Cancers, Vol. 11, Pages 1782: A Review on Curability of Cancers: More Efforts for Novel Therapeutic Options Are Needed

Cancers, Vol. 11, Pages 1782: A Review on Curability of Cancers: More Efforts for Novel Therapeutic Options Are Needed Cancers doi: 10.3390/cancers11111782 Authors: Shuncong Wang Yewei Liu Yuanbo Feng Jian Zhang Johan Swinnen Yue Li Yicheng Ni Cancer remains a major cause of death globally. Given its relapsing and fatal features, curing cancer seems to be something hardly possible for the majority of patients. In view of the development in cancer therapies, this article summarizes currently available cancer therapeutics and cure potential by cancer type and stage at diagnosis, based on literature and database reviews. Currently common cancer therapeutics include surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy. However, treatment with curative intent by these methods are mainly eligible for patients with localized disease or treatment-sensitive cancers and therefore their contributions to cancer curability are relatively limited. The prognosis for cancer patients varies among different cancer types with a five-year relative survival rate (RSR) of more than 80% in thyroid cancer, melanoma, breast cancer, and Hodgkin’s lymphoma. The most dismal prognosis is observed in patients with small-cell lung cancer, pancreatic cancer, hepatocellular carcinoma, oesophagal cancer, acute myeloid leukemia, non-small cell lung cancer, and gastric cancer with a five-year RSR ranging between 7% and 28%. The current review is intended to ...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research