Factors Influencing Allopurinol Initiation in Primary Care Factors Influencing Allopurinol Initiation in Primary Care
Why do only a minority of eligible patients with gout receive timely treatment with allopurinol?Annals of Family Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 11, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Optimal gout treatment requires ongoing monitoring for urate lowering therapy
(American Academy of Family Physicians) Managing gout as a chronic, rather than an acute, condition could help prevent recurrences. A new study of more than 8,000 medical records found a positive association between starting treatment with allopurinol, a medication that helps prevent gout by lowering production of uric acid, and recurring doctor visits for the condition. Clinicians may therefore be more likely to offer allopurinol, or patients may be more likely to accept it, after multiple acute gout attacks. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2017 Category: International Medicine & Public Health Source Type: news

Gout Drug Febuxostat (Uloric) Subject of FDA Safety Alert Gout Drug Febuxostat (Uloric) Subject of FDA Safety Alert
Preliminary data from a safety study show an increased risk for heart-related deaths with febuxostat compared with allopurinol in patients with gout, the FDA said.News Alerts (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 15, 2017 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news

FDA Drug Safety Communication: FDA to evaluate increased risk of heart-related death and death from all causes with the gout medicine febuxostat (Uloric)
The U.S. Food and Drug Administration (FDA) is warning that preliminary results from a safety clinical trial show an increased risk of heart-related death with febuxostat (Uloric) compared to another gout medicine called allopurinol. We required the Uloric drug manufacturer, Takeda Pharmaceuticals, to conduct this safety study when we approved the medicine in 2009. Once we receive the final results from the manufacturer, we will conduct a comprehensive review and will update the public with any new information. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - November 15, 2017 Category: Drugs & Pharmacology Source Type: news

Allopurinol Decisions Made Early in Primary Care Allopurinol Decisions Made Early in Primary Care
Patients with gout are more likely to receive allopurinol if they meet eligibility criteria for urate-lowering therapy at the time of diagnosis, a study found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 15, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

For Gout, How Safely Can Allopurinol Dosing Be Escalated? For Gout, How Safely Can Allopurinol Dosing Be Escalated?
Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 13, 2017 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Duzallo (Lesinurad and Allopurinol Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 31, 2017 Category: Drugs & Pharmacology Source Type: news

Duzallo (allopurinol and lesinurad) for the Treatment of Hyperuricemia Associated with Gout
Duzallo (allopurinol and lesinurad) is indicated for the treatment of hyperuricemia associated with uncontrolled gout. It contains urate transporter-1 (URAT-1) inhibitor blended with xanthine oxidase inhibitor (XOI). (Source: Drug Development Technology)
Source: Drug Development Technology - August 29, 2017 Category: Pharmaceuticals Source Type: news

FDA Approves Duzallo (lesinurad and allopurinol) for Hyperuricemia in Patients with Uncontrolled Gout
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Aug. 21, 2017-- Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) today announced Duzallo was approved by the U.S. Food and Drug Administration (FDA) as a once-daily oral treatment for hyperuricemia associated with... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - August 21, 2017 Category: Drugs & Pharmacology Source Type: news

FDA Clears First Fixed-Dose Combination Treatment for Gout FDA Clears First Fixed-Dose Combination Treatment for Gout
Duzallo combines lesinurad and allopurinol and is indicated for gout-associated hyperuricemia in patients for whom target serum uric acid levels are not achieved with allopurinol alone.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 21, 2017 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news

Gout Patients Run Higher Risk of Kidney Stones (CME/CE)
(MedPage Today) -- 60% increased risk of first-time nephrolithiasis versus general population, with little protection from allopurinol (Source: MedPage Today Geriatrics)
Source: MedPage Today Geriatrics - July 31, 2017 Category: Geriatrics Source Type: news

Higher Allopurinol Dose Can Safely Lower SU in Gout (CME/CE)
(MedPage Today) -- Dose escalation even tolerated by patients with CKD (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - April 4, 2017 Category: Consumer Health News Source Type: news

Common yeast may worsen IBD symptoms in Crohn's disease
During the past decade, the gut has experienced a renaissance as investigations focus on the role of the microbiome on human health. While most studies have focused on bacteria, the dominant microbial inhabitants in the gut, scientists used mouse studies to show the role of yeast in aggravating the symptoms of inflammatory bowel disease. Their work suggests that allopurinol, a generic drug already on the market, could offer some relief. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 8, 2017 Category: Science Source Type: news

The Effect of Allopurinol on Renal Function The Effect of Allopurinol on Renal Function
In what ways may treatment with allopurinol impact the kidney?Journal of Clinical Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 1, 2017 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Zyloprim (Allopurinol) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 17, 2017 Category: Drugs & Pharmacology Source Type: news