Log in to search using one of your social media accounts:

 

Cancer Risk Patterns in Lynch Syndrome Differ by Path_MMR Variants Cancer Risk Patterns in Lynch Syndrome Differ by Path_MMR Variants
Carriers of different path_MMR variants (Lynch syndrome) show different patterns of cancer risk and survival, according to findings from the Prospective Lynch Syndrome Database (PSLD).Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - August 11, 2017 Category: Pathology Tags: Hematology-Oncology News Source Type: news

Even Distant Relatives of Lynch Syndrome Patients Face Higher Cancer Risks Even Distant Relatives of Lynch Syndrome Patients Face Higher Cancer Risks
Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 8, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Do YOU have Lynch syndrome? Genetic condition is common cause of killer bowel cancer
LYNCH syndrome is a genetic condition which is the most common cause of hereditary bowel cancer. (Source: Daily Express - Health)
Source: Daily Express - Health - June 27, 2017 Category: Consumer Health News Source Type: news

Lynch Syndrome Mutations and Risk of Breast and Ovarian Cancer Lynch Syndrome Mutations and Risk of Breast and Ovarian Cancer
Although Lynch syndrome is thought to increase the risk of colorectal and/or uterine cancer, certain mutations may confer an increased risk of breast or ovarian cancer, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 2, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Increasing the age limit for Lynch syndrome genetic testing may save lives
(European Society of Human Genetics) Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5 percent of all colon cancers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 29, 2017 Category: Cancer & Oncology Source Type: news

NICE recommends wider use of tests to detect cancer-causing genetic condition
NICE has published diagnostics guidance recommending that everyone who is diagnosed with colorectal cancer should be tested for an inherited genetic condition called Lynch syndrome (LS). (Source: NHS Networks)
Source: NHS Networks - February 22, 2017 Category: UK Health Source Type: news

Understanding GP attitudes to cancer preventing drugs
A report from Cancer Research explores how much GPs know about two drugs that can reduce the risk of cancer – tamoxifen for women at high risk of breast cancer, and aspirin for people with Lynch Syndrome, a condition that increases the risk of several types of cancer. (Source: NHS Networks)
Source: NHS Networks - February 16, 2017 Category: UK Health Source Type: news

Lynch Syndrome –Associated Ovarian Cancer Presents Early, Has Good Prognosis
An analysis of Lynch syndrome –associated ovarian cancer found that the malignancy tends to present at an early stage and has a generally good prognosis. (Source: CancerNetwork)
Source: CancerNetwork - January 25, 2017 Category: Cancer & Oncology Authors: Dave Levitan Tags: Gynecologic Cancers News Ovarian Cancer Source Type: news

Multigene Testing a'Must' for Young Patients With CRC Multigene Testing a'Must' for Young Patients With CRC
Genetic testing for patients with colorectal cancer diagnosed at age younger than 50 years needs to go beyond Lynch syndrome.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - December 15, 2016 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Family History and Genomics as Tools for Cancer Prevention Family History and Genomics as Tools for Cancer Prevention
This brief examines the role of public health initiatives for cancer genomics at the federal, state, and community level, with a focus on hereditary breast and ovarian cancers and Lynch syndrome.Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 14, 2016 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

NICE recommends wider use of tests to detect cancer-causing genetic condition
In draft guidance published for consultation NICE has recommended that everyone who is diagnosed with colorectal cancer should be tested for an inherited genetic condition called Lynch syndrome (LS). (Source: NHS Networks)
Source: NHS Networks - October 30, 2016 Category: UK Health Source Type: news

Patients With Bowel Cancer'Not Being Tested for Lynch Syndrome'Patients With Bowel Cancer'Not Being Tested for Lynch Syndrome '
Almost one third of UK hospitals do not routinely test patients with bowel cancer younger than age 50 years for Lynch syndrome, despite it increasing the risk for cancer recurrence, survey results suggest.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 10, 2016 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Nearly a third of hospitals failing bowel cancer patients
Pathologists says hospitals must offer younger patients screening for Lynch syndrome Related items fromOnMedica Gene found to be linked to increased risk of recurrence in bowel cancer More than half of new bowel cancer screen test invitees fail to take up offer Meeting cancer promises and more – a new model for NHS diagnostics? New test prompts rise in bowel screening uptake Early stage bowel cancer more likely to be picked up by screening (Source: OnMedica Latest News)
Source: OnMedica Latest News - August 7, 2016 Category: UK Health Source Type: news

Target screening for Lynch syndrome saves costs
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - June 30, 2016 Category: Drugs & Pharmacology Source Type: news

