Prognostic Role of Neutrophil/Lymphocyte Ratio in Resected Gastric Cancer: A Systematic Review and Meta-analysis
High levels of inflammatory markers and the neutrophil-lymphocyte ratio appear to be associated with worse overall survival in solid tumors. However, few studies have analyzed the role of the neutrophil-lymphocyte ratio in gastric cancer patients scheduled to undergo curative resection. In the present study, a systematic review and meta-analysis was performed to analyze the relationship between the neutrophil-lymphocyte ratio and overall survival in patients with gastric cancer submitted to curative resection and to identify the clinicopathological features (age, gender, tumor depth, nodal involvement and tumor differentia...
Source: Clinics - June 18, 2018 Category: General Medicine Source Type: research

The influence of inspiratory muscle training combined with the Pilates method on lung function in elderly women: A randomized controlled trial
OBJECTIVE: Aging is progressive, and its effects on the respiratory system include changes in the composition of the connective tissues of the lung that influence thoracic and lung compliance. The Powerbreathe ® K5 is a device used for inspiratory muscle training with resistance adapted to the level of the inspiratory muscles to be trained. The Pilates method promotes muscle rebalancing exercises that emphasize the powerhouse. The aim of this study was to evaluate the influence of inspiratory muscle trai ning combined with the Pilates method on lung function in elderly women. METHODS: The participants were aged sixty y...
Source: Clinics - June 18, 2018 Category: General Medicine Source Type: research

Outcomes analysis of breast reduction in Brazilian women using the BREAST-Q® questionnaire: a cross-sectional controlled study
CONCLUSION: These results suggest that patients submitted to reduction mammoplasty are satisfied with the outcomes and present better quality of life scores compared with women with breast hypertrophy. (Source: Clinics)
Source: Clinics - June 18, 2018 Category: General Medicine Source Type: research

Evaluation of systemic inflammation in patients being weaned from mechanical ventilation
CONCLUSIONS: C-reactive protein is increased in patients who fail the spontaneous ventilation test, and increased ILs are associated with a greater prevalence of failure in this process; the rapid shallow breathing index may not be effective in patients who present systemic inflammation. (Source: Clinics)
Source: Clinics - June 18, 2018 Category: General Medicine Source Type: research

Study on the Correlation between Barium Radiography and Pulmonary Infection rate in the Evaluation of Swallowing Function
OBJECTIVES: To compare the results respectively obtained from the utilization of 60% barium sulfate suspension and Iohexol as contrast agents for videofluoroscopic swallowing studies and the relationship between the clinical application of the two kinds of contrast agents and the incidence of pneumonia. METHODS: Sixty cases of stroke patients with dysphagia were selected in rehabilitation department of our hospital, and the gender, age, position of the disease, and stroke nature between groups had no significant difference. Among which, 30 patients who were administered 350 mgI/ml Iohexol, and the other 30 patients with 60...
Source: Clinics - June 18, 2018 Category: General Medicine Source Type: research

Collagen I and III in women with diastasis recti
OBJECTIVES: Interest in elucidating the etiology of hernias has encouraged countless studies of musculoaponeurotic structures in individuals with and without hernias. Studies of hernia patients have firmly demonstrated a correlation between hernias and collagen alterations in their fascia. Diastasis recti is an increased width of the abdominal midline that is exclusively composed of interlacing aponeurotic expansions of the anterolateral abdominal muscles. The condition is common among women undergoing abdominoplasty, and many factors, not only mechanical, play a role. The goal of this study is to evaluate and compare coll...
Source: Clinics - June 7, 2018 Category: General Medicine Source Type: research

Performance of the 13C-urea breath test for the diagnosis of H. pylori infection using a substrate synthesized in Brazil: A preliminary study
CONCLUSIONS: Similar performance i n the diagnosis of Helicobacter pylori infection was demonstrated when using the 13C-urea breath test with the Brazilian 13C-urea substrate and the test with the substrate produced abroad. This validation represents an important step toward increasing the availability of the 13C-urea breath test thr oughout the country, which will have a positive influence on the management of Helicobacter pylori infection. (Source: Clinics)
Source: Clinics - June 7, 2018 Category: General Medicine Source Type: research

