Clinical stage and histological type of the most common carcinomas diagnosed in young adults in a reference cancer hospital

OBJECTIVES: Cancer in young adults represents a great challenge, both biologically and socially, and understanding the unique characteristics of neoplasms in this age group is important to improving care. We aimed to evaluate the most common carcinomas and their characteristics, such as histological type and clinical stage, in young adults in the largest cancer hospital in Latin America. METHODS: The hospital registry was consulted for the period between 2008 and 2014. Young adults were defined as individuals aged 18 to 39 years, and older adults were defined as individuals aged 40 years and older. Differences between age groups were assessed through chi-square tests. RESULTS: Of the 39,389 patients included, 3,821 (9.7%) were young adults. Among the young adults, the most frequent cancer types were the following: breast, lymph node, colorectal, thyroid, testicle, hematopoietic and reticuloendothelial, uterine cervix, brain, soft tissue and stomach; these sites accounted for 74.5% of the observed tumors. Breast, colorectal and stomach cancers were more frequently diagnosed at advanced stages in young adults than in older adults (p
Source: Clinics - Category: General Medicine Source Type: research

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In this study, microarray analysis was used for gene expression profiling in rat prostate tissue after exposure to EDCs and sex hormones over multiple time points (prepubertal through adulthood). We used dorsolateral prostate tissues from Sprague-Dawley rats (male offspring) and postnatally administered estradiol benzoate (EB) on postnatal days (PNDs) 1, 3, and 5, followed by treatment with additional hormones [estradiol (E) and testosterone (T)] on PNDs 90-200, as described by Ho et al. Microarray analysis was performed for gene expression profiling in the dorsolateral prostate, and the results were validated via qRT-PCR....
Source: Journal of Toxicological Sciences - Category: Toxicology Tags: J Toxicol Sci Source Type: research
CONCLUSIONS: Type 1 diabetes in both genders and all ages was associated with significantly elevated SMRs for all-cause and mostly for diabetes per se and renal disease. PMID: 32741854 [PubMed - as supplied by publisher]
Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
Do you guys think there is enough volume to support an outpatient interventional cancer pain &cancer rehab practice? I will be starting my PM&R residency training at one of the top programs in the country after this academic year (am an prelim medicine intern right now). And I ultimately want to help cancer survivors. I think with the continuing improvements with cancer treatments (most recently with immunotherapy), cancer will be/is a chronic disease with debilitating side effects that... cancer pain only practice
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Publication date: Available online 4 August 2020Source: Academic RadiologyAuthor(s): Eric S. Fair, Petar Duvnjak
Source: Academic Radiology - Category: Radiology Source Type: research
Publication date: Available online 4 August 2020Source: Pathology - Research and PracticeAuthor(s): Guocheng Huang, Huijuan Li, Jingyao Wang, Xiqi Peng, Kaihao Liu, Liwen Zhao, Chunduo Zhang, Xuan Chen, Yongqing Lai, Liangchao Ni
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 4 August 2020Source: Pathology - Research and PracticeAuthor(s): Chenghao Lu, Zheyu Yang, Dingye Yu, Jianwei Lin, Wei Cai
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Even though New York Oncology Hematology is working to help patients understand that medical offices are safe, the practice has seen a drop in the number of people getting regular cancer screenings. And that could have negative impacts on long-term care and the economy.
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news
We describe the role of dosimetry in redifferentiation and subsequent I-131 therapy in RAI-R thyroid cancer, explain different dosimetry approaches and discuss limitations and considerations in the field. PMID: 32744039 [PubMed - in process]
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
Publication date: Available online 3 August 2020Source: Gynecologic Oncology ReportsAuthor(s): Tyler J. Woodard, Benjamin Margolis, Sarah Lee, Ghadir Salame
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
Publication date: Available online 3 August 2020Source: Gynecologic Oncology ReportsAuthor(s): Kevin M. Kremer, Jessica Lee, Matthew J. Carlson, Salvatore J. Lococo, David S. Miller, Jayanthi S. Lea
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
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