Methylated DNA markers hold promise for Lynch syndrome
SAN DIEGO – It has been challenging to identify reliable biomarkers for Lynch syndrome colorectal neoplasms, but that may be about to change. Researchers have identified 10 discriminant methylated... (Source: Family Practice News)
Source: Family Practice News - May 23, 2016 Category: Primary Care Source Type: news

CRC Risk in African American Families With Lynch SyndromeCRC Risk in African American Families With Lynch Syndrome
Are African American families with Lynch syndrome at an increased risk for developing colorectal cancer and, if so, what exactly is the pathophysiology of disease in this group? Gastroenterology (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - May 18, 2016 Category: Pathology Tags: Gastroenterology Journal Article Source Type: news

Screening for Lynch Syndrome: An Audit and Cost AnalysisScreening for Lynch Syndrome: An Audit and Cost Analysis
This report assessed the potential financial impact of routinely screening colorectal cancer patients for Lynch syndrome. Could it save money in the long run? Journal of Clinical Pathology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 21, 2016 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Six Ways to Lower Your Risk for Colon Cancer
By Stacy Simon Colon cancer is one of the more common cancers in the US. About 1 in 20 Americans will develop colon cancer at some point during their lifetime. But there are things you can do to help lower your colon cancer risk. Here are 6 ways to help protect your colon health. Get screened for colon cancer. Screenings are tests that look for cancer before signs and symptoms develop. Colon screenings can often find growths called polyps that can be removed before they turn into cancer. These tests also can find colon cancer earlier, when treatments are more likely to be successful. The American Cancer Society recommend...
Source: American Cancer Society :: News and Features - March 7, 2016 Category: Cancer & Oncology Tags: Colon/Rectum Cancer Source Type: news

Signs and Symptoms of Colon Cancer
By Stacy Simon Many of the symptoms of colon cancer can also be caused by something that isn’t cancer, such as infection, hemorrhoids, irritable bowel syndrome, or inflammatory bowel disease. In most cases, people who have these symptoms do not have cancer. Still, if you have any of these problems, it is a sign that you should go to the doctor so the cause can be found and treated, if needed:A change in bowel habits, such as diarrhea, constipation, or narrowing of the stool, that lasts for more than a few daysA feeling that you need to have a bowel movement that is not relieved by doing soRectal bleedingDark stools, ...
Source: American Cancer Society :: News and Features - February 29, 2016 Category: Cancer & Oncology Tags: Colon/Rectum Cancer Prevention/Early Detection Source Type: news

Lynch Syndrome or Hereditary Nonpolyposis...
Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC) increases the risk of developing colon and other cancers. (Source: About.com Colon Cancer)
Source: About.com Colon Cancer - January 20, 2016 Category: Cancer & Oncology Authors: coloncancer.guide at about.com Tags: health Source Type: news

Guidelines Recommend that Patients with Colorectal Cancer Be Tested for Lynch Syndrome (FREE)
By Kelly Young Edited by André Sofair, MD, MPH, and William E. Chavey, MD, MS New guidelines from the American Gastroenterological Association advise physicians to test … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - September 11, 2015 Category: Primary Care Source Type: news

AGA recommends all patients with colorectal cancer get tested for Lynch syndrome
(American Gastroenterological Association) All colorectal cancer patients should undergo tumor testing to see if they carry Lynch syndrome, the most common inherited cause of colorectal cancer, according to a new guideline was published in Gastroenterology, the official journal of the American Gastroenterological Association. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 10, 2015 Category: Cancer & Oncology Source Type: news

Lynch Syndrome With MLH1 Mutations and Breast Cancer RiskLynch Syndrome With MLH1 Mutations and Breast Cancer Risk
Should breast cancer be included in the spectrum of cancers associated with Lynch syndrome and proven MMR mutations? Journal of Medical Genetics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 28, 2015 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

New strategy improves detection of genetic mutations in hereditary colorectal cancer
(Elsevier Health Sciences) The role that PMS2 genetic mutations play in Lynch syndrome has been underestimated in part due to technological limitations. A new study in the Journal of Molecular Diagnostics describes a multi-method strategy to overcome existing technological limitations by more accurately identifying PMS2 gene mutations, which will improve diagnosis and support appropriate genetic counseling and medical management. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 27, 2015 Category: Cancer & Oncology Source Type: news

Obesity-Cancer Link in Lynch Syndrome Quashed by AspirinObesity-Cancer Link in Lynch Syndrome Quashed by Aspirin
Obese individuals with Lynch syndrome have an increased risk for colorectal cancer that appears to be eliminated by regular aspirin. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 21, 2015 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