Malignancy rates for Bethesda III subcategories in thyroid fine needle aspiration biopsy (FNAB)
The objective of the present study was to evaluate the differences in the malignancy rates among Bethesda III subcategories. METHODS: Data from 1,479 patients who had thyroid surgery were reviewed. In total, 1,093 patients (89.6% female, mean age 52.7 (13-89) years) were included, and 386 patients were excluded. FNAB results (based on Bethesda Class) and histopathological results (benign or malignant) for coincident areas were collected. Bethesda III patients were subcategorized according to cytopathological characteristics (FLUS: follicular lesion of undetermined significance, Bethesda IIIA; AUS: atypia of undetermined si...
Source: Clinics - May 28, 2018 Category: General Medicine Source Type: research

Relationship between circulating VCAM-1, ICAM-1, E-selectin and MMP9 and the extent of coronary lesions
OBJECTIVES: Inflammatory molecules play a role in the development of atherosclerosis, which is the primary origin of cardiovascular disorders. However, to the best of our knowledge, no study has attempted to investigate the relationship between these circulating molecules and the prediction of cardiovascular risk. The present study aimed to investigate the relationships of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, E-selectin and matrix metalloproteinase 9 serum concentrations with the extent of coronary lesions. METHODS: Seventy-four individuals who were undergoing coronary angiography for the f...
Source: Clinics - May 28, 2018 Category: General Medicine Source Type: research

Liver biopsy may facilitate pancreatic graft evaluation: Positive association between liver steatosis and pancreatic graft adipose infiltration
OBJECTIVES: The number of pancreatic transplants has decreased in recent years. Pancreatic grafts have been underutilized compared to other solid grafts. One cause of discard is the macroscopic appearance of the pancreas, especially the presence of fatty infiltration. The current research is aimed at understanding any graft-related association between fatty tissue infiltration of the pancreas and liver steatosis. METHODS: From August 2013 to August 2014, a prospective cross-sectional clinical study using data from 54 multiple deceased donor organs was performed. RESULTS: Micro- and macroscopic liver steatosis were signific...
Source: Clinics - May 28, 2018 Category: General Medicine Source Type: research

Evaluation Instruments for Quality of Life Related to Melasma: An Integrative Review
The aim of this study was to analyze scientific production concerning the validation and cultural adaptation of quality of life evaluation instruments for patients with melasma and to offer a critical reflection on these methods. A literature review was performed based on a search of the Web of Science, Bireme, PubMed, Elsevier Scopus, and Google Scholar databases. All published articles from indexed periodicals in these electronic databases up to December 2015 were included. Eight articles were identified, of which only one (12.5%) referred to the development and validation of a specific instrument for evaluation of the q...
Source: Clinics - May 22, 2018 Category: General Medicine Source Type: research

Resting spontaneous baroreflex sensitivity and cardiac autonomic control in anabolic androgenic steroid users
CONCLUSIONS: Our results provide evidence for lower baroreflex sensitivity and sympathovagal imbalance in anabolic androgenic steroid users. Moreover, anabolic androgenic steroid users showed arterial stiffness. Together, these alterations might be the mechanisms triggering the increased blood pressure in this population. (Source: Clinics)
Source: Clinics - May 22, 2018 Category: General Medicine Source Type: research

Unilateral spatial neglect in the acute phase of ischemic stroke can predict long-term disability and functional capacity
CONCLUSION: The severity of unilateral spatial neglect in acute stroke worsens the degree of long-term disability and functional independence. (Source: Clinics)
Source: Clinics - May 22, 2018 Category: General Medicine Source Type: research

Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features (NIFTP): Achieving Better Agreement By Refining Diagnostic Criteria
(Source: Clinics)
Source: Clinics - May 22, 2018 Category: General Medicine Source Type: research

