Worse Prognosis in Lung Cancer Patients can be Predicted by 99TcmN-NOET Dual-phase SPECT of More Accumulation

Conclusion: The more accumulation of 99TcmN-NOET dual-phase SPECT was associated with worse prognosis in patients with lung cancer. In long-term follow-up, the semi quantitative index of 99TcmN-NOET dual-phase SPECT could be proved highly predictive of poor prognosis in patients with lung cancer, and hence deserves further investigation. [Key words] lung cancer, prognostic, 99TcmN-NOET, SPECT b Fig1:65-year-old, male, squamous cell carcinoma of upper right lung. There was a larger, irregular and increased distribution area of upper right lung of 99TcmN-NOET SPECT(a)and of CT(b,c).The result of follow up was death on Sep 26, 2015. Fig.2 Kaplan-Meier curves of overall survival according to medium Early T/NT (upper) and Delay T/NT (lower), showing lower Early T/NT or Delay T/NT associated with better overall survival, and higher Early T/NT or Delay T/NT associated with worsening overall survival.Tab. 1 Patient characteristics and overall survival based on stage, gender, age, tumor histology, treatment, and SPECT 99mTcN-NOET measurements of patients with lung cancer.VariablesNPercentage (%)All51100.0GenderMale3670.6Female1529.4Age year (mean±SD)60.3±10.6<60(median)2243.1>=602956.9BMI (mean±SD)22.5±3.1<22.48(median)2549>=22.482651Smoking historyPrior3.05.9Never22.043.1Current26.051.0TNM stageIA/IB1/1121.6IIA/IIB1/1631.4IIIA/IIIB1/1835.3IV611.8HistologyAdeno1325.5Squamous3058.2Other815.7TreatmentSurg2651.0Surg + RT/Chem/RT+Chem917.7Chem/Chem+...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Lung Cancer I Source Type: research