Up-Regulation Thioredoxin Inhibits Advanced Glycation End Products-Induced Neurodegeneration

Conclusion: Up-regulating Trx inhibited neurodegeneration induced by AGEs. The underlying mechanism may be related to inhibit Txnip/mTOR pathway-mediated autophagy.Cell Physiol Biochem 2018;50:1673 –1686
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research