Specific questionnaire detects a high incidence of intra-operative hypersensitivity reactions
CONCLUSIONS: The majority of patients had hypersensitivity reactions grad e I reactions; however, the incidence of intra-operative anaphylaxis was higher than that previously reported in the literature. Patients with ASA 3 had more severe anaphylaxis; however, the use of epinephrine was not prescribed in all of these cases. Allergists and anesthesiologists should implemen t preventive measures to reduce the occurrence of anaphylaxis. (Source: Clinics)
Source: Clinics - May 17, 2018 Category: General Medicine Source Type: research

Use of direct oral anticoagulants for chronic thromboembolic pulmonary hypertension
CONCLUSIONS: Although direct oral anticoagulants appear to be a safe and effective alternative for treating chronic thromboembolic pulmonary hypertension, larger studies are needed to support their routine use. (Source: Clinics)
Source: Clinics - May 17, 2018 Category: General Medicine Source Type: research

Improving the Management of Hereditary Angioedema
(Source: Clinics)
Source: Clinics - May 17, 2018 Category: General Medicine Source Type: research

Brazilian Guidelines for Hereditary Angioedema Management - 2017 Update Part 1: Definition, Classification and Diagnosis
Hereditary angioedema is an autosomal dominant disease characterized by recurrent angioedema attacks with the involvement of multiple organs. The disease is unknown to many health professionals and is therefore underdiagnosed. Patients who are not adequately diagnosed and treated have an estimated mortality rate ranging from 25% to 40% due to asphyxiation by laryngeal angioedema. Intestinal angioedema is another important and incapacitating presentation that may be the main or only manifestation during an attack. In this article, a group of experts from the “ Associa ção Brasileira de Alergia e Imunolog...
Source: Clinics - May 3, 2018 Category: General Medicine Source Type: research

Stroke risk among patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis
In this study, we conducted a systematic review and meta-analysis to assess stroke risk among chronic obstructive pulmonary disease patients. PubMed, EMBASE, and the Cochrane Library were systematically searched from database inception until December 31, 2016 to identify longitudinal observational studies that investigated the association between chronic obstructive pulmonary disease and stroke. Stroke risk was quantified by overall and subgroup analyses, and a pooled hazard ratio was calculated. Study quality was evaluated using the Newcastle-Ottawa Scale. Publication bias was assessed using Begg ’ s rank correlatio...
Source: Clinics - May 3, 2018 Category: General Medicine Source Type: research

En bloc vertebrectomy for the treatment of spinal lesions. Five years of experience in a single institution: a case series
CONCLUSION: This study demonstrates and reinforces the reproducibility of the en bloc vertebrectomy technique described by Tomita et al. (Source: Clinics)
Source: Clinics - May 3, 2018 Category: General Medicine Source Type: research

Low estrogen doses normalize testosterone and estradiol levels to the female range in transgender women
CONCLUSION: In our sample of transgender women, lower estrogen doses than those usually prescribed for these subjects were able to adjust the testosterone and estradiol levels to the physiological female range, thus avoiding high estrogen doses and their multiple associated side effects. (Source: Clinics)
Source: Clinics - May 3, 2018 Category: General Medicine Source Type: research

Early psychiatric morbidity in a Brazilian sample of acute ischemic stroke patients
CONCLUSION: Psychiatric comorbidity should be evaluated as part of the rehabilitation of stroke patients and should be carefully examined by physicians. (Source: Clinics)
Source: Clinics - May 3, 2018 Category: General Medicine Source Type: research

Impact of discharge medication counseling in the cardiology unit of a tertiary hospital in Brazil: A randomized controlled trial
This study aimed to evaluate the impact of pharmacist-provided discharge counseling on mortality rate, hospital readmissions, emergency department visits, and medication adherence at 30 days post discharge. METHODS: This randomized controlled trial was approved by the local ethics committee and included patients aged 18 years or older admitted to the cardiology ward of a Brazilian tertiary hospital. The intervention group received a pharmacist-led medication counseling session at discharge and a telephone follow-up three and 15 days after discharge. The outcomes included the number of deaths, hospital readmissions, emergen...
Source: Clinics - April 26, 2018 Category: General Medicine Source Type: research

