Vitamin D supplementation for sickle cell disease.

CONCLUSIONS: We included three RCTs of varying quality. We consider that the current evidence presented in this review is not of sufficient quality to guide clinical practice. Until further evidence becomes available, clinicians should consider the relevant existing guidelines for vitamin D supplementation and dietary reference intakes for calcium and vitamin D. Well-designed RCTs of parallel design, are required to determine the effects and the safety of vitamin D supplementation as well as to assess the relative benefits of different doses in children and adults with SCD.
PMID: 32462740 [PubMed - in process]

Source: Cochrane Database of Systematic Reviews - May 27, 2020 Category: General Medicine Authors: Soe HHK, Abas AB, Than NN, Ni H, Singh J, Said ARBM, Osunkwo I Tags: Cochrane Database Syst Rev Source Type: research