In Lupus, Time on Dialysis Matters
(MedPage Today) -- Survival in lupus nephritis worsens after 24 months of dialysis (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - May 18, 2018 Category: Primary Care Source Type: news

Identification and Management of Lupus Nephritis Identification and Management of Lupus Nephritis
Find out what there is to know regarding the diagnosis and medical management of lupus nephritis.Journal for Nurse Practitioners (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 12, 2018 Category: Consumer Health News Tags: Nursing Journal Article Source Type: news

Deteriorating Serology May Precede Delayed Lupus Nephritis (CME/CE)
(MedPage Today) -- DLN likely to become more common with rising life expectancy in SLE (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 20, 2018 Category: Rheumatology Source Type: news

Manifestations of Lupus in the Kidney and How to Manage Them Manifestations of Lupus in the Kidney and How to Manage Them
Find out what there is to know regarding the diagnosis of lupus nephritis and the available and emerging treatment strategies.Nephrology Dialysis Transplantation (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 14, 2017 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

How harmful can herbal remedies be? A case of severe acute tubulointerstitial nephritis - Beniwal P, Gaur N, Singh SK, Raveendran N, Malhotra V.
Acute interstitial nephritis (AIN) is a condition in which acute kidney injury (AKI) is characterized by the histological finding of interstitial inflammation. Hyponidd is an ayurvedic drug containing Momordica charantia, Gymnema sylvestre, Swertia chirata... (Source: SafetyLit)
Source: SafetyLit - December 11, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Biomarker Predicts Lupus Nephritis Flares (CME/CE)
(MedPage Today) -- C4d more accurate than conventional complement C3 and C4 (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - December 7, 2017 Category: Rheumatology Source Type: news

Researchers developing home test kit for lupus nephritis flares
(University of Houston) With a four-year $1.4 million grant from the National Institutes of Health (NIH), two University of Houston engineering professors are developing a home test kit for kidney nephritis, or inflammation, in patients who have Systemic Lupus Erythematosus. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 25, 2017 Category: Biology Source Type: news

Medical News Today: Lupus: Probiotics could help to reduce kidney inflammation
Researchers suggest that women with lupus nephritis - that is, lupus-induced kidney inflammation - may benefit from adding Lactobacillus to their diets. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 3, 2017 Category: Consumer Health News Tags: Lupus Source Type: news

First Guidelines Issued on Class II/V Pediatric Lupus Nephritis (CME/CE)
(MedPage Today) -- Focus on timely diagnosis and treatment aimed at complete renal response (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - September 15, 2017 Category: Pediatrics Source Type: news

Selena Gomez Received Kidney Transplant For Lupus Nephritis
Gomez's struggles with lupus may bring more attention to a disease that's still very misunderstood. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - September 15, 2017 Category: Pharmaceuticals Authors: Bruce Y. Lee, Contributor Source Type: news

Snakebite induced thrombotic microangiopathy leading to renal cortical necrosis - Gn YM, Ponnusamy A, Thimma V.
Renal complications from snakebite result in high mortality and morbidity. Acute kidney injury (AKI) occurs in 5-30% of cases. Renal manifestation could include acute tubular necrosis, cortical necrosis, interstitial nephritis, glomerulonephritis, and vasc... (Source: SafetyLit)
Source: SafetyLit - September 13, 2017 Category: International Medicine & Public Health Tags: Non-Human Animals and Insects Source Type: news

What is the Genetic Inheritance of Alport Syndrome?
Discussion Alport Syndrome is a genetic disease classically associated with progressive renal disease often leading to end stage renal disease, variable sensory neuronal deafness and ocular findings (perimacular retinopathy). A. Cecil Alport built on the work of others evaluating families with nephritis and/or hematuria. However he very clearly describes the third generation of a family with an X-linked dominant pattern and also emphasizes the syndrome’s associated deafness. Alport writes: “It will be seen from this that nearly all the children of three generations of one family suffer from hematuria or nep...
Source: PediatricEducation.org - August 28, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Aurinia begins voclosporin dosing in Phase III trial for LN
Canadian-based biopharmaceutical firm Aurinia Pharmaceuticals has begun dosing patients in the Phase III AURORA clinical trial of voclosporin to treat lupus nephritis (LN). (Source: Drug Development Technology)
Source: Drug Development Technology - May 18, 2017 Category: Pharmaceuticals Source Type: news