Post-Traumatic Stress Disorder and severe maternal morbidity: is there an association?
CONCLUSIONS: A severe maternal morbidity episode is not associated with Post-Traumatic Stress Disorder symptoms within five years of the severe maternal morbidity event and birth. However, a more advanced maternal age and primiparity increased the risk of Post-Traumatic Stress Disorder. This does not imply that women who had experienced a severe maternal morbidity event did not suffer or need differentiated care. (Source: Clinics)
Source: Clinics - April 26, 2018 Category: General Medicine Source Type: research

Type II and III Selective Fetal Growth Restriction: Perinatal Outcomes of Expectant Management and Laser Ablation of Placental Vessels
CONCLUSION: LAPV in type II and III sFGR twins with arAWDV in the smaller fetus seems to yield outcomes similar to those of less severe cases that received expectant management. (Source: Clinics)
Source: Clinics - April 26, 2018 Category: General Medicine Source Type: research

Analysis of the Role of Physicians in the Cessation of Cigarette Smoking Based on Medical Specialization
OBJECTIVE: Physicians do not adequately use their unique professional privilege to prevent patients from smoking. The aim of this study was to investigate the type and extent of advice given to patients by physicians of different medical specialties regarding smoking cessation. METHODS: In total, 317 volunteer physicians were included in this study. The participants rated their attitudes toward the smoking habits of their patients by completing a questionnaire. The approaches used to address the smoking habits of patients significantly differed among physicians working at polyclinics, clinics and emergency service departments (p
Source: Clinics - April 19, 2018 Category: General Medicine Source Type: research

Neuroprotective effects of erythropoietin on rat retinas subjected to oligemia
CONCLUSIONS: The number of partially preserved retinal ganglion cells in the erythropoietin-treated group suggests that erythropoietin exerts a neuroprotective effect on oligemic/ischemic retinas. This effect could be re lated to the down-modulation of glial reactivity, usually observed in hypoxic conditions, clinically observed during glaucoma or retinal artery occlusion conditions. Therefore, glial reactivity may enhance neurodegeneration in hypoxic conditions, like normal-tension glaucoma and retinal ischemia, an d erythropoietin is thus a candidate to be clinically applied after the detection of decreased retinal blood...
Source: Clinics - April 19, 2018 Category: General Medicine Source Type: research

Cardiovascular abnormalities in patients with oral cleft: a clinical-electrocardiographic-echocardiographic study
CONCLUSION: The finding of a family risk of developing plurimetabolic syndrome and a diagnosis of rheumatic heart disease indicates that patients with oral clefts may be more prone to developing acquired heart disease. Thus, our findings highlight the importance of anamnesis and methodological triangulation (clinical-electrocardiographic-echocardiographic) in the investigation of patients with oral clefts and emphasize that cardiological follow-up to evaluate acquired and/or rhythm heart diseases is necessary. This strategy permits comorbidity prevention and individualized planned treatment. (Source: Clinics)
Source: Clinics - April 19, 2018 Category: General Medicine Source Type: research

Micromass cultures are effective for differentiation of human amniotic fluid stem cells into chondrocytes
CONCLUSION: We demonstrate that stem cells from human amniotic fluid are a suitable source for chondrogenesis when cultured in a micromass system. amniotic fluid mesenchymal stromal stem cells are an extremely viable source for clinical applications, and our results suggest the possibility of using human amniotic fluid as a source of mesenchymal stem cells. (Source: Clinics)
Source: Clinics - April 5, 2018 Category: General Medicine Source Type: research

Difficulties in the diagnosis and treatment of rare diseases according to the perceptions of patients, relatives and health care professionals
CONCLUSIONS: The complex set of health system requirements necessary to support the care of patients with rare diseases represents an obstacle to successfully meeting the needs of patients and their families. Therefore, it is important to develop specific public policies to create referral services, guarantee access to appropriate therapeutic modalities and incorporate technologies that promote research for developing new, affordable therapies. (Source: Clinics)
Source: Clinics - April 5, 2018 Category: General Medicine Source Type: research