My diagnostic odyssey: The limits of genetic testing
I am on a “diagnostic odyssey.” That term was unfamiliar to me until I spoke with Joy Larsen Haidle, president of the National Society of Genetic Counselors, whose members help patients determine whether genetic testing for diagnostic purposes makes sense for them. I have an epileptic condition, but despite repeated visits with specialists over several years, I haven’t yet identified a root cause. I’ve only been able to treat and moderate symptoms with medication, and I’m pursuing genetic testing to see if we can discover how the condition started in the first place. As Larsen Haidle explained...
Source: Mass Device - August 20, 2015 Category: Medical Equipment Authors: Mark Hollmer Tags: Blog Diagnostics Source Type: news

Aspirin lowers risk of hereditary bowel cancer in obese people
ConclusionThis study followed up on a previous trial that found taking aspirin regularly reduced the risk of bowel cancer in people with the genetic condition Lynch syndrome (or HNPCC), which puts them at an increased risk of developing the disease. The study found being obese appears to further increase bowel cancer risk among people with this condition.It also found that BMI did not appear to have an effect on bowel cancer risk among those taking aspirin. While this might indicate that aspirin removes the effect of BMI, ideally a comparison of aspirin versus placebo in the different BMI groups is needed to further assess...
Source: NHS News Feed - August 18, 2015 Category: Consumer Health News Tags: Cancer Obesity Source Type: news

Aspirin lowers risk of cancer in overweight people: study
The study found that being overweight more than doubled the risk of bowel cancer in people with Lynch Syndrome, an inherited genetic disorder. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 18, 2015 Category: Pharmaceuticals Source Type: news

Multigene panel testing for hereditary breast/ovarian cancer risk assessment
(The JAMA Network Journals) Multigene testing of women negative for BRCA1 and BRCA2 found some of them harbored other harmful genetic mutations, most commonly moderate-risk breast and ovarian cancer genes and Lynch syndrome genes, which increase ovarian cancer risk, according to an article published online by JAMA Oncology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 13, 2015 Category: Cancer & Oncology Source Type: news

Tumor Tissue Screening Helps Spot Lynch SyndromeTumor Tissue Screening Helps Spot Lynch Syndrome
Checking for Lynch syndrome (LS) via germline mutations in mismatch repair (MMR) genes appears to be an effective and cost-saving strategy in patients with colorectal cancer (CRC), researchers say. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 10, 2015 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Medical News Today: Hormonal factors 'lower endometrial cancer risk' for women with Lynch syndrome
New research has identified some hormonal factors linked to reduced risk of endometrial cancer for women with Lynch syndrome - a genetic condition that increases cancer risk. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 8, 2015 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Association between genetic condition, hormonal factors, and risk of endometrial cancer
For women with Lynch syndrome, an association was found between the risk of endometrial cancer and the age of first menstrual cycle, having given birth, and hormonal contraceptive use, according to a study. Lynch syndrome is a genetic condition that increases the risk for various cancers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 7, 2015 Category: Science Source Type: news

Association between genetic condition, hormonal factors, and risk of endometrial cancer
(The JAMA Network Journals) For women with Lynch syndrome, an association was found between the risk of endometrial cancer and the age of first menstrual cycle, having given birth, and hormonal contraceptive use, according to a study in the July 7 issue of JAMA. Lynch syndrome is a genetic condition that increases the risk for various cancers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2015 Category: Cancer & Oncology Source Type: news

Chromoscopy and Adenoma Detection in Lynch SyndromeChromoscopy and Adenoma Detection in Lynch Syndrome
Is chromocolonoscopy more effective than standard colonoscopy at detecting adenomas in patients with Lynch syndrome? The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 25, 2015 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Chromoscopy May Boost Adenoma Yield in Lynch SyndromeChromoscopy May Boost Adenoma Yield in Lynch Syndrome
In patients with Lynch syndrome, colonoscopy with chromoscopy can detect adenomas that may be unseen with standard colonoscopy, according to French researchers. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - February 11, 2015 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Small-Bowel Neoplasia in Asymptomatic Lynch Syndrome: StudySmall-Bowel Neoplasia in Asymptomatic Lynch Syndrome: Study
The prevalence of small-bowel neoplasia in asymptomatic patients with Lynch syndrome is too low to warrant screening, researchers say. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 25, 2014 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Genetic Evaluation and Management of Lynch SyndromeGenetic Evaluation and Management of Lynch Syndrome
What do the latest guidelines say about genetic testing for and management of Lynch syndrome? The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 9, 2014 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Familial Colorectal Cancer, Beyond Lynch SyndromeFamilial Colorectal Cancer, Beyond Lynch Syndrome
How common is familial colorectal cancer, what do we have yet to learn about the disease, and how will an understanding of the genetic and epigenetic factors help with treatment down the road? Clinical Gastroenterology and Hepatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 1, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Immunochemistry of Skin Lesions Helps Spot Lynch SyndromeImmunochemistry of Skin Lesions Helps Spot Lynch Syndrome
Immunohistochemical screening of sebaceous neoplasms can identify germline mismatch repair (MMR) mutations and help diagnose Lynch syndrome, according to a new paper. Reuters Health Information (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - July 15, 2014 Category: Dermatology Tags: Hematology-Oncology News Source Type: news