Boehringer begins enrolment in Phase II trial of BI 655064 to treat lupus nephritis
Pharmaceutical company Boehringer Ingelheim has begun patient enrolment in the Phase II clinical trial of BI 655064 for the treatment of lupus nephritis (LN). (Source: Drug Development Technology)
Source: Drug Development Technology - May 10, 2017 Category: Pharmaceuticals Source Type: news

Phase II Trial now enrolling patients with Lupus Nephritis
(Source: Boehringer Ingelheim Corporate News)
Source: Boehringer Ingelheim Corporate News - May 10, 2017 Category: Research Source Type: news

Renal Data Reassuring in Lupus Pregnancy (CME/CE)
(MedPage Today) -- De novo nephritis numbers were miniscule in prospective study (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - May 4, 2017 Category: OBGYN Source Type: news

Mid-Stage Voclosporin Data Look Good in Lupus Nephritis (CME/CE)
(MedPage Today) -- 48-week findings of AURA-LV reported high rates of complete, partial remission (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - April 21, 2017 Category: Primary Care Source Type: news

What Causes Uveitis?
Discussion Inflammation of the middle layer of the eye, or uvea, is termed uveitis. Uveitis can be divided into anterior, intermediate or posterior uveitis by involving the anterior (iris and ciliary body), intermediate (vitreous) or posterior (choroid and usually retina) compartments. Panuveitis involves all 3 compartments. Duration can also be used to classify uveitis. Acute is 6 weeks and> 3 months is chronic persistent uveitis. Episodic periods of inactivity and reactivity that last more than 3 months are called recurrent uveitis. A third way to characterize uveitis is if it is granulomatous or not. Uveitis increase...
Source: PediatricEducation.org - April 3, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Editorial: federal restrictions on gun research should be lifted - Leopold SS.
Question: What do Parkinson ’s disease, sepsis, liver disease, gun violence, traffic accidents, poisoning, and nephritis have in common? Answer: They all kill about 30,000 people a year in the United States (stated another way, about 10 deaths per 1... (Source: SafetyLit)
Source: SafetyLit - March 31, 2017 Category: Global & Universal Tags: Commentary Source Type: news

Infection Rates High in Kids with SLE (CME/CE)
(MedPage Today) -- Highest rates seen in those with lupus nephritis (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - February 23, 2017 Category: Infectious Diseases Source Type: news

Lupus Nephritis Treatment
Title: Lupus Nephritis TreatmentCategory: Doctor's& Expert's views on SymptomsCreated: 3/1/2002 12:00:00 AMLast Editorial Review: 1/12/2017 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - January 12, 2017 Category: Rheumatology Source Type: news

Novel Agent Showing Promise, a First in Lupus Nephritis Novel Agent Showing Promise, a First in Lupus Nephritis
An induction regimen that includes a calcineurin inhibitor can help patients with acute lupus nephritis achieve complete or partial remission, early research suggests.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 21, 2016 Category: Consumer Health News Tags: Nephrology News Source Type: news

Aurinia reports positive AURA –LV study outcome of voclosporin in treating lupus nephritis
Canadian-based clinical stage bio-pharmaceutical company Aurinia has reported positive results from its AURA –LV study of voclosporin in combination with mycophenolate mofetil against placebo to treat lupus nephritis (LN). (Source: Drug Development Technology)
Source: Drug Development Technology - October 2, 2016 Category: Pharmaceuticals Source Type: news

Pathophysiology and Treatment of Human Lupus Nephritis Pathophysiology and Treatment of Human Lupus Nephritis
Gain a better understanding of the pathophysiology of lupus nephritis and learn about the best therapeutic strategies for this disease.Current Opinion in Rheumatology (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - September 12, 2016 Category: Intensive Care Tags: Rheumatology Journal Article Source Type: news

Medical News Today: All You Need to Know About Nephritis
This article looks at the causes, symptoms, and treatment of nephritis. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 28, 2016 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Voclosporin Said to Show Benefit in Lupus Nephritis
(MedPage Today) -- Significant responses seen in phase IIb trial (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - August 24, 2016 Category: Primary Care Source Type: news

Treatment for Pediatric MLN Remains Irregular (CME/CE)
(MedPage Today) -- Study found variation in clinical practice for membranous lupus nephritis (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - August 23, 2016 Category: Rheumatology Source Type: news

