A novel mouse model of acute-on-chronic cholestatic alcoholic liver disease: A systems biology comparison with human alcoholic hepatitis.

CONCLUSIONS: We developed a novel mouse model of acute-on chronic cholestatic alcoholic liver injury that has considerable translational potential and can be used to test novel therapeutic modalities for AH.
PMID: 31710124 [PubMed - as supplied by publisher]

Source: Alcoholism, Clinical and Experimental Research - November 9, 2019 Category: Addiction Authors: Furuya S, Argemi J, Uehara T, Katou Y, Fouts DE, Schnabl B, Dubuquoy L, Belorkar A, Vadigepalli R, Kono H, Bataller R, Rusyn I Tags: Alcohol Clin Exp Res Source Type: research