Strategies for Cancer Prevention in Lynch SyndromeStrategies for Cancer Prevention in Lynch Syndrome
Since patients with Lynch syndrome could be at an increased risk for developing colorectal cancer, how can clinicians help prevent it in this subset of patients? Clinical Gastroenterology and Hepatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 16, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Does your family have the rogue bowel cancer gene?
LYNCH syndrome is deadly but new tests and treatment could help identify and beat it, says campaigner and bowel cancer survivor Lynn Faulds Wood (Source: Daily Express - Health)
Source: Daily Express - Health - June 3, 2014 Category: Consumer Health News Source Type: news

Lynch Syndrome From a Surgeon PerspectiveLynch Syndrome From a Surgeon Perspective
Preoperative identification of colorectal cancer patients with Lynch Syndrome may have a great clinical relevance in patient care strategies. BMC Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 19, 2014 Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news

NCCN: Test All Colorectal Cancers for Lynch SyndromeNCCN: Test All Colorectal Cancers for Lynch Syndrome
The guidance is in a new guideline from the National Comprehensive Cancer Network (NCCN). Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2014 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Quest Diagnostics Expands Hereditary Cancer Screening Offering with Lynch Syndrome Blood and Biopsy Testing for Colorectal Cancer
Company Supports March's Colorectal Cancer Awareness Month by Participating in the One Million Strong Screening Event in New York City on March 3 MADISON, N.J., Feb. 26, 2014 -- (Healthcare Sales & Marketing Network) -- Quest Diagnostics (DGX), the wor... Diagnostics, Oncology, Product LaunchQuest Diagnostics, Lynch syndrome, hereditary nonpolyposis colorectal cancer (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 26, 2014 Category: Pharmaceuticals Source Type: news

An international study allows a better prediction of the risk of hereditary cancer
(IDIBELL-Bellvitge Biomedical Research Institute) An international study has developed a refined method to identify people at risk for certain inherited cancer as a result of Lynch syndrome. The study, published in Nature Genetics has carried out clinical and basic researchers who are part of the INSIGHT (International Society for Gastroeintestinal Hereditary Tumours). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 15, 2014 Category: Cancer & Oncology Source Type: news

Prediction Models for Mismatch Repair Gene MutationsPrediction Models for Mismatch Repair Gene Mutations
This review catalogs the published criteria and prediction models available for determining which individuals and families are most likely to be carrying a MMR gene mutation for Lynch syndrome. Journal of Medical Genetics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 18, 2013 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Evidence mounts for endometrial cancer tumor testing to identify women with Lynch syndrome
(The Geisel School of Medicine at Dartmouth) Next to colorectal cancer, endometrial cancer is the most common form of cancer in women with Lynch syndrome. Mounting evidence suggests routine Lynch syndrome testing be done on every endometrial cancer specimen. Raising awareness of endometrial cancer's association with Lynch syndrome will identify more treatable cancers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 11, 2013 Category: Global & Universal Source Type: news

Refining the Role of PMS2 in Lynch SyndromeRefining the Role of PMS2 in Lynch Syndrome
This study analyzed the contribution of the PMS2 mismatch repair gene in Lynch syndrome by assessing the pathogenicity of variants of unknown significance. Journal of Medical Genetics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 12, 2013 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Lynch Syndrome: When to Screen and Whom to TellLynch Syndrome: When to Screen and Whom to Tell
Dr. Alok Khorana reports on a Cleveland Clinic study that identifies how best to implement screening guidelines for Lynch syndrome as well as the most effective way to inform patients of the results. Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 28, 2013 Category: Consumer Health News Tags: Hematology-Oncology Viewpoint Source Type: news

Project To Improve Molecular Diagnosis Of Lynch Syndrome
The Fundacion Mutua Madrilena, in its 10th Call for Aids to Research, has selected a project to improve the diagnosis of Lynch syndrome led by researcher Marta Pineda, from the Hereditary Cancer research group of the Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute of Oncology (ICO). The aid is provided with 33,000 euros and has a duration of two years. Hereditary predisposition to cancer Lynch syndrome is a hereditary predisposition to cancer caused by germline mutations in DNA repair genes... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 27, 2013 Category: Consumer Health News Tags: Colorectal Cancer Source Type: news