Alert Gout Drug Febuxostat (Uloric) Subject of FDA Safety Alert
Preliminary data from a safety study show an increased risk for heart-related deaths with febuxostat compared with allopurinol in patients with gout, the FDA said.News Alerts (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 15, 2017 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news

FDA Drug Safety Communication: FDA to evaluate increased risk of heart-related death and death from all causes with the gout medicine febuxostat (Uloric)
The U.S. Food and Drug Administration (FDA) is warning that preliminary results from a safety clinical trial show an increased risk of heart-related death with febuxostat (Uloric) compared to another gout medicine called allopurinol. We required the Uloric drug manufacturer, Takeda Pharmaceuticals, to conduct this safety study when we approved the medicine in 2009. Once we receive the final results from the manufacturer, we will conduct a comprehensive review and will update the public with any new information. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - November 15, 2017 Category: Drugs & Pharmacology Source Type: news

Allopurinol Decisions Made Early in Primary Care Allopurinol Decisions Made Early in Primary Care
Patients with gout are more likely to receive allopurinol if they meet eligibility criteria for urate-lowering therapy at the time of diagnosis, a study found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 15, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

For Gout, How Safely Can Allopurinol Dosing Be Escalated? For Gout, How Safely Can Allopurinol Dosing Be Escalated?
Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 13, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Duzallo (Lesinurad and Allopurinol Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 31, 2017 Category: Drugs & Pharmacology Source Type: news

Duzallo (allopurinol and lesinurad) for the Treatment of Hyperuricemia Associated with Gout
Duzallo (allopurinol and lesinurad) is indicated for the treatment of hyperuricemia associated with uncontrolled gout. It contains urate transporter-1 (URAT-1) inhibitor blended with xanthine oxidase inhibitor (XOI). (Source: Drug Development Technology)
Source: Drug Development Technology - August 29, 2017 Category: Pharmaceuticals Source Type: news

FDA Approves Duzallo (lesinurad and allopurinol) for Hyperuricemia in Patients with Uncontrolled Gout
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Aug. 21, 2017-- Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) today announced Duzallo was approved by the U.S. Food and Drug Administration (FDA) as a once-daily oral treatment for hyperuricemia associated with... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - August 21, 2017 Category: Drugs & Pharmacology Source Type: news

FDA Clears First Fixed-Dose Combination Treatment for Gout FDA Clears First Fixed-Dose Combination Treatment for Gout
Duzallo combines lesinurad and allopurinol and is indicated for gout-associated hyperuricemia in patients for whom target serum uric acid levels are not achieved with allopurinol alone.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 21, 2017 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news

Gout Patients Run Higher Risk of Kidney Stones (CME/CE)
(MedPage Today) -- 60% increased risk of first-time nephrolithiasis versus general population, with little protection from allopurinol (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - July 31, 2017 Category: Geriatrics Source Type: news

Higher Allopurinol Dose Can Safely Lower SU in Gout (CME/CE)
(MedPage Today) -- Dose escalation even tolerated by patients with CKD (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - April 4, 2017 Category: Consumer Health News Source Type: news

Common yeast may worsen IBD symptoms in Crohn's disease
During the past decade, the gut has experienced a renaissance as investigations focus on the role of the microbiome on human health. While most studies have focused on bacteria, the dominant microbial inhabitants in the gut, scientists used mouse studies to show the role of yeast in aggravating the symptoms of inflammatory bowel disease. Their work suggests that allopurinol, a generic drug already on the market, could offer some relief. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 8, 2017 Category: Science Source Type: news

The Effect of Allopurinol on Renal Function The Effect of Allopurinol on Renal Function
In what ways may treatment with allopurinol impact the kidney?Journal of Clinical Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 1, 2017 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Zyloprim (Allopurinol) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 17, 2017 Category: Drugs & Pharmacology Source Type: news

Ironwood Announces New Drug Application for Duzallo (Fixed-Dose Combination of Lesinurad and Allopurinol) Has Been Accepted for FDA Review
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Jan. 4, 2017-- Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) today announced the U.S. Food and Drug Administration (FDA) accepted for review a New Drug Application (NDA) for Duzallo (fixed-dose combination of... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - January 4, 2017 Category: Drugs & Pharmacology Source Type: news

Aloprim (Allopurinol Sodium for Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 18, 2016 Category: Drugs & Pharmacology Source Type: news

Allopurinol does not increase chronic kidney disease risk in gout patients
(American College of Rheumatology) Allopurinol, a widely used treatment for lowering serum urate levels, does not appear to increase risk of kidney deterioration in gout patients with normal or near-normal kidney function, according to new research findings presented this week at the 2016 ACR/ARHP Annual Meeting in Washington. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 12, 2016 Category: Global & Universal Source Type: news

