A Case for Alpha-Lipoic Acid as an Alternative Treatment for Diabetic Polyneuropathy.

CONCLUSIONS: ALA demonstrates effectiveness in treating DPN through multiple mechanisms to modulate pathophysiology and control symptoms. In addition, ALA exhibits activity in weight management and insulin sensitivity. The use of ALA for DPN in the US is worth considering because commonly prescribed medications have unclear mechanisms, more pronounced adverse effects, and are more expensive than ALA.  Further research needs to be conducted to assess long-term efficacy of ALA in US patients. PMID: 30139425 [PubMed - in process]
Source: J Pharm Pharm Sci - Category: Drugs & Pharmacology Authors: Tags: J Pharm Pharm Sci Source Type: research