Two Types of Gastric Cancer Caused by the Same Underlying Condition
Question: A 62-year-old female with Lynch syndrome had a CT scan performed after a fall, which incidentally discovered multiple polypoid lesions within the stomach. The patient had a history of endometrial adenocarcinoma at age 50, as well as a family history significant for a sister with colon cancer at age 59. Based on this cancer history she had recently undergone genetic testing which revealed a pathogenic PMS2 mutation, consistent with Lynch syndrome. The patient was asymptomatic from a gastrointestinal perspective without any nausea, vomiting, abdominal pain, diarrhea, rectal bleeding, or unintentional weight loss.
This study aims to examine the effectiveness of the postural treatment of the Mézières method on elite rhythmic gymnastics athletes with low back pain. DESIGN: Double-blind, randomized, controlled trial. SETTING: The sports hall of "Puente Tocinos," Murcia, Spain. PARTICIPANTS: Ninety gymnastics athletes were randomized into 2 parallel groups (intervention: n = 39; control: n = 51), of whom 98.9% were women (women = 89; man = 1). INTERVENTION: The Mézières method postural therapy was implemented. It lasted about 60 minutes in repeated sessions of 2 to 3 meetings per wee...
Authors: Fyock M, Cortes N, Hulse A, Martin J Abstract Clinical Scenario: Patellofemoral pain (PFP) is a common knee injury in recreational adult runners, possibly caused by faulty mechanics. One possible approach to reduce this pain is to retrain the runner's gait. Current research suggests that no definitive gold standard treatment for PFP exists. Gait retraining utilizing visual feedback may reduce PFP in both the short and long term. Clinical Question: In adult runners diagnosed with PFP, does gait retraining with real-time visual feedback lead to a decrease in pain? Summary of Key Findings: A literature search...
Conclusion: HTX-019 administered by 2-minute injection has a tolerable safety profile in patients with cancer, representing a viable method of HTX-019 administration for CINV prevention. PMID: 31709853 [PubMed - as supplied by publisher]
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM) Issue: Ahead of print
CONCLUSIONS: EGFR expression is significantly higher in HPV positive IP. Stathmin is expressed by all IP tumour cells. Stathmin was also associated with dysplasia and a trend towards a correlation between stathmin positivity and recurrence was found. Stathmin and EGFR might therefore be considered therapeutic targets. PMID: 31710049 [PubMed - as supplied by publisher]
Authors: Wu Z, Ma Y PMID: 31707863 [PubMed - as supplied by publisher]
Authors: Kunutsor SK, Mäkikallio TH, Laukkanen JA PMID: 31707862 [PubMed - as supplied by publisher]
Authors: Elfiky TA, Patil ND, Allam Y, Ragab R Abstract Study Design: A retrospective radiographic analysis. Purpose: The aim of the current study is to assess endplate changes after the use of polyetheretherketone (PEEK) cages in posterior lumbar interbody fusion (PLIF). Overview of Literature: A few recent reports had revealed endplate abnormalities due to PEEK cages, which may lead to nonunions. Methods: A retrospective computed tomography (CT)-based analysis of the endplate cavities and fusion status following PLIFs with PEEK cages was conducted by two independent observers. The term "cavity&qu...
Conclusions: the early use of IVIG could contribute to an improvement and/or stabilization of visual symptoms in this patient group due to its rapid effect and lower profile of adverse effects when administered with chemotherapy. PMID: 31710513 [PubMed - as supplied by publisher]
Authors: Ahmad TR, Doan T, Gonzales JA, Acharya NR, Tsui E PMID: 31710511 [PubMed - as supplied by publisher]