Metabolic syndrome as cardiovascular risk factor in childhood cancer survivors

Over the past decades, survival rates of childhood cancer have increased considerably from 5-30% in the early seventies to current rates exceeding 80% (SEER Cancer Statistics Review, 1975-2014 and National Cancer Institutie [Internet], 2016). This is due to the development of effective chemotherapy, surgery, radiotherapy and stem cell transplantation (SCT), combined with an optimized stratification of therapy and better supportive care regimens. These improved survival rates currently result in an ongoing increasing number of survivors (Meadows, 2003), which in turn resulted in increased awareness of late side effects of treatment for childhood cancer, and research investigating these late sequelae.

Source: Critical Reviews in Oncology Hematology - November 3, 2018 Category: Cancer & Oncology Authors: V.G. Pluimakers, M. van Waas, S.J.C.M.M. Neggers, van den Heuvel-Eibrink Source Type: research