Ironwood Announces New Drug Application for Duzallo (Fixed-Dose Combination of Lesinurad and Allopurinol) Has Been Accepted for FDA Review
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Jan. 4, 2017-- Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) today announced the U.S. Food and Drug Administration (FDA) accepted for review a New Drug Application (NDA) for Duzallo (fixed-dose combination of... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - January 4, 2017 Category: Drugs & Pharmacology Source Type: news
Aloprim (Allopurinol Sodium for Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 18, 2016 Category: Drugs & Pharmacology Source Type: news
Allopurinol does not increase chronic kidney disease risk in gout patients
(American College of Rheumatology) Allopurinol, a widely used treatment for lowering serum urate levels, does not appear to increase risk of kidney deterioration in gout patients with normal or near-normal kidney function, according to new research findings presented this week at the 2016 ACR/ARHP Annual Meeting in Washington. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 12, 2016 Category: Global & Universal Source Type: news
Lesinurad Succeeds in Gout (CME/CE)
(MedPage Today) -- Serum urate fell to target levels in twice as many patients compared with allopurinol alone (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - August 30, 2016 Category: Primary Care Source Type: news
allopurinol
Title: allopurinol < br / > Category: Medications < br / > Created: 12/31/1997 12:00:00 AM < br / > Last Editorial Review: 7/29/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - July 29, 2016 Category: Rheumatology Source Type: news
Allopurinol Tx Tied to Lower Afib Risk (CME/CE)
(MedPage Today) -- Cohort study suggests cardioprotection from gout drug (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - May 12, 2016 Category: Cardiology Source Type: news
High-fructose diet during pregnancy may harm placenta, restrict fetal growth
Research in mice and women found that consuming a high-fructose diet during pregnancy may cause defects in the placenta and restrict fetal growth, potentially increasing a baby's risk for metabolic health problems later in life. However, the generic drug allopurinol, frequently prescribed to treat gout and kidney stones, appears to mitigate the negative maternal and fetal effects. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 4, 2016 Category: Science Source Type: news
High-fructose diet during pregnancy may harm placenta, restrict fetal growth
(Washington University in St. Louis) Research in mice and women found that consuming a high-fructose diet during pregnancy may cause defects in the placenta and restrict fetal growth, potentially increasing a baby's risk for metabolic health problems later in life. However, the generic drug allopurinol, frequently prescribed to treat gout and kidney stones, appears to mitigate the negative maternal and fetal effects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 4, 2016 Category: Global & Universal Source Type: news
AstraZeneca Gives U.S. Rights for Gout Drug to Ironwood Pharma
Agreement includes U.S. rights to ZURAMPIC and lesinurad/allopurinol fixed-dose combination in gout (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - April 27, 2016 Category: Pharmaceuticals Source Type: news
Allopurinol Hypersensitivity Higher in Blacks, Asians (CME/CE)
(MedPage Today) -- Severe skin toxicity correlates with carriage of the HLA-B*5801 allele (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - April 15, 2016 Category: Dermatology Source Type: news
Could Coffee Cut the Risk of Gout? (CME/CE)
(MedPage Today) -- It's doubtful that coffee consumption could replace allopurinol (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - January 29, 2016 Category: Primary Care Source Type: news
New Gout Treatment Effective, Safe in Short Term (CME/CE)
(MedPage Today) -- Lesinurad plus allopurinol significantly increased uric acid clearance (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 12, 2016 Category: Rheumatology Source Type: news
Allopurinol Risky in Asian Population (CME/CE)
(MedPage Today) -- Renal, cardiovascular illness appears to up severe reactions to gout drug. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - July 22, 2015 Category: Cardiology Source Type: news
No Mortality Risk With Allopurinol in Gout (CME/CE)
(MedPage Today) -- An overall neutral effect seen on deaths from all causes. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - July 18, 2015 Category: Primary Care Source Type: news
Allopurinol Treat-to-Target Safe in Gout (CME/CE)
(MedPage Today) -- Adverse event rates low, but only a minority reached uric acid target (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 2, 2015 Category: Primary Care Source Type: news
