P057  What is the course of SARS-CoV-2 infection in people with autoimmune conditions on immunomodulators in comparison to people without autoimmune disease?

Conclusion People with and without autoimmune disease presented with similar symptoms of COVID-19. In our sample, subjects with autoimmune disease were less likely to be hospitalised or require respiratory support. Serology revealed no difference in antibody titres against SARS-CoV-2 in participants with an d without autoimmune disease. P057 Table 1:A comparison of the clinical features of COVID-19 in patients with and without autoimmune diseaseParticipants with autoimmune disease (n = 26)Participants without autoimmune disease (n = 26)Average age5855Male to female ratio10:1610:16EthnicityWhite 50%Black 23%Asian 27%White 62%Black 12%Asian 15%Other 4%Co-morbiditiesHypertension 35%Diabetes 19%Obstructive lung disease 12%Interstitial lung disease 12%Ischaemic heart disease 4%Hypertension 23%Diabetes 20%Obstructive lung disease 15%Interstitial lung disease 0%Ischaemic heart disease 12%Most common symptoms of COVID-19 infectionMalaise 73%Cough 73%Fever 70%Dyspnoea 62%Malaise 84%Cough 85%Fever 77%Dyspnoea 65%Level of care required during acute illnessHome 39%Ward 57%Intensive Care Unit 4%Home 27%Ward 58%High Dependency Unit 15%Respiratory supportNone 65%Oxygen therapy 30%Non-invasive ventilation 0%Invasive ventilation 5%None 46%Oxygen therapy 38%Non-invasive ventilation 15%Invasive ventilation 0%Disclosure K. Biddle: None.S. Koushesh: None.D. Clark: None.S. Krishna: None.S. Webb: None.K. Patel: None.R. Pollok: None.N. Sofat: None.
Source: Rheumatology - Category: Rheumatology Source Type: research