Vitamin D Deficiency Is As Dangerous As Smoking
The advice you’re getting from your doctor, the TV and even the Surgeon General is so wrong, it’s scary. They’re all busy telling you to stay out of the sun. But Swedish researchers recently discovered that nonsmokers who avoid the sun have a life expectancy similar to smokers who spend a lot of time in the sun. Staying out of the sun is as dangerous as smoking.1 It doesn’t surprise me. I tell all my patients sunlight exposure is essential to our health because it is the best source of vitamin D… possibly the most important nutrient we know of. Mainstream medicine still doesn’t recogni...
Source: Al Sears, MD Natural Remedies - May 19, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news

Lead and Kidneys
The recent news about lead exposure from city water in Flint, Michigan, has renewed many people's concerns about an environmental cause of kidney disease. For years, extraordinary efforts have been made to eradicate environmental lead exposure by eliminating lead based gasoline, stopping the sale of lead based paints, removing lead based paint from older homes, and monitoring of blood lead levels in children and the public by local health departments. All of these activities have resulted in consistently fewer reports of lead-associated kidney disease. Environmental exposure from lead in water has only recently been recogn...
Source: Healthy Living - The Huffington Post - March 23, 2016 Category: Consumer Health News Source Type: news

Acute interstitial nephritis following snake envenomation: a single-center experience - Priyamvada PS, Shankar V, Srinivas BH, Rajesh NG, Parameswaran S.
OBJECTIVES: To identify the clinical and histopathological characteristics of patients who develop acute interstitial nephritis (AIN) following snake envenomation. METHODS: A retrospective analysis of patients diagnosed with snake envenomation-indu... (Source: SafetyLit)
Source: SafetyLit - March 20, 2016 Category: Global & Universal Tags: Non-Human Animals and Insects Source Type: news

Autoimmune attack underlying kidney failure
Interstitial nephritis, a common cause of kidney failure, has a complex and largely unknown pathogenesis. In a new published paper, a team of researchers shows how interstitial nephritis can develop from an autoimmune attack on the kidney’s collecting duct. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 16, 2016 Category: Science Source Type: news

Nick Cannon Looks Back On His 'Super Scary' Lupus Diagnosis
Nick Cannon didn't know anything about lupus nephritis when he was first diagnosed in 2012, so hearing that some of his other health complications were the result of the autoimmune disease came as a surprise. It was only after Cannon did some research on the condition, which had resulted in kidney failure and blood clots in his lungs, that he began to understand and take care of his well-being. Now he hopes his story encourages others to do the same. "[Y]ou realize that this is something that you can live with and actually overcome with the proper research and with the proper support system," he told HuffPos...
Source: Healthy Living - The Huffington Post - February 24, 2016 Category: Consumer Health News Source Type: news

Nephritis in Sjögren's Syndrome Responds to MMF (CME/CE)
(MedPage Today) -- Modest increases in estimated GFR seen with the immunosuppressant (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 18, 2016 Category: Rheumatology Source Type: news

How Terrified Should We Be?
After every terrorist attack we go through a period of overwhelming fear that we will individually be the target of terrorism. Recently a man told me that he will avoid going to crowded areas of the city because he fears being killed by a terrorist. A woman fears flying because she fears the plane will be blown up by a terrorist. Years ago, after 9/11, a woman told me that she feared "Arab-looking men" in the subway. And, after 9/11, years ago, a family moved to Colorado from New York City because of their fear of terrorism. Fear pervaded the lives of many people and, once again, after the attack in San Bernardin...
Source: Healthy Living - The Huffington Post - December 23, 2015 Category: Consumer Health News Source Type: news

Nephrologists to help find treatment for lupus
(Texas Tech University Health Sciences Center El Paso) Nephrologists at Texas Tech University Health Science Center El Paso have been invited to participate in a national consortium that's investigating the key causes of lupus nephritis -- an autoimmune disease that can cause kidney failure. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 16, 2015 Category: Biology Source Type: news

CellCept Useful for Lupus Nephritis in Hispanics (CME/CE)
(MedPage Today) -- In comparison, azathioprine had more than twice the risk of flares during maintenance (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - September 29, 2015 Category: Urology & Nephrology Source Type: news

Lupus Nephritis Affects One Third of Patients With LupusLupus Nephritis Affects One Third of Patients With Lupus
Patients with lupus who have nephritis had high rates of end-stage renal disease and death and a lower quality of life, a longitudinal study showed. Medscape Medical News (Source: Medscape Nephrology Headlines)
Source: Medscape Nephrology Headlines - September 22, 2015 Category: Urology & Nephrology Tags: Rheumatology News Source Type: news

