Clinical profile of tuberculosis in patients with chronic kidney disease: A report from an endemic Country.

The objective is to study the clinical profile of tuberculosis (TB) in chronic kidney disease (CKD). This is retrospective study of CKD patients who were diagnosed to have TB over a period of seven years at a tertiary care hospital. TB was diagnosed in 115 patients with an incidence of 4200/100,000. Mean age of the patients was 46.9 ± 16 years. Sixty-two patients (53.9%) were male. Causes of CKD were diabetic nephropathy and hypertension in 11.3% each, chronic glomerulonephritis in 31.3%, chronic tubulointerstitial nephritis in 39.1%, autosomal dominant polycystic kidney disease, and post-renal transplant CKD in 3.5% each. About 68.7% of patients with TB had advanced CKD stage of 4-5D, whereas 31.3% of patients had early CKD stage 1-3. Twenty percent of patients were on dialysis. Three-fourths of the patients had extrapulmonary TB. Pleuropulmonary (41.8%), kidney and urinary tract (20%), and abdomen and lymph node (13% each) were the most common sites for TB. The main clinical presentation of TB was: fever/pyrexia of unknown origin in 24.3%, constitutional symptoms of anorexia, fever, night sweats, and weight loss in 27.8%, abnormal chest radiograph in 31.2%, ascites/peritonitis in 13.9%, pleural effusion in 25.2%, lymphadenopathy in 20%, and sterile pyuria/hematuria/chronic pyelonephritis in 13%. Microbiological and/or histopathological diagnoses were made in 45.2% and in the other 54.8%, diagnosis of TB was made on clinical grounds. Adverse effects of anti-TB drugs w...
Source: Saudi Journal of Kidney Diseases and Transplantation - Category: Urology & Nephrology Authors: Tags: Saudi J Kidney Dis Transpl Source Type: research

Related Links:

Authors: Kruthiventi SC, Kane GC, Sprung J, Weingarten TN, Warner ME Abstract Patients with pulmonary hypertension are at increased risk for postoperative pulmonary complications (PPCs). Herein, we review PPCs in pulmonary hypertension patients undergoing non-cardiac procedures under general anesthesia. The medical records of pulmonary hypertension patients who underwent surgery with general anesthesia between 2010 and 2017 were reviewed for PPCs. In addition we reviewed nursing-documented respiratory depressive episodes in the post-anesthesia care unit to assess the associations between these episodes and later PP...
Source: Bosnian Journal of Basic Medical Sciences - Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research
We report a clinical case of DRESS syndrome with liver injury, evaluated with the RegiSCAR scoring system as a "definite case" possibly induced by carbamazepine in a patient. PMID: 31299851 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Fatima J, Gupta N, Karoli R, Chandra A, Jagirdaar S, Arora R, Pandey N Abstract Introduction: Visceral abdominal Fat, not Subcutaneous Abdominal Fat better correlates with insulin resistance. Hence the present study was undertaken to study the association of sonographically assessed visceral and subcutaneous abdominal fat with insulin resistance in patients with pre-diabetes. Material and Methods: It was a hospital based cross sectional study done in prediabetes subjects. All the subjects were called fasting overnight and were given a structured questionnaire designed by investigator. Fasting and postp...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: S A, Gurtoo A, M S, Ap MK Abstract Introduction: Health literacy is the degree to which an individual can obtain, process, understand and communicate about health related information to make informed health decisions. Our aim was to study the influence of Diabetic health literacy in affecting the glycemic control in Diabetic patients. Methodology: This is a Cross sectional Analytical study in 200 diabetic patients. Diabetic Knowledge Test developed by Michigan Diabetic Research and Training Center was modified after appropriate permission and was used to measure health literacy. HbA1C was used as a mea...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusions: We concluded that that patients who develop hypoglycaemia may have an equally bad prognosis or even worse than those who develop hyperglycaemia during the period of critical illness. CGM devices record tissue glucose levels continuously, and may be useful as a 'tissue hypoglycaemia' alert. PMID: 31299838 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: There is a need to focus on improving adherence among type 2 diabetes patients and strengthening health care systems for regular supply of medicines and provide health education to the patients and their families emphasising the need of adherence to medications. PMID: 31299834 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Khairnar H, Ingle M, Chauhan S, Pipalia N, Sawant P, Pandey V, Shukla A Abstract Introduction: Computed Tomography of abdomen frequently shows bowel wall thickening with different grades and characteristic of thickening. The correlation of bowel wall thickening (BWT) with endoscopic findings is not well described in Indian population. Therefore we did this study to determine the correlation of BWT with endoscopic findings. Methods: Its Prospective single center study with 85 Consecutive patients with age group more than 12 years with CT scan abdomen showing bowel wall thickening were included in the st...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusions: Overall, Periventricular WMHs of grade 2 and over were seen in 19/34 patients, and in 7/24 controls (P value 0.044). Significantly higher grades of PVWMHs were seen in hypertensives as compared to nonhypertensives in the case group, and in women compared to men. In the control group, hypertension had no effect on severity of PVWMHs. Among both Diabetics and non-diabetics, no difference in PVWMHs was found between the case and control groups. DWMHs were, conversely, seen only in the control group. Overall, over a quarter of cognitively normal older persons had WM hyperintensities of grade 2 and over on MRI brai...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
UPMC began its transplant program in 1981 and has, since then, performed 20,000.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
ConclusionThe regulatory pathway of axon regeneration involving nerve growth related factors and low intensity pulsed ultrasound was initially established, which provided a theoretical basis for further study of axon regeneration, and also new ideas for action of low intensity pulsed ultrasound on axon regeneration regulatory pathway.
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
More News: Anorexia | Chronic Kidney Disease | Diabetes | Dialysis | Eating Disorders & Weight Management | Endemics | Endocrinology | Glomerulonephritis | Hospitals | Hypertension | Kidney Transplant | Kidney Transplantation | Microbiology | Middle East Health | Nephritis | Peritonitis | Polycystic Kidney Disease | Pyelonephritis | Radiography | Saudi Arabia Health | Study | Transplant Surgery | Transplants | Tuberculosis | Urology & Nephrology | Weight Loss