Weight gain, but not macronutrient intake, modifies the effect of dietary Branch chain amino acids on the risk of metabolic syndrome

Metabolic syndrome (MetS) is a pathologic condition that encompasses dyslipidaemia, abdominal obesity, insulin resistance, and hypertension [1] and is strongly linked to increasing incidence of chronic diseases, including type 2 diabetes, cancer, cardiovascular disease, chronic kidney disease and chronic obstructive pulmonary disease [2 –4]. The global epidemic of MetS underscores the vital need for more attention to be paid to the prevention and treatment MetS by controlling lifestyles and environmental factors such as manipulation of macro- and micronutrients in dietary patterns, including branch chain amino acids (BCAAs) [5,6] , a group of essential amino acids associated with metabolic disease which predict the progress of type 2 diabetes [7–9].
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research