Aspirin lowers risk of hereditary bowel cancer in obese people
ConclusionThis study followed up on a previous trial that found taking aspirin regularly reduced the risk of bowel cancer in people with the genetic condition Lynch syndrome (or HNPCC), which puts them at an increased risk of developing the disease. The study found being obese appears to further increase bowel cancer risk among people with this condition.It also found that BMI did not appear to have an effect on bowel cancer risk among those taking aspirin. While this might indicate that aspirin removes the effect of BMI, ideally a comparison of aspirin versus placebo in the different BMI groups is needed to further assess...
Source: NHS News Feed - August 18, 2015 Category: Consumer Health News Tags: Cancer Obesity Source Type: news

Aspirin lowers risk of cancer in overweight people: study
The study found that being overweight more than doubled the risk of bowel cancer in people with Lynch Syndrome, an inherited genetic disorder. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 18, 2015 Category: Pharmaceuticals Source Type: news

Multigene panel testing for hereditary breast/ovarian cancer risk assessment
(The JAMA Network Journals) Multigene testing of women negative for BRCA1 and BRCA2 found some of them harbored other harmful genetic mutations, most commonly moderate-risk breast and ovarian cancer genes and Lynch syndrome genes, which increase ovarian cancer risk, according to an article published online by JAMA Oncology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 13, 2015 Category: Cancer & Oncology Source Type: news

Tumor Tissue Screening Helps Spot Lynch SyndromeTumor Tissue Screening Helps Spot Lynch Syndrome
Checking for Lynch syndrome (LS) via germline mutations in mismatch repair (MMR) genes appears to be an effective and cost-saving strategy in patients with colorectal cancer (CRC), researchers say. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 10, 2015 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Medical News Today: Hormonal factors 'lower endometrial cancer risk' for women with Lynch syndrome
New research has identified some hormonal factors linked to reduced risk of endometrial cancer for women with Lynch syndrome - a genetic condition that increases cancer risk. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 8, 2015 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Association between genetic condition, hormonal factors, and risk of endometrial cancer
For women with Lynch syndrome, an association was found between the risk of endometrial cancer and the age of first menstrual cycle, having given birth, and hormonal contraceptive use, according to a study. Lynch syndrome is a genetic condition that increases the risk for various cancers. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 7, 2015 Category: Science Source Type: news

Association between genetic condition, hormonal factors, and risk of endometrial cancer
(The JAMA Network Journals) For women with Lynch syndrome, an association was found between the risk of endometrial cancer and the age of first menstrual cycle, having given birth, and hormonal contraceptive use, according to a study in the July 7 issue of JAMA. Lynch syndrome is a genetic condition that increases the risk for various cancers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 7, 2015 Category: Cancer & Oncology Source Type: news

Chromoscopy and Adenoma Detection in Lynch SyndromeChromoscopy and Adenoma Detection in Lynch Syndrome
Is chromocolonoscopy more effective than standard colonoscopy at detecting adenomas in patients with Lynch syndrome? The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 25, 2015 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Chromoscopy May Boost Adenoma Yield in Lynch SyndromeChromoscopy May Boost Adenoma Yield in Lynch Syndrome
In patients with Lynch syndrome, colonoscopy with chromoscopy can detect adenomas that may be unseen with standard colonoscopy, according to French researchers. Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - February 11, 2015 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Aspirin Tied to Lasting Reduction in CRC Risk in Lynch Syndrome
Reduced risk for colorectal cancer seen in intention - to - treat and per - protocol analyses (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - November 11, 2014 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Internal Medicine, Oncology, Pharmacy, Journal, Source Type: news

Small-Bowel Neoplasia in Asymptomatic Lynch Syndrome: StudySmall-Bowel Neoplasia in Asymptomatic Lynch Syndrome: Study
The prevalence of small-bowel neoplasia in asymptomatic patients with Lynch syndrome is too low to warrant screening, researchers say. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 25, 2014 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Genetic Evaluation and Management of Lynch SyndromeGenetic Evaluation and Management of Lynch Syndrome
What do the latest guidelines say about genetic testing for and management of Lynch syndrome? The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 9, 2014 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Familial Colorectal Cancer, Beyond Lynch SyndromeFamilial Colorectal Cancer, Beyond Lynch Syndrome
How common is familial colorectal cancer, what do we have yet to learn about the disease, and how will an understanding of the genetic and epigenetic factors help with treatment down the road? Clinical Gastroenterology and Hepatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 1, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Immunochemistry of Skin Lesions Helps Spot Lynch SyndromeImmunochemistry of Skin Lesions Helps Spot Lynch Syndrome
Immunohistochemical screening of sebaceous neoplasms can identify germline mismatch repair (MMR) mutations and help diagnose Lynch syndrome, according to a new paper. Reuters Health Information (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - July 15, 2014 Category: Dermatology Tags: Hematology-Oncology News Source Type: news

Strategies for Cancer Prevention in Lynch SyndromeStrategies for Cancer Prevention in Lynch Syndrome
Since patients with Lynch syndrome could be at an increased risk for developing colorectal cancer, how can clinicians help prevent it in this subset of patients? Clinical Gastroenterology and Hepatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 16, 2014 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news