Scientists discover potential treatment approaches for polycystic kidney disease
Innovative disease modeling and gene editing techniques begin to answer long-standing questions. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - April 4, 2024 Category: American Health Source Type: news

Regulus Therapeutics Reports Fourth Quarter and Year-End 2023 Financial Results and Recent Updates
Positive topline data from the second cohort of patients in Phase 1b Multiple-Ascending Dose (MAD) Clinical Trial of RGLS8429 for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Oversubscribed $100 million private placement; expected to extend cash runway into H1... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - March 21, 2024 Category: Pharmaceuticals Tags: ERN Source Type: news

What's the difference between kidney cysts and polycystic kidney disease?
March is  National Kidney Month, which makes this a good time to learn more about the difference between two kidney disorders — kidney cysts and polycystic kidney disease. Your kidneys are situated in the back of your abdomen under your lower ribs, one on each side of your spine. One of the important jobs of the kidneys is to clean the blood. As blood moves through the body, it picks up extra fluid, chemicals and waste.… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 2, 2024 Category: Databases & Libraries Source Type: news

Racial Disparities in ADPKD
Learn more about how racial disparities in health care affect Black people and other people of color with autosomal dominant polycystic kidney disease (ADPKD). (Source: WebMD Health)
Source: WebMD Health - January 10, 2024 Category: Consumer Health News Source Type: news

Regulus Therapeutics Announces Completion of Enrollment in Third Cohort of Phase 1b Multiple-Ascending Dose (MAD) Clinical Trial of RGLS8429 for the Treatment of Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD)
SAN DIEGO, Jan. 2, 2024 /PRNewswire/ -- Regulus Therapeutics Inc. (Nasdaq: RGLS), a biopharmaceutical company focused on the discovery and development of innovative medicines targeting microRNAs (the "Company" or "Regulus"), today announced it has completed enrollment in the third cohort... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - January 2, 2024 Category: Pharmaceuticals Tags: TRI Source Type: news

Science Saturday: Confronting polycystic kidney disease, a silent killer
Researchers at the Polycystic Kidney Disease (PKD) Center at Mayo Clinic now use artificial intelligence (AI) to assess total kidney volume, generating results in a matter of seconds. The goal is to help diagnose PKD. When Fouad Chebib, M.D., was 16 years old, his father sat him and his sister down and told them he had polycystic kidney disease (PKD). The kidneys of people with the condition become jammed with dense, fluid-filled sacs, causing them to increase in size… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - August 12, 2023 Category: Databases & Libraries Source Type: news

Regulus Therapeutics Announces Appointment of Preston S. Klassen, M.D. to its Board of Directors
SAN DIEGO, June 23, 2023 -- (Healthcare Sales & Marketing Network) -- Regulus Therapeutics Inc. (Nasdaq: RGLS), a biopharmaceutical company focused on the discovery and development of innovative medicines targeting microRNAs (the "Company" or &q... Biopharmaceuticals, Personnel Regulus Therapeutics, microRNA, Autosomal Dominant Polycystic Kidney Disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 23, 2023 Category: Pharmaceuticals Source Type: news

Potential avenues toward gene therapies for polycystic kidney disease
A Yale-led study pinpointed a protein which can cause nearly 80% of cases, a promising therapeutic target for treating the potentially lethal genetic disease. (Source: Yale Science and Health News)
Source: Yale Science and Health News - April 10, 2023 Category: Universities & Medical Training Source Type: news

Mayo Clinic Minute: Using AI to predict kidney failure in patients with polycystic kidney disease
Kidney failure can be caused by many reasons: diabetes, high blood pressure, autoimmune diseases and polycystic kidney disease, or PKD. PKD is an inherited disease that causes cysts to form around your kidneys. The most common form of PKD is autosomal dominant polycystic kidney disease (ADPKD), where it is most often diagnosed in adults between the ages of 30 and 40.   Dr. Fouad Chebib, a Mayo Clinic nephrologist and expert on polycystic kidney disease, says patients understand… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - April 6, 2023 Category: Databases & Libraries Source Type: news

Consumer Health: What's the difference between kidney cysts and polycystic kidney disease?
March is National Kidney Month, which makes this a good time to learn more about the difference between two kidney disorders — kidney cysts and polycystic kidney disease. Your kidneys are situated in the back of your abdomen under your lower ribs, one on each side of your spine. One of the important jobs of the kidneys is to clean the blood. As blood moves through the body, it picks up extra fluid, chemicals and waste.… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 3, 2023 Category: Databases & Libraries Source Type: news

My Dialysis Machine Works as My Kidneys, for Now
If you have autosomal dominant polycystic kidney disease (ADPKD), you may need dialysis at some point. Here’s what to expect. (Source: WebMD Health)
Source: WebMD Health - November 21, 2022 Category: Consumer Health News Source Type: news

Reducing the severity of polycystic kidney disease
A team of Yale researchers have identified a specific protein that when activated can help reduce the severity of this common kidney condition. (Source: Yale Science and Health News)
Source: Yale Science and Health News - October 25, 2022 Category: Universities & Medical Training Source Type: news

Mayo Clinic Q & amp;A podcast: Father-daughter duo taking part in Transplant Games of America
Carly Kelly was born with autosomal recessive polycystic kidney disease, a disease that not only affects the kidneys, but also can lead to liver problems. She spent the first month of her life in the Neonatal ICU at Mayo Clinic, where physicians told Carly's family she would eventually need a kidney transplant. "I was the first one to register as a donor," says Tim Kelly, Carly's father. "And I was so blessed to be a… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - July 29, 2022 Category: Databases & Libraries Source Type: news

Racial Disparities ID'd in Autosomal Dominant Polycystic Kidney Disease
TUESDAY, July 12, 2022 -- Black and Hispanic patients with autosomal dominant polycystic kidney disease (ADPKD) reach kidney failure earlier than White patients and are less likely to receive a kidney transplant preemptively and after initiating... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 12, 2022 Category: Pharmaceuticals Source Type: news

Ask the Mayo Mom: Polycystic kidney disease can affect children, too
Polycystic kidney disease is an inherited disorder where clusters of cysts develop within the kidneys, causing the kidneys to enlarge and lose function over time. The cysts, which are noncancerous sacs containing fluid, vary in size, and they can grow to be large. This disorder can occur in children and adults. The two main types of polycystic kidney disease, caused by different genetic flaws, are: Autosomal dominant polycystic kidney disease (ADPKD). Signs and symptoms of ADPKD often develop… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - May 13, 2022 Category: Databases & Libraries Source Type: news