TORdx LUNG Test for Donor Lung Assessment: Interview with Eric Brouwer, Chief Scientific Officer at SQI Diagnostics
SQI Diagnostics, a medtech company based in Canada, is developing the TORdx LUNG Test. The technology is intended to assist clinicians in assessing donor lungs in their suitability for transplantation. At present, clinicians typically assess donor lungs using qualitative variables, such as donor health and lung size. One of the most important factors, lung inflammation, is difficult to assess, and clinicians will often play it safe and reject an organ if there is any doubt about it. This means that lungs that might actually be suitable for transplantation are often rejected, further compounding the lack of donor organs....
Source: Medgadget - July 18, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Cardiac Surgery Exclusive Medicine Thoracic Surgery lung transplant sqi diagnostics Source Type: blogs

PicnicHealth Raises a $60m Series C to Expand Patient-centered Real-world Data
PicnicHealth, a patient-centered health technology company, today announced the closing of a $60 million Series C financing led by new investor B Capital Group. Existing investors Felicis Ventures and Amplify Partners also joined the round, bringing the total PicnicHealth has raised to more than $100 million. The company also announced plans to build 30 new patient-centered real-world data cohorts, and the addition of Adam Seabrook, Partner at B Capital Group, to the PicnicHealth board of directors. PicnicHealth takes a patient-centered approach to building deep real-world datasets for life sciences researchers. This compl...
Source: EMR and HIPAA - July 1, 2022 Category: Information Technology Authors: Healthcare IT News Tags: Analytics/Big Data Health IT Company Healthcare IT Adam Seabrook Amplify Partner B Capital Group Felicis Ventures Health IT Funding Health IT Fundings Health IT Investment Noga Leviner PicnicHealth Real-World Data Robert Mittendo Source Type: blogs

Checking urine eosinophils to evaluate for acute interstitial nephritis
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - March 26, 2019 Category: Internal Medicine Tags: hospital medicine nephrology quality and safety Source Type: blogs

MKSAP: 25-year-old man with dark-colored urine
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 25-year-old man is evaluated for dark-colored urine for 2 days, swelling of the face and hands for 1 day, and severe headaches this morning. He reports having an upper respiratory tract infection 1 week ago with fever, sore throat, and swollen glands, but had otherwise felt well. Medical history is otherwise unremarkable, and he takes no medications. On physical examination, temperature is 37.2 °C (99.0 °F), blood pressure is 180/90 mm Hg, pulse rate is 88/min, and respiration rate is 14/min. Cardiopulmonary...
Source: Kevin, M.D. - Medical Weblog - August 25, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Infectious Disease Nephrology Source Type: blogs

No, I ’m not settling for family medicine
During a recent internal medicine rotation, a senior resident expressed disappointment that I’ve chosen a career in family medicine. He was concerned that my talents would be wasted, because — in his words — I wouldn’t get to care for the “more complex patients” he sees in internal medicine. Although I appreciated his confidence in my abilities, I felt my heart sink, as it does each time I am faced with misinformed perceptions about family medicine. I thought back to my last family medicine rotation, and the following patients came to mind: A young woman with a previous diagnosis of idi...
Source: Kevin, M.D. - Medical Weblog - May 16, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/lauren-abdul-majeed" rel="tag" > Lauren Abdul-Majeed < /a > Tags: Physician Primary care Source Type: blogs

Medical errors are not the third leading cause of death
I read it again this week, and I wonder why the editors of our medical journals continue to perpetuating this falsehood. An article in a prominent journal stated again that medical errors are the third leading cause of death in the United States. We all know this is not the case, and yet editors continue to let this be stated in their journals as if it were fact. Ever since the offending article was published last year making this ridiculous claim, other authors have perpetuated it as if it were true. Yet it is painfully obvious to every practicing physician that it is not true. The top ten causes of death, according to th...
Source: Kevin, M.D. - Medical Weblog - February 13, 2017 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/cory-fawcett" rel="tag" > Cory Fawcett, MD < /a > Tags: Physician Malpractice Source Type: blogs

MKSAP: 54-year-old woman is evaluated for fatigue, anorexia, polyuria, and nocturia
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 54-year-old woman is evaluated for fatigue, anorexia, polyuria, and nocturia of several weeks’ duration. She had otherwise felt well until the onset of her current symptoms. Medical history is significant for autoimmune pancreatitis diagnosed 1 year ago, treated with a prednisone taper that was completed 8 months ago with resolution of her symptoms. She takes no medications. On physical examination, temperature is 36.2 °C (97.2 °F), blood pressure is 110/58 mm Hg, pulse rate is 72/min, and respiration ...
Source: Kevin, M.D. - Medical Weblog - July 30, 2016 Category: Journals (General) Authors: < a href="http://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Nephrology Source Type: blogs

LITFL Review 217
Welcome to the 217th LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chuck of FOAM. The Most Fair Dinkum Ripper Beauts of the Week How do we reach deep within to find empathy when we feel at our worst? By remembering the other side of the story, writes Phil Berry in his blog.“The trick at such times is to access the human in ourselves” [SO]   The Best of #FOAMed Em...
Source: Life in the Fast Lane - January 31, 2016 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review Source Type: blogs