ERRATUM: Systematic review and meta-analysis of the efficacy and safety of amfepramone and mazindol as a monotherapy for the treatment of obese or overweight patients
Our aim in this study was to compare the efficiency of 25G versus 22G needles in diagnosing solid pancreatic lesions by EUS-FNA. We performed a systematic review and meta-analysis. Studies were identified in five databases using an extensive search strategy. Only randomized trials comparing 22G and 25G needles were included. The results were analyzed by fixed and random effects. A total of 504 studies were found in the search, among which 4 randomized studies were selected for inclusion in the analysis. A total of 462 patients were evaluated (233: 25G needle/229: 22G needle). The diagnostic sensitivity was 93% for the 25G ...
Source: Clinics - March 15, 2018 Category: General Medicine Source Type: research

Standardization of a spinal cord lesion model and neurologic evaluation using mice
CONCLUSION: This spinal cord lesion mouse model proved to be effective and reliable with exception of lesions caused by a 10-g drop from 50 mm, which resulted in unacceptable mortality. The Basso, Beattie, Bresnahan Locomotor Rating Scale and Basso Mouse Scale are the most reliable functional assessments, and but the horizontal ladder test is not recommended. (Source: Clinics)
Source: Clinics - March 15, 2018 Category: General Medicine Source Type: research

Improvement in lung function and functional capacity in morbidly obese women subjected to bariatric surgery
CONCLUSION: The present data suggest that changes in body composition and anthropometric variables exerted a direct influence on functional capacity and lung function in the women analyzed but exerted no influence on sedentarism, even after accentuated weight loss following bariatric surgery. (Source: Clinics)
Source: Clinics - March 15, 2018 Category: General Medicine Source Type: research

Preoperative treatment with 5α-reductase inhibitors and the risk of hemorrhagic events in patients undergoing transurethral resection of the prostate – A population-based cohort study
OBJECTIVES: To assess the associations between preoperative treatment with 5-alpha reductase inhibitors and the risks of blood transfusion during transurethral resection of the prostate and blood clot evacuation or emergency department visits for hematuria within 1 month after surgery. METHODS: We used data from the Taiwan National Health Insurance Research Database in this population-based cohort study. A total of 3,126 patients who underwent first-time transurethral resection of the prostate from 2004 to 2013 were identified. Adjusted odds ratios estimated by multiple logistic regression models were used to assess the in...
Source: Clinics - March 12, 2018 Category: General Medicine Source Type: research

Voice deviation, dysphonia risk screening and quality of life in individuals with various laryngeal diagnoses
CONCLUSION: A predominance of adult women, organic dysphonia, moderate voice deviation, high dysphonia risk, and low to moderate quality of life impact characterized our sample. There were correlations between the scores of each of the three questionnaires and the degree of voice deviation. It should be noted that the DRSP monitored the degree of dysphonia severity, which reinforces its applicability for patients with different laryngeal diagnoses. (Source: Clinics)
Source: Clinics - March 12, 2018 Category: General Medicine Source Type: research

Burkholderia cepacia, cystic fibrosis and outcomes following lung transplantation: experiences from a single center in Brazil
CONCLUSION: The results of our study suggest that colonization by B. cepacia complex and even B. cenocepacia in patients with cystic fibrosis should not be considered an absolute contraindication to lung transplantation in Brazilian centers. (Source: Clinics)
Source: Clinics - March 12, 2018 Category: General Medicine Source Type: research

