Similarities and Distinctions Between Acetazolamide and SGLT2 Inhibitors in Patients With Acute Heart Failure: Key Insights Into ADVOR and EMPULSE
This article is protected by copyright. All rights reserved. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - July 5, 2023 Category: Cardiology Authors: Milton Packer,
Javed Butler Tags: Review Article Source Type: research
White Matter Cerebrovascular Reactivity: Effects of Microangiopathy and Proximal Occlusions on the Dynamic BOLD Response
CONCLUSION: Our results suggest additive effects of microvascular and macrovascular disease upon white matter CVR, but with greater overall effects relating to macrovascular SOD than to apparent microangiopathy. Dynamic ACZ-BOLD presents a promising path towards a quantitative stroke risk imaging biomarker.BACKGROUND: Cerebral white matter (WM) microangiopathy manifests as sporadic or sometimes confluent high intensity lesions in MR imaging with T2-weighting, and bears known associations with stroke, cognitive disability, depression and other neurological disorders 1-5 . Deep white matter is particularly susceptible to isc...
Source: Atherosclerosis - July 3, 2023 Category: Cardiology Authors: J Michael Gee Xiuyuan Wang Siddhant Dogra Jelle Veraart Koto Ishida Seena Dehkharghani Source Type: research
White Matter Cerebrovascular Reactivity: Effects of Microangiopathy and Proximal Occlusions on the Dynamic BOLD Response
CONCLUSION: Our results suggest additive effects of microvascular and macrovascular disease upon white matter CVR, but with greater overall effects relating to macrovascular SOD than to apparent microangiopathy. Dynamic ACZ-BOLD presents a promising path towards a quantitative stroke risk imaging biomarker.BACKGROUND: Cerebral white matter (WM) microangiopathy manifests as sporadic or sometimes confluent high intensity lesions in MR imaging with T2-weighting, and bears known associations with stroke, cognitive disability, depression and other neurological disorders 1-5 . Deep white matter is particularly susceptible to isc...
Source: Atherosclerosis - July 3, 2023 Category: Cardiology Authors: J Michael Gee Xiuyuan Wang Siddhant Dogra Jelle Veraart Koto Ishida Seena Dehkharghani Source Type: research
Safety and Efficacy of Oral Acetazolamide Therapy in Relief of Congestion in Patients With Heart Failure and Diuretic Resistance
This study sought to assess the safety and efficacy of ACZ in HF patients with diuretic resistance. (Source: Heart, Lung and Circulation)
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: D. Chan, A. Chai, H. Chen, S. Khanna, E. Ho, K. Gu, A. Latumahina, S. Hales, A. Sindone, G. Gan Source Type: research
Intravitreal acetazolamide implant for pseudophakic cystoid macular edema
ConclusionWe show that PCME refractory to conventional treatment improved after intravitreal acetazolamide implant injection. Further investigation is warranted to confirm these preliminary findings. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - June 28, 2023 Category: Opthalmology Source Type: research
Acetazolamide responsive early-onset absence epilepsy and ataxia in a toddler with a KCNA2 genetic variant; a case report
Genetic variants in KCNA2 (potassium voltage-gated channel subfamily A member 2) have been associated with a spectrum of symptoms such as epileptic encephalopathy, myoclonic seizures, intellectual disability, and cerebellar ataxia [1,2]. Individuals with KCNA2 gain-of-function genetic variants could benefit from tailored-treatment regimens [1,3]. Here, we report a 2-year-old boy with early-onset drug refractory absence seizures and gait ataxia. The clinical exome sequencing revealed a gain-of-function genetic variant in the KCNA2 gene. (Source: Seizure: European Journal of Epilepsy)
Source: Seizure: European Journal of Epilepsy - June 18, 2023 Category: Neurology Authors: Neetha Balaram, James Jose, Abdul Gafoor, Smita Balachandran, Francis Saritha, Kalarickal Vijayan Dileep, Shabeesh Balan Source Type: research
Acetazolamide as a Decongestion Strategy in Acute Decompensated Heart Failure: Balancing Fluid Removal and Electrolyte Disturbances
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - June 16, 2023 Category: Cardiology Authors: Zara Butte,
Andrew P. Ambrosy Tags: Invited Editorial Source Type: research
ASL-MRI-guided evaluation of multiple burr hole revascularization surgery in Moyamoya disease
ConclusionUsing ASL-MRI we followed changes in CBF and CVR in patients with MM. The technique was encouraging for assessments before and after revascularization surgery. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - June 16, 2023 Category: Neurosurgery Source Type: research
