Molecules, Vol. 23, Pages 3315: Chenodeoxycholic Acid from Bile Inhibits Influenza A Virus Replication via Blocking Nuclear Export of Viral Ribonucleoprotein Complexes

In conclusion, as an endogenous physiological small molecule, CDCA can inhibit IAV replication in vitro, at least in part, by blocking vRNP nuclear export, and affords further studies for development as a potential antiviral agent against IAV infections.

Source: Molecules - December 14, 2018 Category: Chemistry Authors: Ling Luo Weili Han Jinyan Du Xia Yang Mubing Duan Chenggang Xu Zhenling Zeng Weisan Chen Jianxin Chen Tags: Article Source Type: research