Granulocyte Colony-Stimulating Factor Combined with Methylprednisolone Improves Functional Outcomes in Rats with Experimental Acute Spinal Cord Injury
OBJECTIVES: To evaluate the effects of combined treatment with granulocyte colony-stimulating factor (G-CSF) and methylprednisolone in rats subjected to experimental spinal cord injury. METHODS: Forty Wistar rats received a moderate spinal cord injury and were divided into four groups: control (no treatment); G-CSF (G-CSF at the time of injury and daily over the next five days); methylprednisolone (methylprednisolone for 24 h); and G-CSF/Methylprednisolone (methylprednisolone for 24 h and G-CSF at the time of injury and daily over the next five days). Functional evaluation was performed using the Basso, Beattie and Bresnah...
Source: Clinics - February 19, 2018 Category: General Medicine Source Type: research

Preventable adverse drug events in critically ill HIV patients: Is the detection of potential drug-drug interactions a useful tool?
CONCLUSIONS: The approach used in this study allowed for the detection of adverse drug events related to 9% of the potential drug-drug interactions that were identified; these adverse drug events affected 26% of the study population. With the monitoring of adverse drug events based on prescriptions, a combination of the evaluation of potential drug-drug interactions by clinical pharmacy services and the monitoring of critically ill patients is an effective strategy that can be used as a complementary tool for safety assessments and the prevention of adverse drug events. (Source: Clinics)
Source: Clinics - February 19, 2018 Category: General Medicine Source Type: research

Monitoring auditory cortical plasticity in hearing aid users with long latency auditory evoked potentials: a longitudinal study
CONCLUSIONS: Alterations in the central auditory pathways can be identified using P1-N1 and P2-N2 amplitude components, and the presence of these components increases after a short period of auditory stimulation (hearing aid use). These findings emphasize the importance of using these amplitude components to monitor the neuroplasticity of the central auditory nervous system in hearing aid users. (Source: Clinics)
Source: Clinics - February 19, 2018 Category: General Medicine Source Type: research

A comparison of the efficiency of 22G versus 25G needles in EUS-FNA for solid pancreatic mass assessment: A systematic review and meta-analysis
Our aim in this study was to compare the efficiency of 25G versus 22G needles in diagnosing solid pancreatic lesions by EUS-FNA. We performed a systematic review and meta-analysis. Studies were identified in five databases using an extensive search strategy. Only randomized trials comparing 22G and 25G needles were included. The results were analyzed by fixed and random effects. A total of 504 studies were found in the search, among which 4 randomized studies were selected for inclusion in the analysis. A total of 462 patients were evaluated (233: 25G needle/229: 22G needle). The diagnostic sensitivity was 93% for the 25G ...
Source: Clinics - February 15, 2018 Category: General Medicine Source Type: research

Application of a pharmacokinetics-pharmacodynamics approach to the free propofol plasma levels during coronary artery bypass grafting surgery with hypothermic cardiopulmonary bypass
CONCLUSIONS: The orotracheal intubation time was significantly longer in the hypothermic on-pump group than in the off-pump group. Additionally, residual hypnosis was identified through the pharmacokinetics-pharmacodynamics approach based on decreases in drug plasma protein binding in the hypothermic on-pump group, which could explain the increased hypnosis observed with this drug in this group of patients. (Source: Clinics)
Source: Clinics - February 15, 2018 Category: General Medicine Source Type: research

The Association of Vitamin D Levels and the Frailty Phenotype Among Non-geriatric Dialysis Patients: A Cross-sectional Study
CONCLUSIONS: Weakness and slowness are serious outcomes of both vitamin D deficiency and frailty, and vitamin D deficiency has been associated with increased risks of decreased physical activity, falls, fractures and death in postmenopausal women and older men. Although studies on frailty have focused on older adults, growing evidence indicates that the frailty phenotype is becoming a factor associated with poor health outcomes in non-geriatric populations with chronic disease. (Source: Clinics)
Source: Clinics - February 15, 2018 Category: General Medicine Source Type: research

Increase of 10% in the Rate of Adverse Drug Reactions for Each Drug Administered in Hospitalized Patients
CONCLUSIONS: Adverse drug reactions are frequent and potentially serious and should be better monitored in patients with chronic renal failure or prolonged hospitalization and especially in those on ‘ polypharmacy ’ regimens. The rational use of medications plays an important role in preventing adverse drug reactions. (Source: Clinics)
Source: Clinics - February 8, 2018 Category: General Medicine Source Type: research

