Risk for Psychiatric Disorders, Suicide Higher in Children With IBD

Children with inflammatory bowel disease (IBD) may be at higher risk for psychiatric disorders and suicide attempt, according to a large, population-basedstudy published inJAMA Pediatrics.The risk for psychiatric disorders and suicide among children with IBD was greater when compared with siblings without IBD, indicating that the risk is likely related to IBD itself and not to genetic or environmental factors shared with siblings."Particularly concerning is the increased risk of suicide attempt," wrote Agnieszka Butwicka, M.D., Ph.D., of the Karolinska Institute in Sweden and colleagues. "Long-term psychological support should therefore be considered for patients with childhood-onset IBD."The study included all children born in Sweden between 1973 and 2013. Researchers compared those who were diagnosed with ulcerative colitis (n=3,228), Crohn's disease (n=2,536), or IBD-unclassified (n=700) before age 18 with 323,200 matched controls and 6,999 siblings without IBD. The average age at diagnosis of IBD was 14.The primary outcome was any psychiatric disorder and suicide attempt during a median follow up of nine years. Secondary outcomes were diagnoses of specific disorders including psychotic, mood, anxiety, eating, and personality disorders as well as substance use, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, and intellectual disability.The risk of any psychiatric disorder was increased in all IBD subgroups, with a hazard ratio (HR) of 1.6. This i...
Source: Psychiatr News - Category: Psychiatry Tags: ADHD anxiety autism Crohn's disease IBD inflammatory bowel disease mood disorders personality disorders suicide ulcerative colitis Source Type: research