Short-term survival in extensive craniofacial resections
CONCLUSIONS: In our study, factors related to tumor extension were associated with a higher risk of perioperative death. (Source: Clinics)
Source: Clinics - May 21, 2021 Category: General Medicine Source Type: research

Multilayer stents affect the final diameter of aortic aneurysms and maintain renal artery patency for a short time in a swine experimental model
CONCLUSION: The MFMSs remained patent and did not obstruct the renal arteries within 4 weeks. In the stent group, the device was also associated with a significant decrease in aneurysmal sac diameter and a large proportion (albeit non-significant) of aneurysmal sac thrombosis. (Source: Clinics)
Source: Clinics - May 21, 2021 Category: General Medicine Source Type: research

Risk Factors Associated with Postoperative Infection in Cancer Patients Undergoing Spine Surgery
CONCLUSIONS: Surgical time greater than 4 hours, surgical instrumented levels greater than 6, and an Eastern Cooperative Oncology Group of 3 or 4 were associated with an increased risk of postoperative infection, but these factors did not lead to an increase in mortality during hospitalization. (Source: Clinics)
Source: Clinics - May 17, 2021 Category: General Medicine Source Type: research

Efficacy and safety of umbilical cord mesenchymal stem cells for the treatment of patients with COVID-19
CONCLUSION: Intravenous infusion of MSCs in patients with COVID-19 was effective and well tolerated. Further studies involving a large cohort or randomized controlled trials are warranted. (Source: Clinics)
Source: Clinics - May 17, 2021 Category: General Medicine Source Type: research

Claudin-1 and Claudin-3 as Molecular Regulators of Myelination in Leukoaraiosis Patients
CONCLUSION: Our data has demonstrated that the abnormal expression of claudin-1 and claudin-3 regulates the pathological progression of leukoaraiosis by governing the viability and myelination of oligodendrocytes. These findings provide novel insights into the regulatory mechanisms underlying the roles of claudin-1 and claudin-3 in leukoaraiosis. (Source: Clinics)
Source: Clinics - May 17, 2021 Category: General Medicine Source Type: research

Melatonin can be, more effective than N-acetylcysteine, protecting acute lung injury induced by intestinal ischemia-reperfusion in rat model
CONCLUSION: Both agents individually provided tissue protective effect against intestinal IR-induced lung injury, but melatonin was m ore effective in ameliorating the parameters analyzed in this study. (Source: Clinics)
Source: Clinics - May 5, 2021 Category: General Medicine Source Type: research

A Modified Flexor Tendon Suture Technique Combining Kessler and Loop Lock Flexor Tendon Sutures
CONCLUSION: As opposed to the traditional MK+P method, the SK+P method was improved and exhibited better biomechanical properties, which may facilitate early mobilization after the repair. (Source: Clinics)
Source: Clinics - May 5, 2021 Category: General Medicine Source Type: research

Overexpression of serum extracellular vesicle microRNA-215-5p is associated with early tumor recurrence and poor prognosis of gastric cancer
CONCLUSIONS: Serum EV-miR-215-5p might be a novel biomarker for predicting ETR and prognosis of GC. (Source: Clinics)
Source: Clinics - May 5, 2021 Category: General Medicine Source Type: research

A randomized controlled study on an integrated approach to prevent and treat re-adhesion after transcervical resection of moderate-to-severe intrauterine adhesions
CONCLUSIONS: After surgical management of IUA, the integrated treatment combining a uterus stent placement and artificial cycle with Danshen injection and oral Chinese medicine can improve the condition of menstruation, and prevent and treat recurrence of IUA. (Source: Clinics)
Source: Clinics - May 5, 2021 Category: General Medicine Source Type: research

Guselkumab: widened action in psoriatic disease
(Source: Clinics)
Source: Clinics - May 5, 2021 Category: General Medicine Source Type: research

Double-Needle Arthrocentesis with Viscosupplementation in Patients with Temporomandibular Joint Disc Displacement without Reduction
CONCLUSION: Patients with DDwoR undergoing arthrocentesis combined with hyaluronic acid injection showed significant improvement in the perceived pain and maximum mouth opening in the mid-term follow-up periods. (Source: Clinics)
Source: Clinics - April 26, 2021 Category: General Medicine Source Type: research

Estradiol prevented intestinal ischemia and reperfusion-induced changes in intestinal permeability and motility in male rats
CONCLUSION: Collectively, our findings indicate that estradiol treatment can modulate the deleterious intestinal effects of I/R injury. Thus, estradiol mediates the improvement in gut barrier functions and prevents intestinal dysfunction, which may reduce the systemic inflammatory response. (Source: Clinics)
Source: Clinics - April 26, 2021 Category: General Medicine Source Type: research

Combined use of immunohistochemical markers of basal and luminal subtypes in urothelial carcinoma of the bladder: Association with clinicopathological features and outcomes
CONCLUSION: This study demonstrates that these three routinely used immunohistochemical markers could be used to stratify urothelial carcinomas of the bladder into basal and luminal subtypes, which are associated with several differences in clinicopathological features. (Source: Clinics)
Source: Clinics - April 26, 2021 Category: General Medicine Source Type: research

Role of cancer ratio and other new parameters in the differential diagnosis of malignant pleural effusion
CONCLUSIONS: The best parameter for diagnosing MPE was different for patients aged ≤ 50 years and>50 years. For patients aged>50 years, CR plus was a good parameter for the differential diagnosis of MPE. For patients aged ≤ 50 years, pfADA was better. (Source: Clinics)
Source: Clinics - April 26, 2021 Category: General Medicine Source Type: research

Bodyweight distribution between limbs, muscle strength, and proprioception in traumatic transtibial amputees: a cross-sectional study
CONCLUSIONS: The asymmetric bodyweight distribution in the transtibial amputees was not accompanied by a reduction in knee proprioception. There was significant weakness in the amputated limb, which could be a potential issue when designing rehabilitation programs. (Source: Clinics)
Source: Clinics - April 26, 2021 Category: General Medicine Source Type: research