Blood Clots, Deep Vein Thrombosis and Pulmonary Embolism

What is Deep Vein Thrombosis (DVT)? DVT is the formation of a blood clot (thrombus) within a deep vein. The deep veins pass through deep tissues and muscles. Muscle contractions (walking, running, activity, etc.) squeeze blood through the deep veins to the heart. The deep veins have valves which prevent blood from flowing back to the ankles and feet. The majority of blood clots are small and are usually broken down or dissolved. Large clots may form and can block the vein causing the patient to complain of pain and swelling. Homan's sign is not very specific. High index of suspicion is necessary for diagnosis. Virchow's Triad contributes to the development of deep venous thrombosis. 1. Endothelial Injury. 2. Venous Stasis. 3. Hypercoagulability. One triad may contribute more than others. RISK FACTORS: •History of DVT (most important). •Tumor (malignancy). -- Up to 20% •Oral contraceptive therapy. •Aging. •Obesity. •Smoking. •The Virchow's Triad: -- Venous Stasis - Immobilization (patient stays in bed). - Physical therapy is not available. - Being on an airplane or in a car for a long period of time without movement and not taking aspirin. -- Intimal injury - Due to trauma, fracture dislocation or results from surgery. - Surgery itself is a risk factor because of the use of general anesthesia and stress of the surgery. -- Hypercoagulable State - Could be inherited/genetics (Factor V Leiden, Protein S deficiency, Protein C...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Publication date: January 2020Source: Biometric Technology Today, Volume 2020, Issue 1Author(s): US NIST (the National Institute of Standards and Technology) has released three new biometric databases – featuring fingerprints, facial photographs and iris scans – designed to help researchers reduce the error rates of biometric systems.
Source: Biometric Technology Today - Category: Information Technology Source Type: research
Publication date: January 2020Source: Biometric Technology Today, Volume 2020, Issue 1Author(s): Jason TooleyThe use of biometrics by police forces has rarely been out of the headlines over the past year. As with many emerging technologies, it has hit significant hurdles. Recently in an unprecedented move, the UK's Information Commissioner's Office (ICO) – the government body responsible for GDPR and data privacy enforcement – launched an independent investigation into the use of facial recognition at London's King's Cross train station, after it was revealed that the general public were having their faces scan...
Source: Biometric Technology Today - Category: Information Technology Source Type: research
Conclusion Anlotinib effectively controlled the growth of NSCLC and improved TAO related symptoms. Anlotinib maybe normalize disordered growth of blood vessels through the VEGF signaling pathway, rather than simply inhibiting angiogenesis. 
 DOI: 10.3779/j.issn.1009-3419.2020.01.10
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
In this research, the hydrothermal method was used for synthesising cellulose acetate (CA) templated nanorods like CuS fibres using vegetable extract (Brassica oleracea var. italica). These extracts act as a reducing agent in the presence of CA. Surprisingly, when the same reaction was carried out in the absence of CA and broccoli extract, structural morphology disappeared and was found as agglomerated. In the presence of cellulose templated extract mediated CuS has revealed as nanorods like fibres and was confirmed by field emission scanning electron microscope analysis. Their crystallinity property of CuS nanoparticles (...
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
To sustained release of an anticancer drug, oxaliplatin (OX), a non-toxic and biocompatible nanocarrier based on bovine serum albumin (BSA) were synthesised by desolvation method and characterised using Fourier-transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), atomic force microscopy (AFM) and dynamic light scattering. The results showed that the BSA nanoparticles (BSANPs) with a mean magnitude of 187.9 ± 1.2 nm have spherical morphology with a smooth surface and a uniform distribution. Furthermore, OX was loaded onto the BSANPs and the loading was confirmed...
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
Publication date: Available online 15 January 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Anna Xu, Bart Larsen, Erica B. Baller, J. Cobb Scott, Vaishnavi Sharma, Azeez Adebimpe, Allan I. Basbaum, Robert H. Dworkin, Robert R. Edwards, Clifford J. Woolf, Simon B. Eickhoff, Claudia R. Eickhoff, Theodore D. SatterthwaiteAbstractCharacterizing a reliable, pain-related neural signature is critical for translational applications. Many prior fMRI studies have examined acute nociceptive pain-related brain activation in healthy participants. However, synthesizing these data to identify convergent patterns of activa...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Publication date: Available online 15 January 2020Source: The Annals of Thoracic SurgeryAuthor(s): Yuting Chiang
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Authors: Baumann S, Bojara W, Post H, Rudolph T, Schäufele T, Ong P, Lehmann R, von Zur Mühlen C Abstract The regulation of coronary flow is mainly located in the resistance vessels of the microcirculation, so that the functional relevance of a coronary stenosis arises from the interaction between the epicardial stenosis and the downstream microcirculation. These complex interactions are precisely detectable by physiological measurements, such as the instantaneous wave-free ratio (iwFR) or the fractional flow reserve (FFR). In contrast, the purely visual assessment of the coronary anatomy could lead ...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Publication date: Available online 15 January 2020Source: Journal of Molecular StructureAuthor(s): J. Mobika, M. Rajkumar, V. Nithya Priya, S.P. Linto SibiAbstractNano-biocomposites that mimics bone’s extracellular matrix with hydroxyapatite as an inorganic and silk fibroin as organic phase for three different ratios via a simple in-situ co-precipitation method have been synthesized. The silk fibroin, a biodegradable polymer from cocoons of Bombyx mori silkworm were extracted by employing a chemical-free High-Temperature High-Pressure method as a degumming route. Then followed by the regeneration process which was do...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 15 January 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Susmita Biswas, Udita Chatterjee, Sriparnika Sarkar, Finaz Khan, Debbethi Bera, Madhumita Mukhopadhyay, Soumyabrata Goswami, Sandip Chakrabarti, Susmita DasAbstractLow Molecular Weight (LMWG) gelators are small molecules that form supramolecular self-assembly involving physical forces and are highly biocompatible. However, fragility of these physical gels restricts their applicability where gels of higher mechanical strength are required. Herein, we have developed two different types of 2-D carbon nanomaterials viz. g...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
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