Spectrum of the neurologic manifestations in childhood-onset cryopyrin-associated periodic syndrome.

CONCLUSION: Half of the children with CAPS exhibited neurologic manifestations with varying degrees of severity. Increased understanding and awareness of this rare but treatable syndrome among neurologists is essential. If remains untreated and unrecognized, this autoinflammatory syndrome could lead to significant morbidity and mortality. Besides complete resolution of systemic symptoms, anti-interleukin-1 treatment may also prevent progression of neurologic findings when initiated in the early stage of the disease.
PMID: 30967326 [PubMed - as supplied by publisher]

Source: European Journal of Paediatric Neurology - March 27, 2019 Category: Neurology Authors: Kilic H, Sahin S, Duman C, Adrovic A, Barut K, Turanli ET, Yildirim SR, Kizilkilic O, Kasapcopur O, Saltik S Tags: Eur J Paediatr Neurol Source Type: research