Lupus Nephritis Treatment
Title: Lupus Nephritis TreatmentCategory: Doctor's & Expert's views on SymptomsCreated: 3/1/2002 12:00:00 AMLast Editorial Review: 9/16/2015 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - September 16, 2015 Category: Rheumatology Source Type: news

Tacrolimus Comes Out Tops for Lupus Nephritis (CME/CE)
(MedPage Today) -- Meta-analysis compares the available immunosuppressants. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - July 25, 2015 Category: Rheumatology Source Type: news

Lupus Nephritis Response Criteria in Lupus Activity IndicesLupus Nephritis Response Criteria in Lupus Activity Indices
To advance the knowledge of how to treat lupus nephritis, well-designed clinical trials informed by prior randomized controlled trials are needed. Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 21, 2015 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Stem cell transplant alleviates symptoms in lupus animal models
(Cell Transplantation Center of Excellence for Aging and Brain Repair) Systemic lupus erythematosus is an autoimmune disease that produces autoantibodies and subsequent immune reactions that can be life threatening when major organs are invaded. When mesenchymal stem cells derived from human bone marrow were transplanted into mice modeled with SLE, inflammation was reduced and nephritis attenuated. The researchers found that MSCs slowed the progression of SLE by suppressing the emergence of the damaging antibodies that are produced with the help of follicular T helper cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 14, 2015 Category: Global & Universal Source Type: news

Lupus Nephritis Therapeutic Development Pipeline Review H1 2015 Market...
RnRMarketResearch.com adds “Lupus Nephritis – Pipeline Review, H1 2015” to its store. The report provides an overview of the Lupus Nephritis’s therapeutic pipeline.(PRWeb June 10, 2015)Read the full story at http://www.prweb.com/releases/lupus-nephritis-pipeline/review-h1-2015-market/prweb12779381.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - June 12, 2015 Category: Pharmaceuticals Source Type: news

Lupus Nephritis: Multiple Factors for Tx Success (CME/CE)
(MedPage Today) -- Absence of anti-dsDNA antibodies, cyclophosphamide induction linked to better outcomes. (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - May 29, 2015 Category: Urology & Nephrology Source Type: news

Male Fetal Cells May Protect Women With Lupus Nephritis (CME/CE)
(MedPage Today) -- SLE female patients previously pregnant with male fetuses had better renal function. (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - April 24, 2015 Category: Rheumatology Source Type: news

Proton pump inhibitors increase risk of acute kidney injury
3 out of 5 stars Proton pump inhibitors and the risk of acute kidney injury in older patients: a population-based cohort study. Antoniou T et al. CMAJ Open 2015;Apr;3:E166-E171. Full Text Previous studies have suggested that use of proton pump inhibitors (PPIs) increases risk of acute interstitial nephritis, especially in elderly patients. Using information from  several large computerized databases containing medical information about patients in Ontario, Canada, the authors carried out a population-based cohort study of patients in Ontario aged 66 years and older who were newly prescribed  P...
Source: The Poison Review - April 23, 2015 Category: Toxicology Authors: Leon Tags: Medical acute kidney injury interstitial nephritis lansoprazole omeprazole proton pump inhibitor Source Type: news

Drug-induced glomerular disease: direct cellular injury - Markowitz GS, Bomback AS, Perazella MA.
The potential of medications to cause kidney injury is well known. Although nephrotoxicity is most commonly associated with injury in the tubulointerstitial compartment as either acute tubular necrosis or acute interstitial nephritis, a growing body of lit... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - April 17, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Proton pump inhibitors are associated with an increased risk of acute kidney failure and acute interstitial nephritis in older patients
(Source: St. Michael's Hospital News and Media)
Source: St. Michael's Hospital News and Media - April 16, 2015 Category: Hospital Management Tags: Hospital News Source Type: news

Azathioprine and Mycophenolate Mofetil Comparable in Lupus NephritisAzathioprine and Mycophenolate Mofetil Comparable in Lupus Nephritis
In a 10-year follow-up study, European investigators found no difference in long-term outcomes between patients given mycophenolate mofetil (MMF) or azathioprine as maintenance therapy for proliferative lupus nephritis. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 14, 2015 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Lupus Nephritis Histology Predicts Long-Term Outcomes (CME/CE)
(MedPage Today) -- Class IV disease associated with poorer 5-year remission rates. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 13, 2015 Category: Primary Care Source Type: news

Two Regimens Equivalent in Lupus Nephritis (CME/CE)
(MedPage Today) -- 10-year study confirms: it's a toss-up between mycophenolate mofetil and azathioprine. (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 11, 2015 Category: Primary Care Source Type: news