A Rare Complication of a Common Disease
BY ANUMEHA SINGH, MD, &ANDREJ KIELTYKA, PASymptomatic bradycardia is usually reserved for the over-the-hill crowd, but it is not entirely unheard of in the young and healthy. A 21-year-old African American man was sent to the emergency department by his primary care provider. The patient had no previous medical issues, normal vital signs, and was fine until about a week prior. He had quickly worsening shortness of breath while climbing the stairs to get to his dorm bedroom. The young man denied having been out in the woods or noting tick bites. He had no family history of cardiomyopathy or early cardiac events.The patient had negative toxicology and social history screens. When pressed further, he recalled malaise, stiff neck, low-grade temperature, and muscle aches for about two weeks prior to exertional dyspnea onset. As it turned out, he went to a bonfire party for his graduating college class about three weeks before presentation. He thought the malaise was just a cold, and only the exertional component brought him and his mom to his doctor for evaluation.A heart block with a heart rate of 36 bpm was noted on an ECG in the office, which was then compared with the normal sinus rhythm from previous ECGs. The patient was directed to the emergency department for further testing. The patient appeared well, had no advantageous heart sounds, and had an essentially normal exam with no skin rash besides a heart rate of 44 bpm and a third-degree heart block on ECG.The cli...
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Condition: Tick Borne Encephalitis Interventions: Drug: Doxycycline; Drug: Symptomatic therapy; Other: Questionnaire Sponsors: University Medical Centre Ljubljana; University of Ljubljana School of Medicine, Slovenia Recruiting
A small town in Oklahoma is warning communities about the Trump administration's environmental policies
Authors: Chen Q, Peng D Abstract Plant-parasitic nematode infection is a global problem for agriculture and forestry. There is clearly a need for novel nematicides, because of the pitifully small repertoire of nematicides available and the effectiveness of losing or environmental prohibition of these nematicides. Chitin is the essential component of nematode eggshell and pharynx. The disturbance of chitin synthesis or hydrolysis led to nematode embryonic lethal, laying defective eggs or moulting failure. Thus, the key components in the chitin metabolic process are promising targets for anti-nematode agent's develop...
Authors: Steinfeld L, Vafaei A, Rösner J, Merzendorfer H Abstract Chitin is an important structural polysaccharide, which supports and organizes extracellular matrices in a variety of taxonomic groups including bacteria, fungi, protists, and animals. Additionally, chitin has been recognized as a molecule that is required for Rhizobia-legume symbiosis and involved in arbuscular mycorrhizal signaling in the symbiotic interaction between terrestrial plants and fungi. Moreover, it serves as a unique molecular pattern in the plant defense system against pathogenic fungi and parasites, and in the innate and adaptive...
Authors: Yang Q, Fukamizo T Abstract Chitin is a linear biopolymer composed of β-1,4-linked N-acetylglucosamine (GlcNAc), and an essential component in exoskeleton of insects and crustaceans, the egg shells of parasitic nematodes, and the fungal cell wall. Since the chitin-containing organisms often threaten human health, food safety, and agricultural production, it has been highly desirable to control the hazardous chitin-containing organisms. This book will provide researchers and students with information on the recent research progress about the biology of chitin-containing organisms and their cross-talk w...
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