Risk factors for the prognosis of pediatric medulloblastoma: a retrospective analysis of 40 cases
OBJECTIVES: To evaluate the influence of secondhand cigarette smoke exposure on longitudinal growth of the tibia of growing rats and some parameters of bone quality. METHODS: Forty female rats were randomly divided into four groups: control: rats were sham exposed; 30 days: rats were exposed to tobacco smoke for 30 days; 45 days: rats were exposed to tobacco smoke for 45 days; and 60 days: rats were exposed to tobacco smoke for 60 days. Blood samples were collected to evaluate the levels of cotinine and alkaline phosphatase. Both tibias were dissected and weighed; the lengths were measured, and the bones were then stored i...
Source: Clinics - January 9, 2018 Category: General Medicine Source Type: research

Second hand tobacco smoke adversely affects the bone of immature rats
OBJECTIVES: To evaluate the influence of secondhand cigarette smoke exposure on longitudinal growth of the tibia of growing rats and some parameters of bone quality. METHODS: Forty female rats were randomly divided into four groups: control: rats were sham exposed; 30 days: rats were exposed to tobacco smoke for 30 days; 45 days: rats were exposed to tobacco smoke for 45 days; and 60 days: rats were exposed to tobacco smoke for 60 days. Blood samples were collected to evaluate the levels of cotinine and alkaline phosphatase. Both tibias were dissected and weighed; the lengths were measured, and the bones were then stored i...
Source: Clinics - January 9, 2018 Category: General Medicine Source Type: research

Experimental implantation of an arterial substitute made of silicone reinforced with polyester fabric in rabbits
CONCLUSIONS: We concluded that polydimethylsiloxane has limited potential as an alternative material for small vascular prostheses. (Source: Clinics)
Source: Clinics - January 9, 2018 Category: General Medicine Source Type: research

Evaluation of the efficacy and safety of endovascular management for transplant renal artery stenosis
CONCLUSION: Angioplasty with stent placement for the treatment of transplant renal artery stenosis is a safe and effective technique with good results in both the short and long term. (Source: Clinics)
Source: Clinics - January 9, 2018 Category: General Medicine Source Type: research

Characteristics and Outcomes of Intensive Care Unit Survivors: Experience of a Multidisciplinary Outpatient Clinic in a Teaching Hospital
CONCLUSIONS: A significant number of intensive care unit survivors evaluated 3 months after discharge had psychological, respiratory, motor, and socioeconomic problems; these findings highlight that strategies aimed to assist critically ill patients should be extended to the post-hospitalization period and that this problem is particularly important in low-income populations. (Source: Clinics)
Source: Clinics - January 9, 2018 Category: General Medicine Source Type: research

Pain and quality of life in breast cancer patients
OBJECTIVE: To evaluate the influence of pain on quality of life in breast cancer patients. METHODS: A cross-sectional study of 400 patients, including 118 without metastasis, 160 with loco-regional metastasis and 122 with distant metastasis. The instruments used were the European Organization for Research and Treatment for Cancer Quality of Life Questionnaire-Core 30 and the Breast Cancer-specific 23 and short McGill Pain Questionnaire. RESULTS: In total, 71.7% of patients reported pain. The most frequent sensory descriptor used by patients was ‘ jumping. ’ In the evaluative dimension, the main descriptor chose...
Source: Clinics - January 9, 2018 Category: General Medicine Source Type: research

Microcirculation improvement after short-term infusion of vasopressin in septic shock is dependent on noradrenaline
CONCLUSIONS: In patients with septic shock for no longer than 48 h, administration of vasopressin is likely to result in an improvement in microcirculation when the baseline noradrenaline dose is higher than 0.38 mcg/kg/min. (Source: Clinics)
Source: Clinics - January 9, 2018 Category: General Medicine Source Type: research