Chronic Kidney Disease (CKD) in the U.S. Hemophilia Population: A Cohort Study
The objective of this study is to determine the prevalence of CKD and CKD risk factors among older men with moderate and severe hemophilia.Methods: This CKD cohort study is an extension of a U.S. national study sponsored by the American Thrombosis and Hemostasis Network (ATHN). The study, entitled ATHN 1: A Cross-Sectional Analysis of Cardiovascular Disease (CVD) in the Hemophilia Population, began enrollment in 10/2012. Inclusion criteria are men with moderate or severe congenital hemophilia A or B (FVIII or IX level ≤ 5%), age 54-73. Men with an additional bleeding disorder (besides liver dysfunction) were excluded. In this extension study, CKD risk factors, historical creatinine levels, and history of renal events were obtained from patient interview and chart review after obtaining informed consent. Glomerular filtration rate (GFR) values were calculated using the CKD-EPI equation and compared to values in the general population using the NHANES dataset (Coresh et al., JAMA 2007). CKD is defined as the presence of either kidney damage or decreased kidney function with GFR
A new study examines the question of whether thromboprophylaxis is needed to prevent VTE complications after adrenalectomy.Journal of the Endocrine Society
(Society of Interventional Radiology) Training interventional radiologists to perform endovascular thrombectomies results in positive outcomes for patients experiencing stroke, according to a study presented today at the Society of Interventional Radiology Annual Scientific Meeting. Expanding access to this treatment provides patients timely access to this gold-standard treatment.
ConclusionWe found a significant positive association between dietary acid load and hypertension. Further studies, particularly those with prospective nature, are needed to confirm our findings.
Our weekly DiabetesMine series of cartoons and memes for the diabetes community features a cartoon by Jon Carter.
This study assed the effect of saffron as a neuroprotective natural product in cerebral ischemia in human.Study designPatients with acute ischemic stroke were randomly allocated to receive either routine stroke care (control group, n = 20) or routine care plus aqueous extract of saffron capsule (200 mg/day) (saffron-treated group, n = 19). Both groups were monitored during their four-day hospital stay and the three-month follow-up period. The groups were compared in terms of short- and long-term effects of saffron capsules using the National Institute of Health Stoke Scale (NIHSS), Barthel Scale, and serum neuron...
ConclusionsThis study indicates that a substantial proportion of subjects with OA experience severe asthma and identifies potentially modifiable risk factors for severe OA that should be targeted in order to reduce the adverse impacts of the disease.
This study aimed to compare the magnitude of educational inequalities in self-reported and examination-based hypertension and hypercholesterolemia and to assess the impact of self-reported measurement error on health inequality indicators.MethodsWe used the Portuguese National Health Examination Survey data (n = 4911). The slope index of inequality (SII) and the relative index of inequality (RII) were used to determine the magnitude of absolute and relative education-related inequalities.ResultsAmong the 25 –49-year-old (yo) men, absolute and relative inequalities were smaller for self-reported than for...
This study adopted hydrophilic and positively charged α-poly-l-lysine (αPLL) as the entrapment matrix for the immobilization of negatively charged glucose oxidase (GOx) and ferricyanide (FIC) on SPCEs to construct a disposable second-generation glucose biosensor. The αPLL modification is shown to facilitate the redox kinetics of FIC and ferrocyanide on the SPCEs. The SPCEs coated with 0.5 mM GOx, 99.5 mM FIC, and 5 mM αPLL had better sensitivity for glucose detection due to the appreciable effect of protonated αPLL on the promotion of electron transfer between GOx and FIC. ...
' A reasonable HbA1c goal for many nonpregnant adults with diabetes is
More News: Bleeding | Cardiology | Cardiovascular | Chronic Kidney Disease | Databases & Libraries | Diabetes | Diabetes Mellitus | Eating Disorders & Weight Management | Endocrinology | Haemophilia | Heart | Hemophilia | Hepatitis | Hepatitis C | History of Medicine | Hypertension | Ischemic Stroke | Laboratory Medicine | Liver | Obesity | Pediatrics | Pfizer | Stroke | Study | Thrombosis | Urology & Nephrology