Two Types of Gastric Cancer Caused by the Same Underlying  Condition

Question: A 62-year-old female with Lynch syndrome had a CT scan performed after a fall, which incidentally discovered multiple polypoid lesions within the stomach. The patient had a history of endometrial adenocarcinoma at age 50, as well as a family history significant for a sister with colon cancer at age 59. Based on this cancer history she had recently undergone genetic testing which revealed a pathogenic PMS2 mutation, consistent with Lynch syndrome. The patient was asymptomatic from a gastrointestinal perspective without any nausea, vomiting, abdominal pain, diarrhea, rectal bleeding, or unintentional weight loss.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Practical Teaching Cases Source Type: research