A High-Cholesterol Diet Increases Toll-like Receptors and Other Harmful Factors in the Rabbit Myocardium: The Beneficial Effect of Statins

CONCLUSIONS: HCD increases the levels of TLRs; inflammatory, fibrotic and apoptotic factors; and BNP in the rabbit myocardium. Atherogenic diets adversely affect the myocardium at a molecular level and are reversed by statins.PMID:34449561 | DOI:10.3390/cimb43020059

Source: Current Issues in Molecular Biology - August 27, 2021 Category: Molecular Biology Authors: Alkistis Kapelouzou Michalis Katsimpoulas Christos Kontogiannis Irene Lidoriki Georgios Georgiopoulos Christos Kourek Christos Papageorgiou Konstantinos S Mylonas Spyridon Dritsas Alexandros Charalabopoulos Dennis V Cokkinos Source Type: research