Non-alcoholic fatty liver disease: A growing public health problem in Turkey.

Non-alcoholic fatty liver disease: A growing public health problem in Turkey. Turk J Gastroenterol. 2019 Jul 01;: Authors: Kaya E, Yılmaz Y Abstract Non-alcoholic fatty liver disease (NAFLD) is histologically classified as either non-alcoholic fatty liver or non-alcoholic steatohepatitis (NASH). NASH is the progressive subtype of NAFLD. Individuals with NASH are at significant risk of developing hepatic fibrosis, cirrhosis, hepatocellular carcinoma, and liver-related and all-cause mortality. NAFLD is closely associated with obesity, type 2 diabetes mellitus (T2DM), metabolic syndrome, and cardiovascular events. Its prevalence is estimated to be above 30% in Turkey; and recent studies confirm this estimate. According to these studies, the prevalence of NAFLD in Turkey is between 48.3% and 60.1%. Currently, Turkey can be considered a risky region in terms of NAFLD burden as it is the most obese country in Europe with an obesity prevalence of 32.1% according to the 2016 World Health Organization data. Moreover, along with the increasing prevalence of obesity and T2DM in Turkey, the burden of NAFLD is estimated to increase in the upcoming decade. Despite the growing burden, we lack well-designed systemic studies that investigate NAFLD and its marked histological severity. In this review, we present studies on the burden of NAFLD and NASH, the natural history of NAFLD, and its association with other systemic diseases conducted with Turkish populations. ...
Source: The Turkish Journal of Gastroenterology - Category: Gastroenterology Authors: Tags: Turk J Gastroenterol Source Type: research

Related Links:

Authors: Mascitti M, Togni L, Rubini C, Troiano G, Lo Muzio L, Santarelli A Abstract Oral squamous cell carcinoma is the most common head and neck malignancy, characterised by high invasive capacity, lymph node metastasis, and high recurrence rate. Among the morphological features of oral cancer, the tumour-associated tissue eosinophilia has gained growing interest in the last years. Eosinophils are a minor subpopulation of leukocytes, representing 1-3% of all circulating white blood cells. The presence of high levels of eosinophils is associated with several diseases, but their role in cancer pathophysiology is co...
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
Abatacept relieves kidney injury in diabetic nephropathy rats by inhibiting TGF-β1/SMAD7 signaling pathway. J Biol Regul Homeost Agents. 2020 Sep 29;34(5): Authors: Ye L, Pan YY, Jin FH, Zhang DH, Xu QL, Zhang L PMID: 32989981 [PubMed - as supplied by publisher]
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
Publication date: Available online 30 September 2020Source: Journal of the American Society of CytopathologyAuthor(s): Stacey M. Gargano, Christopher Sebastiano, Jack Mardekian, Charalambos C. Solomides, Kim HooKim
Source: Journal of the American Society of Cytopathology - Category: Cytology Source Type: research
Publication date: 29 September 2020Source: Cell Reports, Volume 32, Issue 13Author(s): Xiao Wei, Zongshi Lu, Li Li, Hexuan Zhang, Fang Sun, Huan Ma, Lijuan Wang, Yingru Hu, Zhencheng Yan, Hongting Zheng, Gangyi Yang, Daoyan Liu, Martin Tepel, Peng Gao, Zhiming Zhu
Source: Cell Reports - Category: Cytology Source Type: research
CONCLUSION: Paying more attention to food insecurity and to the affordability of vegetables are avenues to explore in view of improving the quality of nourishment in Canada. In any event, longitudinal studies shall be required to confirm the role and to measure the actual influence of these variables on the quality of individual adult diets. PMID: 32981771 [PubMed - as supplied by publisher]
Source: Revue d Epidemiologie et de Sante Publique - Category: Epidemiology Tags: Rev Epidemiol Sante Publique Source Type: research
Publication date: Available online 30 September 2020Source: Obesity Research &Clinical PracticeAuthor(s): Guilherme Dienstmann, Iramar Baptistella do Nascimento, Willian Barbosa Sales, Matheus Leite Ramos de Souza, Grazielle Dutra da Silva, Larissa Cano de Oliveira, Jean Carl Silva
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
Non-alcoholic fatty liver disease (NAFLD) comprises fatty liver (steatosis), non-alcoholic steatohepatitis (NASH) and fibrosis/cirrhosis and may lead to end-stage liver failure or hepatocellular carcinoma. NAFLD is tightly associated with the most frequent metabolic disorders, such as obesity, metabolic syndrome, and type 2 diabetes mellitus (T2DM). Both multisystem diseases share several common mechanisms. Alterations of tissue communications include excessive lipid and later cytokine release by dysfunctional adipose tissue, intestinal dysbiosis and ectopic fat deposition in skeletal muscle.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Source Type: research
Abstract Non-alcoholic fatty liver disease (NAFLD) is one of the most common comorbidities associated with overweight and metabolic syndrome (MetS). Importantly, NAFLD is one of its most dangerous complications because it can lead to severe liver pathologies, including fibrosis, cirrhosis and hepatic cellular carcinoma. Given the increasing worldwide prevalence of obesity, NAFLD has become the most common cause of chronic liver disease and therefore is a major global health problem. Currently, NAFLD is predominantly regarded as a hepatic manifestation of MetS. However, accumulating evidence indicates that the effe...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
Publication date: Available online 11 June 2015 Source:Progress in Lipid Research Author(s): Tigyi Joost Willebrords , Isabel Veloso Alves Pereira , Michaël Maes , Sara Crespo Yanguas , Isabelle Colle , Bert Van Den Bossche , Tereza Cristina Da silva , Cláudia Oliveira , Wellington Andraus , Mathieu Vinken Non-alcoholic fatty liver disease encompasses a spectrum of liver diseases, including simple steatosis, steatohepatitis, liver fibrosis and cirrhosis and hepatocellular carcinoma. Non-alcoholic fatty liver disease is currently the most dominant chronic liver disease in Western countries due to the fact that...
Source: Progress in Lipid Research - Category: Lipidology Source Type: research
Abstract Non-alcoholic liver disease (NAFLD) defines liver abnormalities ranging from simple steatosis to nonalcoholic steatohepatitis with or without cirrhosis development, occurring in the absence of significant alcohol consumption, use of teratogenic medication, or hereditary disorders. The association between NAFLD and metabolic syndrome is well documented and widely recognized. Obesity, type 2 diabetes mellitus (T2DM), and dyslipidemia are the most common metabolic risk factors associated with NAFLD. Among the components of metabolic syndrome, current evidence strongly indicates obesity and diabetes as hepato...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
More News: Alcoholism | Cancer & Oncology | Carcinoma | Cardiology | Cardiovascular | Cirrhosis | Diabetes | Diabetes Mellitus | Diabetes Type 2 | Eating Disorders & Weight Management | Endocrinology | Fatty Liver Disease (FLD) | Gastroenterology | Heart | Hepatocellular Carcinoma | International Medicine & Public Health | Liver | Liver Cancer | Liver Disease | Metabolic Syndrome | Middle East Health | Non-alcoholic Fatty Liver Diseases (NAFLD) | Obesity | Study | Turkey Health | Urology & Nephrology | WHO