Lesinurad Succeeds in Gout (CME/CE)
(MedPage Today) -- Serum urate fell to target levels in twice as many patients compared with allopurinol alone (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - August 30, 2016 Category: Primary Care Source Type: news

allopurinol
Title: allopurinol Category: Medications Created: 12/31/1997 12:00:00 AM Last Editorial Review: 7/29/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - July 29, 2016 Category: Rheumatology Source Type: news

Allopurinol Tx Tied to Lower Afib Risk (CME/CE)
(MedPage Today) -- Cohort study suggests cardioprotection from gout drug (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 12, 2016 Category: Cardiology Source Type: news

High-fructose diet during pregnancy may harm placenta, restrict fetal growth
Research in mice and women found that consuming a high-fructose diet during pregnancy may cause defects in the placenta and restrict fetal growth, potentially increasing a baby's risk for metabolic health problems later in life. However, the generic drug allopurinol, frequently prescribed to treat gout and kidney stones, appears to mitigate the negative maternal and fetal effects. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 4, 2016 Category: Science Source Type: news

High-fructose diet during pregnancy may harm placenta, restrict fetal growth
(Washington University in St. Louis) Research in mice and women found that consuming a high-fructose diet during pregnancy may cause defects in the placenta and restrict fetal growth, potentially increasing a baby's risk for metabolic health problems later in life. However, the generic drug allopurinol, frequently prescribed to treat gout and kidney stones, appears to mitigate the negative maternal and fetal effects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 4, 2016 Category: Global & Universal Source Type: news

AstraZeneca Gives U.S. Rights for Gout Drug to Ironwood Pharma
Agreement includes U.S. rights to ZURAMPIC and lesinurad/allopurinol fixed-dose combination in gout (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - April 27, 2016 Category: Pharmaceuticals Source Type: news

Allopurinol Hypersensitivity Higher in Blacks, Asians (CME/CE)
(MedPage Today) -- Severe skin toxicity correlates with carriage of the HLA-B*5801 allele (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - April 15, 2016 Category: Dermatology Source Type: news

Could Coffee Cut the Risk of Gout? (CME/CE)
(MedPage Today) -- It's doubtful that coffee consumption could replace allopurinol (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 29, 2016 Category: Primary Care Source Type: news

New Gout Treatment Effective, Safe in Short Term (CME/CE)
(MedPage Today) -- Lesinurad plus allopurinol significantly increased uric acid clearance (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 12, 2016 Category: Rheumatology Source Type: news

Allopurinol Risky in Asian Population (CME/CE)
(MedPage Today) -- Renal, cardiovascular illness appears to up severe reactions to gout drug. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - July 22, 2015 Category: Cardiology Source Type: news

No Mortality Risk With Allopurinol in Gout (CME/CE)
(MedPage Today) -- An overall neutral effect seen on deaths from all causes. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - July 18, 2015 Category: Primary Care Source Type: news

Allopurinol Treat-to-Target Safe in Gout (CME/CE)
(MedPage Today) -- Adverse event rates low, but only a minority reached uric acid target (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 2, 2015 Category: Primary Care Source Type: news

Allopurinol Industry (Global, China) 2015 Research Analysis and 2020...
DeepResearchReports.com announces new research report "2015 Global and China Allopurinol Industry" added to its store.(PRWeb May 29, 2015)Read the full story at http://www.prweb.com/releases/2015-global-china-allopur/market-research-report/prweb12755089.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - May 30, 2015 Category: Pharmaceuticals Source Type: news

Febuxostat More Effective Than Allopurinol at Usual DosesFebuxostat More Effective Than Allopurinol at Usual Doses
At commonly used doses, febuxostat was more effective than allopurinol at reducing serum uric acid in patients with gout, but allopurinol was likely underdosed. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 27, 2015 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Can Allopurinol Reduce Heart Attack Risk?Can Allopurinol Reduce Heart Attack Risk?
Dr Deane reviews and comments on a recent study looking at the association between use of allopurinol and risk for myocardial infarction. Medscape Rheumatology (Source: Medscape Rheumatology Headlines)
Source: Medscape Rheumatology Headlines - May 21, 2015 Category: Rheumatology Tags: Rheumatology Viewpoint Source Type: news

Impact of Allopurinol on Risk of Myocardial InfarctionImpact of Allopurinol on Risk of Myocardial Infarction
How does allopurinol affect risk for myocardial infarction? Annals of the Rheumatic Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 21, 2015 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Allopurinol Doesn't Worsen Acute Gout Attacks (CME/CE)
(MedPage Today) -- Worries that it might prove unfounded in randomized trial. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - April 10, 2015 Category: Rheumatology Source Type: news