Old meningitis B vaccine 'may also protect against gonorrhoea'

Conclusion This large study found an association between having the MeNZB vaccine and a reduced likelihood of being diagnosed with gonorrhoea. But it's difficult to form any firm conclusions because of the nature of the case and control groups. For example, given that both groups were sexually active, we don't know why the majority of people with gonorrhoea didn't also have a chlamydia infection, and how this may have affected the results. It could just be down to pure chance and have nothing to do with the vaccine. So before we celebrate the alleged "cure of gonorrhoea", there are many things to consider: The vaccine in question is no longer in use as a vaccine against meningococcal B. The Men4C jab is now used in the UK. Though it does have many similar components, we don't know if these are useful in protecting against gonorrhoea. Research now needs to focus on whether the association still exists with the new jab. Although the authors adjusted for some variables, other factors might be at play that may have affected the results, such as people's education, diet, and immune system strength. No new vaccine has actually been developed. The indication that something in the MeNZB vaccine might increase protection against gonorrhoea requires further research to pinpoint how it does so. The research was only conducted on people who were diagnosed at a sexual health clinic, and didn't include data from GP surgeries. Many cases in the community could have been...
Source: NHS News Feed - Category: Consumer Health News Tags: Medication Source Type: news

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Conclusion: The presence of headache, mood disorders, psychosis, depression, and other neuropsychological manifestations in a patient with JSLE should prompt investigations into diagnosis of the primary nervous system involvement in order to reduce mortality and morbidity. PMID: 30002929 [PubMed]
Source: Neurology Research International - Category: Neurology Tags: Neurol Res Int Source Type: research
VITAMIN D deficiency could cause bone deformities and pain, meaning it is important to get enough from daily activities and in the diet. The essential vitamin can easily be obtained by either standing in sunlight or eating certain foods. Try eating this to help avoid a vitamin D deficiency.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
ConclusionsThe pernicious effect of high vancomycin MIC disappears in the absence of a predominant use of this antibiotic. However, a high daptomycin MIC in MRSA bacteraemia is associated with higher mortality in patients with bacteraemia, irrespective of antimicrobial treatment choice.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
GIDEON what’s new summary: July 12 to July 15, 2018 Infectious Diseases – Outbreaks (12 updates) 12 DiseasesMap Infectious Diseases – Diseases (122 updates) 42 Diseases80 Country notesMap Infectious Diseases – Drugs (22 updates) 1 New Drugs Added20 Drugs1 New Drug Synonyms Added Infectious Diseases – Vaccines (4 updates) 4 Vaccines Microbiology – Bacteria (8 updates) 3 New Bacteria Added3 New Bacteria Synonyms Added2 Microbes – Update The post Update: July 15, 2018 appeared first on GIDEON - Global Infectious Diseases and Epidemiology Online Network.
Source: GIDEON blog - Category: Databases & Libraries Authors: Tags: What's New Source Type: blogs
Authors: Kotfis K, Zegan-Barańska M, Strzelbicka M, Safranow K, Żukowski M, Ely EW, POL-CPOT Study Group Abstract Introduction: Pain in the critically ill affects nearly 50% of patients. In patients unable to self-report pain, behavioural scales are used. The aim of this study was to validate the Polish version of the Critical Care Pain Observation Tool (CPOT). Material and methods: The prospective observational cohort study included patients observed during non-nociceptive and nociceptive procedures, at rest, during the intervention, and 15 min after each intervention. Assessments included self-report by pat...
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
Conclusions: Oral ibuprofen may be superior to MNNM for pain reduction and upper limb function increase of subjects with CP. Nevertheless, both treatments were effective. Median nerve neural mobilization may be considered an effective non-pharmaceutical treatment option in subjects with CP. Regarding OI adverse effects, our findings challenge the role of pharmacologic versus manual therapy as possible treatments that may improve pain intensity and upper limb functionality in subjects with CP. PMID: 30002707 [PubMed]
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
Conclusion: Clinical findings become indistinct by age, and differential diagnosis of abdominal pain gets more difficult in geriatric patients. Therefore, physicians should consider age related physiological changes in order to distinguish geriatric patients admitted to emergency service with abdominal pain from pathological cases requiring immediate surgical operation. PMID: 30002677 [PubMed]
Source: Current Gerontology and Geriatrics Research - Category: Geriatrics Tags: Curr Gerontol Geriatr Res Source Type: research
This study aimed to evaluate the performance of a new Franseen tip fine needle biopsy (FNB) device for EUSguided sampling of solid lesions and compare it with the historical FNA technique. Methods: Acquire® 22 G FNB needle (Boston Scientific Co., Natick, MA, USA) was used for solid tumor sampling (Study group). Tissue was collected for rapid on-site evaluation, and touch and crush preparations were made. Historical EUS-FNA samples obtained using Expect® 22 G FNA needle (Boston Scientific Co.) were used as controls (Control group). All specimens were independently evaluated by two cytopathologists blinded to the...
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
This study sought to compare the effects of proximal femoral nail anti-rotation (PFNA) and dynamic hip screw (DHS) helical blade treatments in patients with osteoporotic femoral intertrochanteric fractures. PATIENTS AND METHODS: Eighty elderly osteoporosis patients with femoral intertrochanteric fracture complications admitted to the hospital between January 2013 and December 2014 were selected and divided into control (n=40) and observation (n=40) groups. The control group received DHS internal fixation while the observation group received PFNA treatment. Patients were followed up for 18 months, during which pre- and ...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Authors: Zhang R, Zhang SJ, Wang XJ Abstract OBJECTIVE: To explore the effects of postoperative functional exercise on patients who underwent percutaneous transforaminal endoscopic discectomy for lumbar disc herniation. PATIENTS AND METHODS: From January to May 2011, patients who had a lumbar disc herniation and then underwent percutaneous transforaminal endoscopic discectomy were divided randomly into two groups: the intervention group (n=46) and the control group (n=46). The intervention group conducted early functional exercises of passive and autonomic activities after their operations, while the control gr...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
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