Treatment Options In Goodpastures.
Goodpastures Syndrome. A rapidly progressive form of kidney disease associated with antibodies directed against the structural components of the functional subunits of the kidney and the lung. The disease therefore gives rise to both lung and kidney pathology a situation termed pulmonary renal syndrome. The exact cause is unknown. It is considered an autoimmune disorder (other autoimmune disorder’s that affect the kidney include Lupus Nephritis). The bodies own immune system is responsible for targeting both lung and kidney tissues. The initial immune system activation may occur in response to viral infection or even the...
Source: All Kidney News - September 29, 2015 Category: Urology & Nephrology Authors: jadhavbca Tags: Kidney News Treatment Options Source Type: blogs

Don’t Smoke ’Em if You Got ’Em
A 22-year-old man with no past medical history presented to the emergency department with altered mental status. He was brought in by police who reported using a TASER on him three times after he became violent with them. His friends report he smoked K2. His initial vital signs included a temperature of 99.9°F, a heart rate of 137 bpm, blood pressure of 151/76 mm Hg, a respiratory rate of 22 bpm, and pulse oximetry of 98% on room air. The patient was agitated and combative, and was placed in four-point restraints.   K2 is a synthetic cannabinoid. Other commonly used synthetic cannabinoids include spice, moon rocks, com...
Source: The Tox Cave - July 1, 2015 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Don’t Smoke ’Em if You Got ’Em
A 22-year-old man with no past medical history presented to the emergency department with altered mental status. He was brought in by police who reported using a TASER on him three times after he became violent with them. His friends report he smoked K2. His initial vital signs included a temperature of 99.9°F, a heart rate of 137 bpm, blood pressure of 151/76 mm Hg, a respiratory rate of 22 bpm, and pulse oximetry of 98% on room air. The patient was agitated and combative, and was placed in four-point restraints.   K2 is a synthetic cannabinoid. Other commonly used synthetic cannabinoids include spice, moon rocks, comat...
Source: The Tox Cave - July 1, 2015 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

MKSAP: 53-year-old woman with swelling of the face, hands, and feet
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 53-year-old woman is evaluated for a 3-month history of swelling of the face, hands, and feet. She has untreated hepatitis C virus infection. She takes lithium for bipolar disorder. She has no additional symptoms. On physical examination, temperature is normal, blood pressure is 134/93 mm Hg, pulse rate is 71/min, and respiration rate is 18/min. Bilateral periorbital edema and swelling of the hands and legs are noted. The remainder of the examination is unremarkable. Laboratory studies: Complete blood count...
Source: Kevin, M.D. - Medical Weblog - May 30, 2015 Category: Journals (General) Authors: Kevin Tags: Conditions Nephrology Source Type: blogs

CKD, 4 L of coca cola, NSAIDs for “arthritis”
40 something year old woman gets referred to a colleague for CKD 141 115 31 102 2.8 14 2.0 The referring physician has given her 40 mEq of potassium each day.  The creatinine has not changed significantly in 6 months. She takes NSAIDs for “arthritis” She drinks 4 L of coca cola each day 1. What is her diagnosis? I have added this case to my “Learning How to Think like a Clinician” talk. The nephrologist who saw this patient diagnosed it quickly. At morning report, I diagnosed it quickly, but none of the students or residents new it. For the nephrologist and me it was a quick System 1 (patte...
Source: DB's Medical Rants - March 21, 2015 Category: Internal Medicine Authors: rcentor Tags: Acid-Base & Lytes Source Type: blogs

Top stories in health and medicine, March 16, 2015
From MedPage Today: Lupus Nephritis Histology Predicts Long-Term Outcomes. In lupus nephritis (LN), renal histology with World Health Organization (WHO) class IV pathology predicts a decreased long-term remission rate. Biosimilars Must Be Tightly Regulated. Following the approval of the first biosimilar agent in the United States — Zarxio, for the prevention of infections in patients with cancer undergoing chemotherapy — the American College of Rheumatology (ACR) has issued a position statement on biosimilars, given the expectation that there soon may be biosimilars for biologics used in rheumatology. CT No B...
Source: Kevin, M.D. - Medical Weblog - March 16, 2015 Category: Journals (General) Authors: Tags: News Cancer Heart Rheumatology Source Type: blogs

What is a serious diagnosis?
The serious diagnosis is a polite middle-aged woman with a hopeful smile sitting on the side of the bed, with her husband in the chair across from her, as you carefully tell them what it means to have ovarian cancer. The serious diagnosis is the teenager who just found out he has lupus nephritis — without any other signs or symptoms of lupus — and that he might be on hemodialysis soon if high-dose steroids and chemotherapy don’t work.  He has a three-month-old infant. Continue reading ... Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out h...
Source: Kevin, M.D. - Medical Weblog - February 5, 2015 Category: Journals (General) Authors: Tags: Physician Primary care Source Type: blogs