Clinical course of two siblings with potassium voltage-gated channel modifier subfamily V member 2 (KCNV2)-associated retinopathy
ConclusionsThe siblings had clinical findings typical of CDSRR. High-intense flash ERG is recommended for identifying pathognomonic “squaring” a-waves in patients with CDSRR. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - April 17, 2024 Category: Opthalmology Source Type: research

Optic nerve involvement in patients with Lyme neuroborreliosis: an electrophysiological study
ConclusionIn LNB patients, VEP helps to increase sensitivity of an early diagnostic process. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - April 15, 2024 Category: Opthalmology Source Type: research

Questioning accelerated hydroxychloroquine retinopathy
(Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - April 13, 2024 Category: Opthalmology Source Type: research

Slope between positive and negative ERG components in patients with open-angle glaucoma
ConclusionsThe P50-N95 slope is a sensitive indicator of RGC dysfunction in patients with open-angle glaucoma. A similar component of LA-ERG, the b-PhNR slope, is less affected by glaucomatous RGC dysfunction and probably originates from similar retinal mechanisms as the b-wave. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - April 12, 2024 Category: Opthalmology Source Type: research

Accelerated hydroxychloroquine toxic retinopathy (response to letter)
(Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - April 5, 2024 Category: Opthalmology Source Type: research

Morphological and Functional Correlations in Acute Central Serous Chorioretinopathy
ConclusionsSRF and CRT could serve as the most representative morphological proxies for visual function deficit in acute CSC patients. Retinal sensitivity, as measured by MP, may be superior to BCVA in clinical research studies or when an in-depth visual function evaluation is needed. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - March 18, 2024 Category: Opthalmology Source Type: research

ISCEV standard for clinical pattern electroretinography (2024 update)
AbstractThe pattern electroretinogram (PERG) is a localized retinal response evoked by a contrast-reversing pattern, usually a black and white checkerboard, which provides information about macular and retinal ganglion cell function. This document, from the International Society for Clinical Electrophysiology of Vision (ISCEV;www.iscev.org) presents an updated and revised Standard for clinical PERG testing. This replaces the 2013 and all earlier versions. Minimum protocols for basic PERG stimuli, recording methods and reporting are specified, to promote consistency of methods for diagnosis and monitoring purposes, while re...
Source: Documenta Ophthalmologica - March 15, 2024 Category: Opthalmology Source Type: research

Electroretinographic oscillatory potentials in Leber hereditary optic neuropathy
ConclusionsReduced OPs in LHON patients may represent disturbed neuronal interactions in the inner retina with preserved photoreceptoral (a-wave) to bipolar cell (b-wave) activation. Reduced DA OP2 and high-cutoff LA OP alterations may be further explored as functional measures to characterize LHON status and progression. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - March 7, 2024 Category: Opthalmology Source Type: research

Effect of eccentric fixation on the steady-state pattern electroretinogram
ConclusionGenerally, moderate inaccuracies of fixation do not have a sizable effect on ssPERG amplitude. However, with large checks, the luminance response has to be considered. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - February 28, 2024 Category: Opthalmology Source Type: research

Autoimmune retinopathy in a patient with smoldering multiple myeloma: a case report
ConclusionThe association of autoimmune retinopathy with multiple myeloma is rare. It is crucial for physicians to be aware of such manifestations to ensure timely and appropriate diagnosis and management for patients. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - February 16, 2024 Category: Opthalmology Source Type: research

The IPS and ISCEV joint guidelines for full-field stimulus testing
(Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - February 14, 2024 Category: Opthalmology Source Type: research

Videoocular assessment of eye movement activity in an ataxia –telangiectasia: a case study
ConclusionOur study opens the prospect to evaluate efficacy and safety of alternative methods for supporting the patient and improving his/her life quality. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - February 14, 2024 Category: Opthalmology Source Type: research

Case of persistent corneal epithelial damage after cataract surgery leading to diagnosis of vitamin A deficiency
ConclusionOur findings indicate that the ERGs are helpful for diagnosing patients with VAD associated with persistent corneal epithelial damages. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - January 24, 2024 Category: Opthalmology Source Type: research

Sensitivity and specificity of the uniform field electroretinogram in glaucoma detection in comparison to the pattern electroretinogram
ConclusionsPERG bar stimuli and the PhNR of the UF-ERG can be used in the clinical setting to detect glaucoma-related changes in glaucoma-suspect and glaucoma patients. However, our data confirm that the PhNR peak time has the best combined sensitivity and specificity. (Source: Documenta Ophthalmologica)
Source: Documenta Ophthalmologica - January 20, 2024 Category: Opthalmology Source Type: research

ISCEV and IPS guideline for the full-field stimulus test (FST)
AbstractThe full-field stimulus test (FST) is a psychophysical technique designed for the measurement of visual function in low vision. The method involves the use of a ganzfeld stimulator, as used in routine full-field electroretinography, to deliver full-field flashes of light. This guideline was developed jointly by the International Society for Clinical Electrophysiology of Vision (ISCEV) and Imaging and Perimetry Society (IPS) in order to provide technical information, promote consistency of testing and reporting, and encourage convergence of methods for FST. It is intended to aid practitioners and guide the formulati...
Source: Documenta Ophthalmologica - January 18, 2024 Category: Opthalmology Source Type: research